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View article: Ensemble Approaches for Robust and Generalizable Short-Term Forecasts of Dengue Fever. A retrospective and prospective evaluation study in over 180 locations around the world
Ensemble Approaches for Robust and Generalizable Short-Term Forecasts of Dengue Fever. A retrospective and prospective evaluation study in over 180 locations around the world Open
Dengue fever, a tropical vector-borne disease, is a leading cause of hospitalization and death in many parts of the world, especially in Asia and Latin America. In places where timely and accurate dengue activity surveillance is available,…
View article: Polyphenolic Platform Ameliorated Sanshool for Skin Photoprotection
Polyphenolic Platform Ameliorated Sanshool for Skin Photoprotection Open
Natural evolution has nurtured a series of active molecules that play vital roles in physiological systems, but their further applications have been severely limited by rapid deactivation, short cycle time, and potential toxicity after iso…
View article: Short-term risk and long-term incidence rate of infection and malignancy with IL-17 and IL-23 inhibitors in adult patients with psoriasis and psoriatic arthritis: a systematic review and meta-analysis
Short-term risk and long-term incidence rate of infection and malignancy with IL-17 and IL-23 inhibitors in adult patients with psoriasis and psoriatic arthritis: a systematic review and meta-analysis Open
The risk of infection and malignancy may be a concern for patients with psoriasis receiving interleukin (IL)-17 and IL-23 inhibitors, particularly with long-term treatments. We aimed to estimate the short-term risks and long-term incidence…
View article: Oral small-molecule tyrosine kinase 2 and phosphodiesterase 4 inhibitors in plaque psoriasis: a network meta-analysis
Oral small-molecule tyrosine kinase 2 and phosphodiesterase 4 inhibitors in plaque psoriasis: a network meta-analysis Open
Background Orally administered small-molecule drugs including tyrosine kinase 2 (TYK2) inhibitors and phosphodiesterase 4 (PDE4) inhibitors are new candidates for systemic therapy in plaque psoriasis. However, no previous articles evaluate…
View article: Upadacitinib in the Treatment of Atopic Dermatitis: A Systematic Review and Meta‐Analysis
Upadacitinib in the Treatment of Atopic Dermatitis: A Systematic Review and Meta‐Analysis Open
Background . The pathogenesis of atopic dermatitis (AD) is associated with proinflammatory cytokines and the JAK/STAT signaling pathway. Upadacitinib, an approved oral JAK1 inhibitor, has been investigated in some clinical trials and obser…
View article: The effects of photobiomodulation therapy on inflammatory mediators, immune infiltration, and angiogenesis in a mouse model of rosacea
The effects of photobiomodulation therapy on inflammatory mediators, immune infiltration, and angiogenesis in a mouse model of rosacea Open
This investigation suggested that PBMT can improve the rosacea condition by regulating key inflammatory mediators and dysregulating immune infiltration and angiogenesis.