Shiyu Pang
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View article: The value of spectral CT quantitative parameters in predicting Ki-67 level in ovarian cancer
The value of spectral CT quantitative parameters in predicting Ki-67 level in ovarian cancer Open
Objective The objective of this study is to evaluate the predictive value of quantitative parameters from spectral CT for Ki-67 expression in ovarian cancer (OC). Methods Spectral CT imaging data from 39 patients with ovarian cancer by pat…
View article: Preoperative CT-based radiomics combined with AFP, PIVKA-II and other laboratory tests can be used to predict the pathological grade of hepatocellular carcinoma
Preoperative CT-based radiomics combined with AFP, PIVKA-II and other laboratory tests can be used to predict the pathological grade of hepatocellular carcinoma Open
Background To investigate how effectively clinical features and CT-based radiomics predict the pathological grade of hepatocellular carcinoma（HCC）. Methods We retrospectively analyzed 108 patients diagnosed with hepatocellular carcinoma wh…
View article: Chimeric <i>SFT2D2‐TBX19</i> Promotes Prostate Cancer Progression by Encoding TBX19‐202 Protein and Stabilizing Mitochondrial ATP Synthase through ATP5F1A Phosphorylation
Chimeric <i>SFT2D2‐TBX19</i> Promotes Prostate Cancer Progression by Encoding TBX19‐202 Protein and Stabilizing Mitochondrial ATP Synthase through ATP5F1A Phosphorylation Open
Specific chimeric RNAs and their products are consistently regarded as ideal tumor diagnostic markers and therapeutic targets. Chimeric RNAs can mediate tumor cell plasticity, neuroendocrine processes, polarization of tumor‐associated macr…
View article: O-GlcNAcylation regulation of RIPK1-dependent apoptosis dictates sensitivity to sunitinib in renal cell carcinoma
O-GlcNAcylation regulation of RIPK1-dependent apoptosis dictates sensitivity to sunitinib in renal cell carcinoma Open
Receptor interacting protein kinase 1 (RIPK1) has emerged as a key regulatory molecule that influences the balance between cell death and cell survival. Under external stress, RIPK1 determines whether a cell undergoes RIPK-dependent apopto…
View article: Bladder-cancer-derived exosomal circRNA_0013936 promotes suppressive immunity by up-regulating fatty acid transporter protein 2 and down-regulating receptor-interacting protein kinase 3 in PMN-MDSCs
Bladder-cancer-derived exosomal circRNA_0013936 promotes suppressive immunity by up-regulating fatty acid transporter protein 2 and down-regulating receptor-interacting protein kinase 3 in PMN-MDSCs Open
Background Polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) is one of the causes of tumor immune tolerance and failure of cancer immunotherapy. Here, we found that bladder cancer (BCa)-derived exosomal circRNA_0013936 could e…
View article: CircPPAP2B controls metastasis of clear cell renal cell carcinoma via HNRNPC-dependent alternative splicing and targeting the miR-182-5p/CYP1B1 axis
CircPPAP2B controls metastasis of clear cell renal cell carcinoma via HNRNPC-dependent alternative splicing and targeting the miR-182-5p/CYP1B1 axis Open
Background Renal cell carcinoma (RCC) is one of the most common malignant tumor worldwide. Metastasis is a leading case of cancer-related deaths of RCC. Circular RNAs (circRNAs), a class of noncoding RNAs, have emerged as important regulat…
View article: AIM2 is a novel biomarker for predicting prognosis and immunotherapy response of clear cell renal cell carcinoma
AIM2 is a novel biomarker for predicting prognosis and immunotherapy response of clear cell renal cell carcinoma Open
Background As an indispensable component of the inflammasome, absent in melanoma 2 (AIM2) plays an essential role in the initiation of the innate immune response, while its effects on clear cell renal cell carcinoma (ccRCC) still remain un…
View article: Synergy between FATP2 and RIPK3 pathways promotes PMN-MDSCs-potentiated suppressive immunity in bladder cancer
Synergy between FATP2 and RIPK3 pathways promotes PMN-MDSCs-potentiated suppressive immunity in bladder cancer Open
Background Polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) promote tumor immune tolerance and cause tumor immunotherapy failure. In this study, we found that high PMN-MDSCs infiltration, overexpressed fatty acid transporter …
View article: Predicative value of IFITM2 in renal clear cell carcinoma: IFITM2 is associated with lymphatic metastasis and poor clinical outcome
Predicative value of IFITM2 in renal clear cell carcinoma: IFITM2 is associated with lymphatic metastasis and poor clinical outcome Open
Renal clear cell carcinoma (ccRCC), is an inflammation-related malignancy with poor therapeutic outcome. Interferon-induced transmembrane protein 2 (IFITM2), an inflammation related gene, is reported to promote tumor progression via induci…
View article: Adrenal Myelolipoma with Adrenocortical Adenoma Presenting with Hypertension Only
Adrenal Myelolipoma with Adrenocortical Adenoma Presenting with Hypertension Only Open
Here, we present a case of a 25-year Chinese female who was diagnosed with non-functional adrenocortical adenoma containing myelolipoma with hypertension as the only symptom. Serum levels of cortisol, aldosterone, angiotensin I/II and reni…
View article: A modified method by differential adhesion and serum-free culture medium for enrichment of cancer stem cells
A modified method by differential adhesion and serum-free culture medium for enrichment of cancer stem cells Open
Trypsin-resistant cells showed specific CSCs characterizations. They were able to be isolated successfully with a modified method by a combination of differential adhesion method and SFM method.
View article: A greater number of dissected lymph nodes is associated with more favorable outcomes in bladder cancer treated by radical cystectomy: a meta-analysis
A greater number of dissected lymph nodes is associated with more favorable outcomes in bladder cancer treated by radical cystectomy: a meta-analysis Open
The optimal extent of lymph node dissection (LND) is currently not established, and the debate regarding the association between the number of dissected nodes and the outcomes of bladder cancer treated by radical cystectomy (RC) is still o…
View article: A modified method by differential adhesion for enrichment of bladder cancer stem cells
A modified method by differential adhesion for enrichment of bladder cancer stem cells Open
Trypsin-resistant cells displayed specific CSCs properties. Our study showed trypsin-resistant cells were isolated successfully with a modified method using a combination of differential adhesion method and SFM method.
View article: Characteristics of bladder transitional cell carcinoma with E-cadherin and N-cadherin double-negative expression
Characteristics of bladder transitional cell carcinoma with E-cadherin and N-cadherin double-negative expression Open
The aim of the present study was to examine the characteristics of bladder transitional cell carcinoma with E-cadherin and N-cadherin double-negative expression. An immunofluorescence assay was used to detect E-cadherin and N-cadherin expr…