Si‐Xue Cheng
YOU?
Author Swipe
View article: Enhancing targeted cancer therapy through multiple drug delivery by silk peptide nanoparticles
Enhancing targeted cancer therapy through multiple drug delivery by silk peptide nanoparticles Open
Targeted therapy drugs exert an essential role in precision therapy in cancer treatments. However, their therapeutic efficiency is greatly limited by the poor water solubility and low bioavailability. Herein, by using an epidermal growth f…
View article: Utilizing Hairy Hollow Conjugated Microporous Polymers and Native Enzymes for Precise Aerobic Photocatalysis Under Near‐Infrared Wavelengths
Utilizing Hairy Hollow Conjugated Microporous Polymers and Native Enzymes for Precise Aerobic Photocatalysis Under Near‐Infrared Wavelengths Open
Utilizing photoregenerated cofactors in conjunction with enzymes in a sequential manner presents an effective approach for the synthesis of targeted compounds in gentle reaction conditions. Nevertheless, the integration of enzymes and phot…
View article: History, present, and future of polymer science at Wuhan University
History, present, and future of polymer science at Wuhan University Open
As an integral part of the College of Chemistry and Molecular Sciences at Wuhan University (WHU Chemistry), the Department of Polymer Science at Wuhan University (WHU Polymer) originated from the disciplines of Organic Chemistry and Polyme…
View article: A Multifunctional Delivery System for Remodulating Cell Behaviors of Circulating Malignant Cells to Prevent Cell Fusion
A Multifunctional Delivery System for Remodulating Cell Behaviors of Circulating Malignant Cells to Prevent Cell Fusion Open
Cell fusion plays a critical role in cancer progression and metastasis. However, effective modulation of the cell fusion behavior and timely evaluation on the cell fusion to provide accurate information for personalized therapy are facing …
View article: Codelivery of HBx-siRNA and Plasmid Encoding IL-12 for Inhibition of Hepatitis B Virus and Reactivation of Antiviral Immunity
Codelivery of HBx-siRNA and Plasmid Encoding IL-12 for Inhibition of Hepatitis B Virus and Reactivation of Antiviral Immunity Open
Chronic hepatitis B is a critical cause of many serious liver diseases such as hepatocellular carcinoma (HCC). The main challenges in hepatitis B treatment include the rebound of hepatitis B virus (HBV)-related antigen levels after drug wi…
View article: Functional Tumor Targeting Nano‐Systems for Reprogramming Circulating Tumor Cells with In Situ Evaluation on Therapeutic Efficiency at the Single‐Cell Level
Functional Tumor Targeting Nano‐Systems for Reprogramming Circulating Tumor Cells with In Situ Evaluation on Therapeutic Efficiency at the Single‐Cell Level Open
Tumor heterogeneity is primarily responsible for treatment resistance and cancer relapses. Being critically important to address this issue, the timely evaluation of the appropriateness of therapeutic actions at the single‐cell level is st…
View article: Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies
Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies Open
Global alterations in the metabolic network provide substances and energy to support tumor progression. To fuel these metabolic processes, extracellular matrix (ECM) plays a dominant role in supporting the mass transport and providing esse…
View article: Vascular disrupting agent induced aggregation of gold nanoparticles for photothermally enhanced tumor vascular disruption
Vascular disrupting agent induced aggregation of gold nanoparticles for photothermally enhanced tumor vascular disruption Open
Vascular disrupting agent mediated gold nanoparticles assembly for tumor vascular disruption with photothermal effect.
View article: An RGB-emitting molecular cocktail for the detection of bacterial fingerprints
An RGB-emitting molecular cocktail for the detection of bacterial fingerprints Open
A technique named the Microcolor system was developed to detect microbes and diagnose diseases based on changes in microbiota signatures.
View article: Biomedical Materials: Engineered Bacterial Bioreactor for Tumor Therapy via Fenton‐Like Reaction with Localized H<sub>2</sub>O<sub>2</sub> Generation (Adv. Mater. 16/2019)
Biomedical Materials: Engineered Bacterial Bioreactor for Tumor Therapy via Fenton‐Like Reaction with Localized H<sub>2</sub>O<sub>2</sub> Generation (Adv. Mater. 16/2019) Open
In article number 1808278, Xian-Zheng Zhang and co-workers develop an integrative bioreactor based on engineered bacteria for tumor therapy. This bioreactor displays bacterial tumor tropism and spontaneously supplies localized H2O2 for a t…
View article: Tumor Targeting: Programmed Nanococktail for Intracellular Cascade Reaction Regulating Self‐Synergistic Tumor Targeting Therapy (Small 6/2016)
Tumor Targeting: Programmed Nanococktail for Intracellular Cascade Reaction Regulating Self‐Synergistic Tumor Targeting Therapy (Small 6/2016) Open
An improved antitumor therapy can be achieved by rationally designing an intelligent nanomedicine with programmed functions to specifically eliminate tumors while leaving healthy tissues untouched. On page 733, X.-Z. Zhang and co-workers d…
View article: Self-defensive nano-assemblies from camptothecin-based antitumor drugs
Self-defensive nano-assemblies from camptothecin-based antitumor drugs Open
Camptothecin (CPT)-based drugs always undergo the reversible, pH-dependent lactone ring-opening reaction, yielding the inactive but toxic carboxylate form. Self-assembly strategy provides an effective route for preserving their bio-stabili…