Songqing He
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View article: Tree trunk disease mapping using hyperspectral LiDAR
Tree trunk disease mapping using hyperspectral LiDAR Open
View article: Retraction Note: m6A demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling
Retraction Note: m6A demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling Open
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12943-019-1128-6.
View article: Self-supervised learning model integrates plain and contrast-enhanced CT for preoperatively identifying gangrenous cholecystitis: a multicenter retrospective cohort study
Self-supervised learning model integrates plain and contrast-enhanced CT for preoperatively identifying gangrenous cholecystitis: a multicenter retrospective cohort study Open
Background: Gangrenous cholecystitis (GC) is a severe complication of acute cholecystitis that requires prompt surgical intervention. However, its preoperative diagnosis remains challenging due to the limitations of traditional imaging tec…
View article: Synchronous hepatectomy and splenectomy for patients with BCLC stage 0/A hepatocellular carcinoma and clinically significant portal hypertension: A multicenter retrospective cohort study
Synchronous hepatectomy and splenectomy for patients with BCLC stage 0/A hepatocellular carcinoma and clinically significant portal hypertension: A multicenter retrospective cohort study Open
View article: AP5Z1 affects hepatocellular carcinoma growth and autophagy by regulating PTEN ubiquitination and modulating the PI3K/Akt/mTOR pathway
AP5Z1 affects hepatocellular carcinoma growth and autophagy by regulating PTEN ubiquitination and modulating the PI3K/Akt/mTOR pathway Open
View article: The Hands teaching method helps recognize the anatomy of the right posterior branch of the portal vein
The Hands teaching method helps recognize the anatomy of the right posterior branch of the portal vein Open
View article: Retraction Note: Lnc-PDZD7 contributes to stemness properties and chemosensitivity in hepatocellular carcinoma through EZH2- mediated ATOH8 transcriptional repression
Retraction Note: Lnc-PDZD7 contributes to stemness properties and chemosensitivity in hepatocellular carcinoma through EZH2- mediated ATOH8 transcriptional repression Open
View article: The LncRNA lnc-POTEM-4:14 promotes HCC progression by interacting with FOXK1
The LncRNA lnc-POTEM-4:14 promotes HCC progression by interacting with FOXK1 Open
View article: Liver resection in stage 0-A HCC in segments 7/8: a propensity-matched analysis comparing open, laparoscopic, and robotic approach
Liver resection in stage 0-A HCC in segments 7/8: a propensity-matched analysis comparing open, laparoscopic, and robotic approach Open
View article: nnHCCNeXt: A Lightweight Algorithm for Hepatocellular Carcinoma Segmentation in 3D Venous Phase CT Imaging
nnHCCNeXt: A Lightweight Algorithm for Hepatocellular Carcinoma Segmentation in 3D Venous Phase CT Imaging Open
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related mortality globally, and its diagnosis and treatment rely heavily on precise CT imaging, with tumor segmentation being critical for treatment planning. Current segm…
View article: Association between high-density lipoprotein cholesterol and the risk of incident diabetes in the prediabetic and the normoglycemic Japanese men: A population-base longitudinal cohort study
Association between high-density lipoprotein cholesterol and the risk of incident diabetes in the prediabetic and the normoglycemic Japanese men: A population-base longitudinal cohort study Open
Background While many studies indicate a negative correlation between high-density lipoprotein cholesterol (HDL-C) and the occurrence of diabetes, there are still some inconsistent findings. The contentious relationship between the two may…
View article: FABP4 deficiency ameliorates alcoholic steatohepatitis in mice via inhibition of p53 signaling pathway
FABP4 deficiency ameliorates alcoholic steatohepatitis in mice via inhibition of p53 signaling pathway Open
View article: Identification of diagnostic markers and molecular clusters of cuproptosis-related genes in alcohol-related liver disease based on machine learning and experimental validation
Identification of diagnostic markers and molecular clusters of cuproptosis-related genes in alcohol-related liver disease based on machine learning and experimental validation Open
View article: Identification and validation of cuproptosis-related genes in acetaminophen-induced liver injury using bioinformatics analysis and machine learning
Identification and validation of cuproptosis-related genes in acetaminophen-induced liver injury using bioinformatics analysis and machine learning Open
Background Acetaminophen (APAP) is commonly used as an antipyretic analgesic. However, acetaminophen overdose may contribute to liver injury and even liver failure. Acetaminophen-induced liver injury (AILI) is closely related to mitochondr…
View article: FABP4 deficiency ameliorates alcoholic steatohepatitis in mice via inhibition of p53 signaling pathway
FABP4 deficiency ameliorates alcoholic steatohepatitis in mice via inhibition of p53 signaling pathway Open
Fatty acid-binding protein 4 (FABP4) plays an essential role in metabolism and inflammatory. However, the role of FABP4 in alcoholic steatohepatitis (ASH) remains unclear. This study aimed to investigate the function of FABP4 and the under…
View article: Identification and validation of potential diagnostic signature and immune cell infiltration for HIRI based on cuproptosis-related genes through bioinformatics analysis and machine learning
Identification and validation of potential diagnostic signature and immune cell infiltration for HIRI based on cuproptosis-related genes through bioinformatics analysis and machine learning Open
Background and aims Cuproptosis has emerged as a significant contributor in the progression of various diseases. This study aimed to assess the potential impact of cuproptosis-related genes (CRGs) on the development of hepatic ischemia and…
View article: Burden of liver cancer due to hepatitis C from 1990 to 2019 at the global, regional, and national levels
Burden of liver cancer due to hepatitis C from 1990 to 2019 at the global, regional, and national levels Open
Background Liver cancer due to hepatitis C (LCDHC) is one of the leading causes of cancer-related deaths worldwide, and the burden of LCDHC is increasing. We aimed to report the burden of LCDHC at the global, regional, and national levels …
View article: Up-regulation of scleral C5b-9 and its regulation of the NLRP3 inflammasome in a form-deprivation myopia mouse model
Up-regulation of scleral C5b-9 and its regulation of the NLRP3 inflammasome in a form-deprivation myopia mouse model Open
Complement cascades are activated in FD myopia model. Upregulation of C5b-9 might participate in scleral remodeling during myopia progression via regulation of NLRP3 inflammasome activation.
View article: Global burden of cirrhosis and other chronic liver diseases due to nonalcoholic fatty liver disease, 1990-2019
Global burden of cirrhosis and other chronic liver diseases due to nonalcoholic fatty liver disease, 1990-2019 Open
BACKGROUND Nonalcoholic fatty liver disease (NAFLD) has become the leading cause of cirrhosis and other chronic liver diseases (COCLDs). AIM To conduct a comprehensive and comparable updated analysis of the global, regional, and national b…
View article: FBXL19 promotes malignant behaviours by activating MAPK signalling and negatively correlates with prognosis in hepatocellular carcinoma
FBXL19 promotes malignant behaviours by activating MAPK signalling and negatively correlates with prognosis in hepatocellular carcinoma Open
View article: Cushing's syndrome presenting as non‐atherosclerotic myocardial infarction and heart failure
Cushing's syndrome presenting as non‐atherosclerotic myocardial infarction and heart failure Open
Cushing's syndrome is a rare cause of myocardial infarction and heart failure. Herein, we report a female patient who presented acute myocardial infarction and heart failure with reduced ejection fraction. The patient was found to have hyp…
View article: The Diagnostic Performance of Contrast-Enhanced Computed Tomography and Contrast-Enhanced Ultrasound in Hepatocellular Carcinoma
The Diagnostic Performance of Contrast-Enhanced Computed Tomography and Contrast-Enhanced Ultrasound in Hepatocellular Carcinoma Open
Objective: To investigate the sensitivity, specificity and diagnostic accuracy of contrast-enhanced computed tomography (CECT) and contrast-enhanced ultrasound (CEUS) for hepatocellular carcinoma (HCC). Methods: The clinical data of patien…
View article: Identification and validation of potential diagnostic signature and immune cell infiltration for NAFLD based on cuproptosis-related genes by bioinformatics analysis and machine learning
Identification and validation of potential diagnostic signature and immune cell infiltration for NAFLD based on cuproptosis-related genes by bioinformatics analysis and machine learning Open
Background and aims Cuproptosis has been identified as a key player in the development of several diseases. In this study, we investigate the potential role of cuproptosis-related genes in the pathogenesis of nonalcoholic fatty liver disea…
View article: Transcriptome sequencing and metabolome analysis reveal the metabolic reprogramming of partial hepatectomy and extended hepatectomy
Transcriptome sequencing and metabolome analysis reveal the metabolic reprogramming of partial hepatectomy and extended hepatectomy Open
Surgical resection remains a critical treatment option for many patients with primary and secondary hepatic neoplasms. Extended hepatectomy (eHx) may be required for some patients with large tumors, which may cause liver failure and death.…
View article: Identification of a novel cuproptosis-related pattern and its tumor microenvironment infiltration characteristics in pancreatic cancer
Identification of a novel cuproptosis-related pattern and its tumor microenvironment infiltration characteristics in pancreatic cancer Open
Purpose Cuproptosis is a novel mechanism of copper-dependent cell death mechanism that can regulate the progression, immune response, and prognosis of tumors. However, the potential roles of cuproptosis-related genes (CRGs) in the clinical…
View article: Blockade of C5aR1 alleviates liver inflammation and fibrosis in a mouse model of NASH by regulating TLR4 signaling and macrophage polarization
Blockade of C5aR1 alleviates liver inflammation and fibrosis in a mouse model of NASH by regulating TLR4 signaling and macrophage polarization Open
View article: Transcriptome sequencing and metabolome analysis reveal metabolic reprogramming of partial hepatectomy and extended hepatectomy
Transcriptome sequencing and metabolome analysis reveal metabolic reprogramming of partial hepatectomy and extended hepatectomy Open
Surgical resection remains a critical treatment option for many patients with primary and secondary hepatic neoplasms. Extended hepatectomy (eHx) may be required for some patients with large tumors, which may cause liver failure and indivi…
View article: The role of the complosome in health and disease
The role of the complosome in health and disease Open
The complement system is one of the immune system’s oldest defense mechanisms and is historically regarded as a liver-derived and serum-active innate immune system that ‘complements’ cell-mediated and antibody-mediated immune responses aga…
View article: Additional file 3 of Transcriptome sequencing and metabolome analysis reveal the metabolic reprogramming of partial hepatectomy and extended hepatectomy
Additional file 3 of Transcriptome sequencing and metabolome analysis reveal the metabolic reprogramming of partial hepatectomy and extended hepatectomy Open
Additional file 3: Table S2. Expression patterns of all 14,505 reserved genes in eHx vs. pHx.
View article: Additional file 5 of Transcriptome sequencing and metabolome analysis reveal the metabolic reprogramming of partial hepatectomy and extended hepatectomy
Additional file 5 of Transcriptome sequencing and metabolome analysis reveal the metabolic reprogramming of partial hepatectomy and extended hepatectomy Open
Additional file 5: Table S3. 1383 metabolites were filtered (variable coefficient ≥ 0.3) in all groups.