Krishnankutty C. Sivakumar
YOU?
Author Swipe
View article: Supplementary Movie 2 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Movie 2 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
AVI - 1278KB, Supplemental Movie SM2: Molecular simulation of DAT1 bound to tubulin at lower pH.
View article: Supplementary Movie 4 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Movie 4 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
AVI - 1146KB, Supplemental Movie SM3: Molecular simulation of colchicine bound to tubulin at higher pH.
View article: Supplementary Materials and Methods and Supplementary Figure Legends from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Materials and Methods and Supplementary Figure Legends from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
PDF - 74KB, Supplementary Materials and Methods and Figure Legends.
View article: Supplementary Movie 2 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Movie 2 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
AVI - 1278KB, Supplemental Movie SM2: Molecular simulation of DAT1 bound to tubulin at lower pH.
View article: Supplementary Figure 2 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Figure 2 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
PDF - 3904KB, Supplemental Fig S2: Reversible action of DAT1 on mitotic block and cell morphology in HeLa cells.
View article: Supplementary Figure 4 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Figure 4 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
PDF - 3082KB, Supplemental Fig S4: Number of Hydrogen bonds as a function of time.
View article: Supplementary Movie 1 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Movie 1 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
AVI - 1269KB, Supplemental Movie SM1: Molecular simulation of DAT1 bound to tubulin at higher pH.
View article: Supplementary Movie 4 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Movie 4 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
AVI - 1221KB, Supplemental Movie SM4: Molecular simulation of colchicine bound to tubulin at lower pH.
View article: Supplementary Movie 4 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Movie 4 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
AVI - 1221KB, Supplemental Movie SM4: Molecular simulation of colchicine bound to tubulin at lower pH.
View article: Supplementary Materials and Methods and Supplementary Figure Legends from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Materials and Methods and Supplementary Figure Legends from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
PDF - 74KB, Supplementary Materials and Methods and Figure Legends.
View article: Supplementary Figure 1 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Figure 1 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
PDF - 4536KB, Supplemental Fig S1: Reversible action of DAT1 on mitotic block and cell morphology in HCT 116 cells.
View article: Supplementary Movie 1 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Movie 1 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
AVI - 1269KB, Supplemental Movie SM1: Molecular simulation of DAT1 bound to tubulin at higher pH.
View article: Supplementary Movie 4 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Movie 4 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
AVI - 1146KB, Supplemental Movie SM3: Molecular simulation of colchicine bound to tubulin at higher pH.
View article: Supplementary Figure 1 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Figure 1 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
PDF - 4536KB, Supplemental Fig S1: Reversible action of DAT1 on mitotic block and cell morphology in HCT 116 cells.
View article: Supplementary Figure 4 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Figure 4 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
PDF - 3082KB, Supplemental Fig S4: Number of Hydrogen bonds as a function of time.
View article: Supplementary Figure 3 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Figure 3 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
PDF - 479KB, Supplemental Fig S3: Effect of pH on colchicine binding to tubulin.
View article: Supplementary Figure 3 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Figure 3 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
PDF - 479KB, Supplemental Fig S3: Effect of pH on colchicine binding to tubulin.
View article: Supplementary Figure 2 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Supplementary Figure 2 from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
PDF - 3904KB, Supplemental Fig S2: Reversible action of DAT1 on mitotic block and cell morphology in HeLa cells.
View article: Data from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Data from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
Diaminothiazoles are novel cytotoxic compounds that have shown efficacy toward different cancer cell lines. They show potent antimitotic and antiangiogenic activity upon binding to the colchicine-binding site of tubulin. However, the mecha…
View article: Data from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics
Data from Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics Open
Diaminothiazoles are novel cytotoxic compounds that have shown efficacy toward different cancer cell lines. They show potent antimitotic and antiangiogenic activity upon binding to the colchicine-binding site of tubulin. However, the mecha…
View article: Novel small synthetic HIV-1 V3 crown variants: CCR5 targeting ligands
Novel small synthetic HIV-1 V3 crown variants: CCR5 targeting ligands Open
The CC chemokine receptor 5 (CCR5) antagonism represents a promising pharmacological strategy for therapeutic intervention as it plays a significant role in reducing the severity and progression of a wide range of pathological conditions. …
View article: Pax6 modulates intra-retinal axon guidance and fasciculation of retinal ganglion cells during retinogenesis
Pax6 modulates intra-retinal axon guidance and fasciculation of retinal ganglion cells during retinogenesis Open
Intra-retinal axon guidance involves a coordinated expression of transcription factors, axon guidance genes, and secretory molecules within the retina. Pax6, the master regulator gene, has a spatio-temporal expression typically restricted …
View article: Binding of alpha‐fodrin to gamma‐tubulin accounts for its role in the inhibition of microtubule nucleation
Binding of alpha‐fodrin to gamma‐tubulin accounts for its role in the inhibition of microtubule nucleation Open
Non‐erythroid spectrin or fodrin is present as part of the γ‐tubulin ring complex (γ‐Tu RC ) in brain tissue and brain derived cells. Here, we show that fodrin, which is otherwise known for providing structural support to the cell membrane…
View article: The multiple stress responsive transcriptional regulator Rv3334 of <i>Mycobacterium tuberculosis</i> is an autorepressor and a positive regulator of <i>kstR</i>
The multiple stress responsive transcriptional regulator Rv3334 of <i>Mycobacterium tuberculosis</i> is an autorepressor and a positive regulator of <i>kstR</i> Open
Rv3334 protein of Mycobacterium tuberculosis belongs to the MerR family of transcriptional regulators and is upregulated during hypoxia and other stress conditions. Employing GFP reporter constructs, mobility shift assays and Ch IP assays,…