Explanipedia

Synthetic computed tomography from magnetic resonance imaging: An editorial on deep learning approaches for hip and knee image translation Open

Atif Abedeen, Richard Smith, Michael T. Hirschmann, Ayoosh Pareek · 2025

This editorial provides a concise overview of synthetic computed tomography (CT) generation from magnetic resonance imaging (MRI) for musculoskeletal care, with a focus on hip and knee applications. We outline why interest in this area is …

Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer Open

Hui Zhang, Tao Liu, Zhen Zhang, Samuel Payne, Bai Zhang , et al. · 2025

Incidencia de COVID-19 en pacientes con cáncer del HIGA Alende, Mar del Plata, Argentina, 2020-2021 Open

Sebastian Bienaime, Christian Ballejo, Tamara Ricardo, Juan Ignacio Irassar, Gabriel Antonio Amezqueta , et al. · 2025

Introduction: COVID-19 differentially affected individuals with chronic diseases such as cancer, with greater severity and mortality than the general population. Objectives: Estimate the incidence of infection, hospitalization and fatality…

Correction: Nutritional markers and proteome in patients undergoing treatment for pulmonary tuberculosis differ by geographic region Open

Leah G. Jarlsberg, Komal Kedia, Jason Wendler, Aaron Wright, Paul Piehowski , et al. · 2025

[This corrects the article DOI: 10.1371/journal.pone.0250586.].

Integration of structural modeling and CADD scores improve variant classification for CFH SCRs 5-18 Open

Cobey J. H. Donelson, Héctor Martín Merinero, Seth J. Welsh, Santiago Rodrı́guez de Córdoba, Richard Smith , et al. · 2025

Interpretable machine learning models classify minerals via spectroscopy Open

Richard Smith, Tyler L. Spano, Marshall McDonnell, Lance Drane, Ian Gibbs , et al. · 2025

Deciphering ApoE Genotype-Driven Proteomic and Lipidomic Alterations in Alzheimer’s Disease Across Distinct Brain Regions Open

Melanie T. Odenkirk, Xueyun Zheng, Jennifer Kyle, Kelly G. Stratton, Carrie Nicora , et al. · 2025

Alzheimer's disease (AD) is a neurodegenerative disease with a complex etiology influenced by confounding factors such as genetic polymorphisms, age, sex, and race. Traditionally, AD research has not prioritized these influences, resulting…

Robust collection and processing for label-free single voxel proteomics Open

Reta Birhanu Kitata, Marija Veličković, Zhangyang Xu, Rui Zhao, David Scholten , et al. · 2025

With advanced mass spectrometry (MS)-based proteomics, genome-scale proteome coverage can be achieved from bulk tissues. However, such bulk measurement lacks spatial resolution and obscures tissue heterogeneity, precluding proteome mapping…

Data for EMSL Project 46206 from December 2018 Open

Karin Rodland, Richard Smith, David Camp, Scott Baker, Weijun Qian , et al. · 2024

Data for EMSL Project 47643 from January 2020 Open

Karin Rodland, Karin Rodland, Richard Smith, Richard Smith, David Camp , et al. · 2024

Data for EMSL Project 47643 from October 2021 Open

Karin Rodland, Karin Rodland, Richard Smith, Richard Smith, David Camp , et al. · 2024

Evaluation of a Reference-Free Collision Cross Section Calibration Strategy for Proteomics Using SLIM-Based High-Resolution Ion Mobility Spectrometry–Mass Spectrometry Open

Dylan H. Ross, Jung Yun Lee, Yuqian Gao, Adam Hollerbach, Aivett Bilbao Pena , et al. · 2024

Ion mobility spectrometry (IMS) is a gas-phase analytical technique that separates ions with different sizes and shapes and is compatible with mass spectrometry (MS) to provide an additional separation dimension. The rapid nature of the IM…

Data for EMSL Project 48666 from July 2020 Open

Karin Rodland, Anil Shukla, Richard Smith, David Camp, Rui Zhao , et al. · 2024

Data for EMSL Project 50076 from August 2020 Open

Richard Smith, Tom Metz, Kristin Burnum-Johnson, Carrie Nicora, Paul Piehowski , et al. · 2024

Proteogenomic characterization of difficult-to-treat breast cancer with tumor cells enriched through laser microdissection Open

Praveen Kumar, Xiaoying Lin, Tao Liu, Lori A. Sturtz, Marina Gritsenko , et al. · 2024

Background Breast cancer (BC) is the most commonly diagnosed cancer and the leading cause of cancer death among women globally. Despite advances, there is considerable variation in clinical outcomes for patients with non-luminal A tumors, …

Comprehensive proteogenomic characterization of rare kidney tumors Open

Ginny Xiaohe Li, Lijun Chen, Yi Hsiao, Rahul Mannan, Yuping Zhang , et al. · 2024

Non-clear cell renal cell carcinomas (non-ccRCCs) encompass diverse malignant and benign tumors. Refinement of differential diagnosis biomarkers, markers for early prognosis of aggressive disease, and therapeutic targets to complement immu…

A compendium of multi-omics data illuminating host responses to lethal human virus infections Open

Amie J. Eisfeld, Lindsey Anderson, Shufang Fan, Kevin Walters, Peter Halfmann , et al. · 2024

Computational tools and algorithms for ion mobility spectrometry‐mass spectrometry Open

Dylan H. Ross, Harsh Bhotika, Xueyun Zheng, Richard Smith, Kristin Burnum-Johnson , et al. · 2024

Ion mobility spectrometry‐mass spectrometry (IMS‐MS or IM‐MS) is a powerful analytical technique that combines the gas‐phase separation capabilities of IM with the identification and quantification capabilities of MS. IM‐MS can differentia…

Mobility Selective Ion Soft-Landing and Characterization Enabled Using Structures for Lossless Ion Manipulation Open

Jung Yun Lee, Ailin Li, Venkateshkumar Prabhakaran, Xin Zhang, Christopher Harrilal , et al. · 2024

While conventional ion-soft landing uses the mass-to-charge (m/z) ratio to achieve molecular selection for deposition, here we demonstrate the use of Structures for Lossless Ion Manipulation (SLIM) for mobility-based ion sele…

Editorial Board: Proteomics 3–4'24 Open

Andrew J. Link, Christoph H. Borchers, Canada Carapito, Yu‐Ju Chen, Taiwan Maxey , et al. · 2024

Deciphering ApoE Genotype-Driven Proteomic and Lipidomic Alterations in Alzheimer’s Disease Across Distinct Brain Regions Open

Melanie T. Odenkirk, Xueyun Zheng, Jennifer Kyle, Kelly G. Stratton, Carrie Nicora , et al. · 2024

Alzheimer's disease (AD) is a neurodegenerative disease with a complex etiology influenced by confounding factors such as genetic polymorphisms, age, sex, and race. Traditionally, AD research has not prioritized these influences, resulting…

Accumulation of Large Ion Populations with High Ion Densities and Effects Due to Space Charge in Traveling Wave-Based Structures for Lossless Ion Manipulations (SLIM) IMS-MS Open

Pearl Kwantwi-Barima, Sandilya Garimella, Isaac Attah, Xueyun Zheng, Yehia Ibrahim , et al. · 2024

The accumulation of very large ion populations in traveling wave (TW)-based Structures for Lossless ion Manipulations (SLIM) has been studied to better understand aspects of "in-SLIM" ion accumulation, and particularly its use in conjuncti…