Sixiu Huang
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View article: Origins, Dispersal, and Impact: Bidirectional Introgression Between Chinese and European Pig Populations (Adv. Sci. 22/2025)
Origins, Dispersal, and Impact: Bidirectional Introgression Between Chinese and European Pig Populations (Adv. Sci. 22/2025) Open
View article: Cross‐Species Insights into Trophoblast Invasion During Placentation Governed by Immune‐Featured Trophoblast Cells (Adv. Sci. 42/2024)
Cross‐Species Insights into Trophoblast Invasion During Placentation Governed by Immune‐Featured Trophoblast Cells (Adv. Sci. 42/2024) Open
Cross‐Species Insights into Trophoblast Invasion The image depicts the important roles of iTrophoblast in invasive placentation through the Chinese mythology “Hundred Birds Paying Homage to the Phoenix”. During placentation, iTrophoblast (…
View article: Supplementation of SkQ1 Increases Mouse In Vitro Oocyte Maturation and Subsequent Embryonic Development by Reducing Oxidative Stress
Supplementation of SkQ1 Increases Mouse In Vitro Oocyte Maturation and Subsequent Embryonic Development by Reducing Oxidative Stress Open
In vitro oocyte maturation (IVM) technology is important for assisted animal and human reproduction. However, the maturation rates and developmental potential of in vitro-matured oocytes are usually lower than those of in vivo-matured oocy…
View article: Porcine Granulosa-Cell-Derived Exosomes Enhance Oocyte Development: An In Vitro Study
Porcine Granulosa-Cell-Derived Exosomes Enhance Oocyte Development: An In Vitro Study Open
Recent studies have established that exosomes (EXs) derived from follicular fluid (FF) can promote oocyte development. However, the specific sources of these EXs and their regulatory mechanisms remain elusive. It is universally acknowledge…
View article: Multi-omic characterization of allele-specific regulatory variation in hybrid pigs
Multi-omic characterization of allele-specific regulatory variation in hybrid pigs Open
Genetic variation in the regulation of gene expression contributes substantially to phenotypic variation. Understanding how variation in DNA sequences and epigentic modifications leads to gene expression variation remains a challenging tas…
View article: WITHDRAWN: Genomic and Phenotypic Consequences of Bi-Directional Introgression Between Chinese and European Pig Breeds
WITHDRAWN: Genomic and Phenotypic Consequences of Bi-Directional Introgression Between Chinese and European Pig Breeds Open
Withdrawal Statement The authors have withdrawn this manuscript because [the results have been updated with new data and revised analyses]. Therefore, the authors do not wish this work to be cited as reference for the project. If you have …
View article: Genome-Wide Association Study of Body Conformation Traits in a Three-Way Crossbred Commercial Pig Population
Genome-Wide Association Study of Body Conformation Traits in a Three-Way Crossbred Commercial Pig Population Open
Body conformation is the most direct production index, which can fully reflect pig growth status and is closely related to critical economic traits. In this study, we conducted a genome-wide association study (GWAS) on body conformation tr…
View article: Progesterone and Androstenedione Are Important Follicular Fluid Factors Regulating Porcine Oocyte Maturation Quality
Progesterone and Androstenedione Are Important Follicular Fluid Factors Regulating Porcine Oocyte Maturation Quality Open
Oocytes matured in vitro are useful for assisted human and farm animal reproduction. However, the quality of in vitro matured oocytes is usually lower than that of in vivo matured oocytes, possibly due to the absence of some important sign…
View article: Interaction between Microbes and Host in Sow Vaginas in Early Pregnancy
Interaction between Microbes and Host in Sow Vaginas in Early Pregnancy Open
This work sheds light on the dynamics of the sow vaginal microbiotas in early pregnancy and its roles in pregnancy development. Furthermore, this study provides insight into the functional mechanisms of reproductive tract microbes by outli…
View article: Additional file 9 of Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation
Additional file 9 of Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation Open
Additional file 9: Table S5. Protein-protein interaction in clusters 1 and 2.
View article: Additional file 7 of Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation
Additional file 7 of Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation Open
Additional file 7: Table S3. Clustering of proteins in the uterine luminal fluid-Evs.
View article: Additional file 5 of Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation
Additional file 5 of Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation Open
Additional file 5: Table S1. The specific primers for qRT-PCR.
View article: Additional file 8 of Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation
Additional file 8 of Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation Open
Additional file 8: Table S4. GO enrichment and KEGG pathway analysis of proteins in clusters 1 and 2.
View article: Additional file 6 of Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation
Additional file 6 of Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation Open
Additional file 6: Table S2. Relative abundance of proteins in the uterine luminal fluid-Evs.
View article: Additional file 11 of Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation
Additional file 11 of Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation Open
Additional file 11: Table S7. GO enrichment and KEGG pathway analysis of differentially abundant proteins in PTR cells treated with ULF-Evs.
View article: Additional file 10 of Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation
Additional file 10 of Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation Open
Additional file 10: Table S6. Differentially abundant proteins in PTR cells treated with ULF-Evs.
View article: Corrigendum: Global Transcriptomic Analyses Reveal Genes Involved in Conceptus Development During the Implantation Stages in Pigs
Corrigendum: Global Transcriptomic Analyses Reveal Genes Involved in Conceptus Development During the Implantation Stages in Pigs Open
In the original article, there was a mistake in Figure 8 as published. The images of siRNA-NC and siRNA-PAG-2 in Figure 8D were placed upside down. We found that the error was caused by our carelessness in typesetting. The corrected Figure…
View article: Identification and Comparative Analysis of Long Non-coding RNAs in High- and Low-Fecundity Goat Ovaries During Estrus
Identification and Comparative Analysis of Long Non-coding RNAs in High- and Low-Fecundity Goat Ovaries During Estrus Open
The ovary is the most important reproductive organ in goats and directly affects the fecundity. Long non-coding RNAs (lncRNAs) are involved in the biological process of oocyte maturation. However, in the context of reproduction in goats, f…
View article: Weighted Single-Step GWAS Identified Candidate Genes Associated with Growth Traits in a Duroc Pig Population
Weighted Single-Step GWAS Identified Candidate Genes Associated with Growth Traits in a Duroc Pig Population Open
Growth traits are important economic traits of pigs that are controlled by several major genes and multiple minor genes. To better understand the genetic architecture of growth traits, we performed a weighted single-step genome-wide associ…
View article: Additional file 4 of Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs
Additional file 4 of Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs Open
Additional file 4: Table S4. qPCR primer and probe sequence information.
View article: Additional file 7 of Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs
Additional file 7 of Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs Open
Additional file 7: Table S7. KEGG and GO Enrichment Analysis for significant CNVRs gene set by KOBAS.
View article: Additional file 6 of Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs
Additional file 6 of Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs Open
Additional file 6: Table S6. Information of genes in the significant CNVRs.
View article: Additional file 1 of Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs
Additional file 1 of Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs Open
Additional file 1: Table S1. Overview of CNVRs for two Duroc populations.
View article: Additional file 2 of Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs
Additional file 2 of Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs Open
Additional file 2: Table S2. Information of CNVRs shared by two Duroc populations.
View article: Additional file 3 of Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs
Additional file 3 of Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs Open
Additional file 3: Table S3. Identified CNVRs compared with previous studies.
View article: Expression Pattern of Seminal Plasma Extracellular Vesicle Small RNAs in Boar Semen
Expression Pattern of Seminal Plasma Extracellular Vesicle Small RNAs in Boar Semen Open
Extracellular vesicles (EVs) regulate multiple physiological processes. Seminal plasma contains numerous EVs that may deliver functional molecules such as small RNAs (sRNAs) to the sperm. However, the RNA profiles in the boar seminal plasm…
View article: Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs
Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs Open
Background: In the process of pig breeding, the average daily gain (ADG), days to 100 kg (AGE), and backfat thickness (BFT) are directly related to growth rate and fatness. However, the genetic mechanisms involved are not well understood. …
View article: Murine Thigh Microdialysis to Evaluate the Pharmacokinetic/Pharmacodynamic Integration of Cefquinome Against Actinobacillus pleuropneumoniae
Murine Thigh Microdialysis to Evaluate the Pharmacokinetic/Pharmacodynamic Integration of Cefquinome Against Actinobacillus pleuropneumoniae Open
This study aimed to explore the application of microdialysis in pharmacokinetic (PK)/pharmacodynamic (PD) integration of cefquinome against Actinobacillus pleuropneumoniae. After the A. pleuropneumoniae population reached 10<…
View article: Deep-Sequencing Identification of MicroRNA Biomarkers in Serum Exosomes for Early Pig Pregnancy
Deep-Sequencing Identification of MicroRNA Biomarkers in Serum Exosomes for Early Pig Pregnancy Open
Early pregnancy diagnosis in sows can significantly improve the efficiency of pig industry. Exosomes are membrane-covered nanovesicles that can transport microRNAs (miRNAs) and other molecular signals between cells. In other species, serum…