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View article: A CASE REPORT OF SUCCESSFUL STEROID TREATMENT IN INFANT WITH EXTRAHEPATIC CHOLESTASIS
A CASE REPORT OF SUCCESSFUL STEROID TREATMENT IN INFANT WITH EXTRAHEPATIC CHOLESTASIS Open
Background: Cholestatic jaundice in infants is a significant healthcare challenge, particularly in regions where access to surgical intervention and liver transplantation is limited. An immunologic mechanism underlies the pathogenesis of b…
View article: Primary Sclerosing Cholangitis in a Child: A Rare Case Report
Primary Sclerosing Cholangitis in a Child: A Rare Case Report Open
Primary sclerosing cholangitis (PSC) is a chronic inflammation of the bile ducts that leads to progressive narrowing, ultimately resulting in liver cirrhosis. A 10-year-old boy presented with jaundice, abdominal pain, nausea, weight loss, …
View article: Ascites and neonatal cholestasis: a successful steroid therapy
Ascites and neonatal cholestasis: a successful steroid therapy Open
Introduction. Neonatal cholestasis is caused by surgical or medical conditions, and its management must be prompt to improve patient outcomes. Case presentation. A 3-month-old baby boy presented with complaints of prolonged jaundice and ac…
View article: LIVER CANCER ASSOCIATED WITH HEPATITIS B VIRUS INFECTION IN A CHILD: A CASE REPORT
LIVER CANCER ASSOCIATED WITH HEPATITIS B VIRUS INFECTION IN A CHILD: A CASE REPORT Open
Background: Two-thirds of primary liver tumors in children are malignant. Hepatoblastoma (HBL) accounts for 40-60 percent of pediatric liver tumors and is the most common malignant liver tumor. Hepatocellular Carcinoma (HCC) is the second …
View article: Late Referral of Biliary Atresia and Poor Clinical Outcomes
Late Referral of Biliary Atresia and Poor Clinical Outcomes Open
These findings emphasize the urgent need for earlier detection and referral to improve outcomes in infants with BA.
View article: Varied Characteristics of Recovered Patients with Biliary Atresia
Varied Characteristics of Recovered Patients with Biliary Atresia Open
These findings highlight the importance of early diagnosis and intervention in improving BA outcomes. Future research should focus on optimizing treatment strategies to enhance long-term survival.
View article: Intracranial hemorrhage as a rare complication of cholestasis: a case report
Intracranial hemorrhage as a rare complication of cholestasis: a case report Open
Cholestasis, characterized by impaired bile secretion and flow, predisposes infants to vitamin K deficiency and consequent coagulopathies, leading to severe bleeding complications such as intracranial hemorrhage (ICH). This case report des…
View article: <b>Hepatitis B and Hepatocellular Carcinoma: A Case Report and Literature Review</b>
<b>Hepatitis B and Hepatocellular Carcinoma: A Case Report and Literature Review</b> Open
Introduction: Current data estimates that over 90% of primary liver tumors are hepatocellular carcinomas (HCC), a type of malignant hepatocyte tumor. Viral hepatitis B is particularly associated with HCC. Early detection of chronic hepatit…
View article: Infant with biliary atresia: a case report
Infant with biliary atresia: a case report Open
Background: In children, biliary atresia (BA) is the most frequent cause of liver transplantation. Cholestasis, an early sign of biliary atresia, is rarely identified by primary care physicians as it is often mistaken for physiological jau…
View article: Dramatic Extrahepatic Cholestasis Improvement after Steroid Therapy
Dramatic Extrahepatic Cholestasis Improvement after Steroid Therapy Open
Biliary atresia remains a health concern and the leading cause of liver transplantation despite the establishment of Kasai surgery. This case report describes an infant with extrahepatic cholestasis leading to biliary atresia that improved…
View article: Challenges in Managing Portal Hypertension and Fibrosis in a Case of Biliary Atresia Post-Kasai Procedure—Implications for Early Detection and Long-Term Care
Challenges in Managing Portal Hypertension and Fibrosis in a Case of Biliary Atresia Post-Kasai Procedure—Implications for Early Detection and Long-Term Care Open
Biliary atresia frequently causes portal hypertension, resulting in significant morbidity and mortality. Elevated portal pressure can be detected as early as during a Kasai procedure. Pediatric portal hypertension is the primary cause of v…
View article: Socialization of stool color card for early detection of biliary atresia among healthcare professionals in Primary Healthcare facilities in Probolinggo
Socialization of stool color card for early detection of biliary atresia among healthcare professionals in Primary Healthcare facilities in Probolinggo Open
Background: Biliary Atresia (BA) is an idiopathic progressive fibro obliterative disease affecting the extrahepatic biliary duct with clinical manifestations of biliary obstruction in the neonatal period. Infants with BA are characterized …
View article: Delayed Admission in Neonatal Cholestasis
Delayed Admission in Neonatal Cholestasis Open
Delayed diagnosis of cholestasis in neonates remains a problem. Cholestatic jaundice is a pathological condition that requires immediate treatment, such as biliary atresia. This study aims to analyze the characteristics of infants with cho…
View article: Ascites of unknown origin in infant: a rare case report
Ascites of unknown origin in infant: a rare case report Open
Introduction. Ascites of unknown origin in infants are rare and diagnostically challenging. However, it can be associated with a poor prognosis if it is not treated promptly. Case presentation. A 3-month-old boy infant was admitted to the …
View article: Biliary atresia and situs inversus in infant: a rare case report
Biliary atresia and situs inversus in infant: a rare case report Open
Background. Biliary atresia is the leading cause of liver transplantation in children. It is associated with other congenital anomalies. The presentation of biliary atresia with situs inversus is a rare case. Case presentation. A 2-month-o…
View article: Correlation of aspartate aminotransferase-to-platelet ratio index with the METAVIR index in infantile cholestasis
Correlation of aspartate aminotransferase-to-platelet ratio index with the METAVIR index in infantile cholestasis Open
Background: Neonatal cholestasis affects 1 in 2,500 term infants, biliary atresia being the most common and severe cause. Histopathological examination of liver biopsy remains the gold standard for diagnosis, the METAVIR index determining …
View article: Hepatoblastoma in Infant: A Rare Case Report and Literature Review
Hepatoblastoma in Infant: A Rare Case Report and Literature Review Open
Introduction: Hepatoblastoma is the most common liver malignancy in children. Hepatoblastoma in infants is rare and usually presents as an abdominal mass without specific symptoms. Diagnosis is difficult, supported by adequate imaging moda…
View article: Successful Steroid Therapy in a Child with Suspected Autoimmune Hepatitis
Successful Steroid Therapy in a Child with Suspected Autoimmune Hepatitis Open
Introduction: Autoimmune Hepatitis (AIH) is an unexplained cause of chronic and progressive liver inflammation. The incidence of AIH is about 4.82/per 100,000 people in Korea, but based on global research the incidence is increasing and it…
View article: Caroli's Disease in a Child: A Rare Case Report
Caroli's Disease in a Child: A Rare Case Report Open
Introduction: Caroli's disease is a rare hereditary condition. It is characterized by segmental dilatation of the large intrahepatic bile duct with a cyst-like appearance. Caroli's disease is often found on typical imaging without specific…
View article: Seeking Liver Fibrosis in Biliary Atresia using De Ritis Ratio
Seeking Liver Fibrosis in Biliary Atresia using De Ritis Ratio Open
Introduction: Biliary atresia (BA) is a rare and devastating pediatric liver disorder characterized by progressive obstruction or absence of the extrahepatic bile ducts within infants. One crucial aspect of understanding the disease proces…
View article: Effectiveness of oral methylprednisolone as adjuvant therapy for clinical improvement, biochemical markers, and inflammation in infants with cholestasis
Effectiveness of oral methylprednisolone as adjuvant therapy for clinical improvement, biochemical markers, and inflammation in infants with cholestasis Open
Methylprednisolone was efficacious in reducing 2-week bilirubin levels. These results support the hypothesis that the immunological process is involved in cholestasis. Further studies with larger sample sizes are needed to confirm the bile…
View article: Choledochal cyst type I in infant: a case report
Choledochal cyst type I in infant: a case report Open
Choledochal cysts are rare congenital anomalies characterized by dilatation of the bile ducts. The most frequent subtype of choledochal cyst is type I, which has fusiform dilatation of the common bile duct and poses significant challenges …
View article: Risk factors for portal hypertension in children with biliary atresia
Risk factors for portal hypertension in children with biliary atresia Open
Introduction: Biliary atresia is a hepatobiliary disease which frequently results in portal hypertension.Objectives: To analyse the risk factors for portal hypertension in children with biliary atresia.Method: A case-controlled study was p…
View article: Steroid therapy in extrahepatic cholestasis suggestive of biliary atresia: A case report
Steroid therapy in extrahepatic cholestasis suggestive of biliary atresia: A case report Open
Background: Biliary atresia is a fibroinflammatory disease obstructing the extrahepatic biliary system. Biliary atresia is the leading cause of cholestasis in infants and the cause of end-stage liver disease in the first two years of life.…
View article: Neutrophil to Lymphocyte Ratio, is it A Good Marker for Determining Degree of Fibrosis in Biliary Atresia?
Neutrophil to Lymphocyte Ratio, is it A Good Marker for Determining Degree of Fibrosis in Biliary Atresia? Open
Biliary atresia (BA) can progress to liver fibrosis and cirrhosis. The Neutrophil-to-lymphocyte ratio (NLR) integrates two immune pathways - neutrophils, which illustrate continuous inflammation, and lymphocytes, which illustrate the regul…
View article: DIFFERENCES OF BIRTH WEIGHT AND ONSET OF ACHOLIC STOOL BETWEEN EXTRAHEPATIC AND INTRAHEPATIC CHOLESTASIS
DIFFERENCES OF BIRTH WEIGHT AND ONSET OF ACHOLIC STOOL BETWEEN EXTRAHEPATIC AND INTRAHEPATIC CHOLESTASIS Open
Background: Biliary atresia (extrahepatic cholestasis) and neonatal hepatitis (intrahepatic cholestasis) are two main causes of cholestasis. It is important to distinguish the type of cholestasis for determine management. Patient with intr…
View article: Quality of Life of Parents and Patients with Biliary Atresia in Native Liver
Quality of Life of Parents and Patients with Biliary Atresia in Native Liver Open
Children with chronic conditions such as biliary atresia may experience several issues that affect their quality of life (QoL). Childhood chronic disease impacts family members and leads to family health impairment. Objective: This study a…
View article: Accuracy of 2-phase abdominal ultrasound for diagnosing biliary atresia
Accuracy of 2-phase abdominal ultrasound for diagnosing biliary atresia Open
Background: Biliary atresia is a dangerous neonatal disorder characterized by an inflammatory and fibrotic obliteration of the extrahepatic biliary tree, which results in progressive hepatic failure and, if ignored, death from end-stage li…
View article: Primary Healthcare Providers' Knowledge on the Early Detection of Biliary Atresia
Primary Healthcare Providers' Knowledge on the Early Detection of Biliary Atresia Open
Highlights:1. An evaluation is necessary to verify that the knowledge of healthcare providers is sufficient for the early detection of biliary atresia.2. It is crucial to promote education on prolonged jaundice to ensure early detection of…
View article: Management of Neonatal Jaundice during Initial Health Care Visit
Management of Neonatal Jaundice during Initial Health Care Visit Open
Backgrounds: Cholestasis is a bile flow disorder resulting in liver bile retention. It is characterized by intrahepatic (IH) and extrahepatic (EH) cholestasis. Health workers are strategically placed to provide correct information in manag…