Sivan G. Marcus
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View article: Close Enough? Feasibility, Success, and Sustainability of Critical Care Echocardiography Curricula
Close Enough? Feasibility, Success, and Sustainability of Critical Care Echocardiography Curricula Open
View article: Goal-Directed Therapy in Liver Surgery
Goal-Directed Therapy in Liver Surgery Open
Purpose of Review This review summarizes the updated literature on goal-directed therapy during liver surgery. It provides guidance for clinicians regarding physiologic concepts and clinical evidence related to fluid and hemodynamic manage…
View article: Angiotensin II in liver transplantation (AngLT-1): protocol of a randomised, double-blind, placebo-controlled trial
Angiotensin II in liver transplantation (AngLT-1): protocol of a randomised, double-blind, placebo-controlled trial Open
Introduction Catecholamine vasopressors such as norepinephrine are the standard drugs used to maintain mean arterial pressure during liver transplantation. At high doses, catecholamines may impair organ perfusion. Angiotensin II is a pepti…
View article: The H-Y Antigen in Embryonic Stem Cells Causes Rejection in Syngeneic Female Recipients
The H-Y Antigen in Embryonic Stem Cells Causes Rejection in Syngeneic Female Recipients Open
Pluripotent stem cells are promising candidates for cell-based regenerative therapies. To avoid rejection of transplanted cells, several approaches are being pursued to reduce immunogenicity of the cells or modulate the recipient's immune …
View article: Hybrid Open Minimally Invasive Transcatheter Mitral Valve Replacement
Hybrid Open Minimally Invasive Transcatheter Mitral Valve Replacement Open
View article: TGF-β1/CD105 signaling controls vascular network formation within growth factor sequestering hyaluronic acid hydrogels
TGF-β1/CD105 signaling controls vascular network formation within growth factor sequestering hyaluronic acid hydrogels Open
Cell-based strategies for the treatment of ischemic diseases are at the forefront of tissue engineering and regenerative medicine. Cell therapies purportedly can play a key role in the neovascularization of ischemic tissue; however, low su…
View article: μOrgano: A Lego®-Like Plug & Play System for Modular Multi-Organ-Chips
μOrgano: A Lego®-Like Plug & Play System for Modular Multi-Organ-Chips Open
Human organ-on-a-chip systems for drug screening have evolved as feasible alternatives to animal models, which are unreliable, expensive, and at times erroneous. While chips featuring single organs can be of great use for both pharmaceutic…
View article: Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications
Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications Open
Drug discovery and development are hampered by high failure rates attributed to the reliance on non-human animal models employed during safety and efficacy testing. A fundamental problem in this inefficient process is that non-human animal…