Skyler Kessler
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View article: B Cell–Mediated Antigen Presentation through MHC Class II Is Dispensable for Atherosclerosis Progression
B Cell–Mediated Antigen Presentation through MHC Class II Is Dispensable for Atherosclerosis Progression Open
Depletion of B cells attenuates plaque development and modulates T cell responses in mouse models of atherosclerosis, suggesting that Ag presentation by B cells may promote disease progression. Thus, we set out to determine the role of B c…
View article: Thermoneutrality but Not UCP1 Deficiency Suppresses Monocyte Mobilization Into Blood
Thermoneutrality but Not UCP1 Deficiency Suppresses Monocyte Mobilization Into Blood Open
Rationale: Ambient temperature is a risk factor for cardiovascular disease. Cold weather increases cardiovascular events, but paradoxically, cold exposure is metabolically protective because of UCP1 (uncoupling protein 1)-dependent thermog…