Smiti Nanda
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View article: Evaluation of long-term clinical outcomes among PPIUCD users at six medical college hospitals
Evaluation of long-term clinical outcomes among PPIUCD users at six medical college hospitals Open
Background: Postpartum IUCDs are becoming increasingly popular in low-income countries, but there are few studies addressing long-term outcomes. Methods: A prospective observational study conducted in six tertiary care hospitals across Ind…
View article: Screening of High and Low-risk Human Papillomavirus Variants in Cervical Cancer Patients by Polymerase Chain Reaction: A Cross-sectional Study
Screening of High and Low-risk Human Papillomavirus Variants in Cervical Cancer Patients by Polymerase Chain Reaction: A Cross-sectional Study Open
Introduction: Cervical cancer is the second most common gynaecological malignancy worldwide. Persistent Human Papillomavirus (HPV) infection is the principal risk factor leading to cervical carcinogenesis and causes a large number of casua…
View article: Pregnancy with heart disease: Fetomaternal outcome: A retrospective analysis from a tertiary care teaching hospital in Northern India
Pregnancy with heart disease: Fetomaternal outcome: A retrospective analysis from a tertiary care teaching hospital in Northern India Open
Background: Heart diseases are the most significant non-obstetrical causes of maternal deaths, accounting for up to 15% of all cases. The present retrospective analysis is an attempt to assess the spectrum and impact of cardiac diseases on…
View article: Pregnancy with heart disease: Fetomaternal outcome: A retrospective analysis from a tertiary care teaching hospital in Northern India
Pregnancy with heart disease: Fetomaternal outcome: A retrospective analysis from a tertiary care teaching hospital in Northern India Open
Background: Heart diseases are the most significant non-obstetrical causes of maternal deaths, accounting for up to 15% of all cases. The present retrospective analysis is an attempt to assess the spectrum and impact of cardiac diseases on…
View article: Study of Gender-based Changes in P53 in Preeclampsia
Study of Gender-based Changes in P53 in Preeclampsia Open
It aims to compare the levels of p53 in maternal and umbilical cord venous samples of healthy pregnant and preeclamptics. Background: Preeclampsia is a leading cause of both maternal morbidity and neonatal mortality. The etiology and patho…
View article: COVID-19 suspicion and diagnosis in pregnancy: A big conundrum!
COVID-19 suspicion and diagnosis in pregnancy: A big conundrum! Open
A BSTRACT Introduction: This article aims to discuss all the challenges faced in the diagnosis of coronavirus disease 2019 (COVID-19) in pregnancy, isolation of suspected and positive patients, their management, and the strategies to preve…
View article: Fertility Awareness and its Association with Socio-demographic and Reproductive Variables among Women Seeking Fertility Treatment: A Cross-sectional Study
Fertility Awareness and its Association with Socio-demographic and Reproductive Variables among Women Seeking Fertility Treatment: A Cross-sectional Study Open
Introduction: In the last decade, there was a substantial reduction in fertility rates in Indian women. Despite a high burden of infertility, Fertility Awareness (FA) among people of reproductive age group is generally poor. Infertility is…
View article: Maternal and neonatal outcome in pregnancy with previous lower segment caesarean section undergoing trial of scar
Maternal and neonatal outcome in pregnancy with previous lower segment caesarean section undergoing trial of scar Open
Background: Women with previous LSCS often have to make a decision about mode of delivery of their second baby. As the rate of caesarean section is continuously increasing, vaginal birth after caesarean section (VBAC) is a good strategy to…
View article: Role of Vitamin D in Polycystic Ovarian Syndrome Patients
Role of Vitamin D in Polycystic Ovarian Syndrome Patients Open
Background: Polycystic Ovary Syndrome (PCOS), common cause of ovarian dysfunction. Vitamin D plays a physiologic role in reproduction including ovarian follicular development and luteinisation and its role in PCOS is not very clear. Aim an…
View article: Bladder hematoma as an unusual cause or consequence of obstructed labour
Bladder hematoma as an unusual cause or consequence of obstructed labour Open
Bladder hematoma is a rare complication but also an unusual mechanical cause of obstructed labour, whose incidence in India is 1-2%. The most common reason for intraluminal urinary bladder hematoma is trauma, but it can occur with cystitis…
View article: Challenges with Takayasu arteritis in pregnancy: a case report
Challenges with Takayasu arteritis in pregnancy: a case report Open
Takayasu’s arteritis (TA) is a rare, chronic, inflammatory, large vessel vasculitis (LVV) of unknown etiology characterized by narrowing, occlusion, and aneurysms of systemic and pulmonary arteries affecting especially the aorta and its br…
View article: A prospective study to evaluate the role of maternal thrombocytopenia on maternal and fetal outcome
A prospective study to evaluate the role of maternal thrombocytopenia on maternal and fetal outcome Open
Introduction: Thrombocytopenia is a very common finding in pregnancy, occurring in approximately 10% of women and it is the second most common hematological abnormality during pregnancy. Aims and Objective: To study the cases of thrombocyt…
View article: Impact of increase of caesarean section on postpartum hemorrhage in a tertiary care center of India over 6 years
Impact of increase of caesarean section on postpartum hemorrhage in a tertiary care center of India over 6 years Open
Background: PPH (postpartum hemorrhage) is the leading cause of maternal mortality. Despite of all the medical advancement, maternal mortality rates have declined greatly in the developed world, PPH remains a leading cause of maternal mort…
View article: To study the utilization pattern of various cervical cancer screening methods and their outcomes among patients visiting outpatient department of a tertiary care hospital
To study the utilization pattern of various cervical cancer screening methods and their outcomes among patients visiting outpatient department of a tertiary care hospital Open
Introduction: Cervical cancer is one of the leading causes of deaths among women worldwide, more so in developing countries like India. It is responsible for approximately 17% of deaths due to cancer in the 30-69 year age group. It is esti…
View article: Spectrum of prenatally diagnosed neural tube defects at a tertiary referral hospital in North India: a retrospective cohort study
Spectrum of prenatally diagnosed neural tube defects at a tertiary referral hospital in North India: a retrospective cohort study Open
Background: Neural tube defects, although largely preventable, constitute an important cause of neonatal mortality and morbidity. The study aimed to identify incidence rate, demographic profile, risk factors, and pregnancy outcomes of wome…
View article: Trends in postpartum Haemorrhage in a limited resource country: A review of 6 years in a tertiary care Centre of India
Trends in postpartum Haemorrhage in a limited resource country: A review of 6 years in a tertiary care Centre of India Open
Background: Postpartum haemorrhage (PPH) is the leading cause of maternal mortality. All women who carry a pregnancy beyond 20 weeks’ gestation are at risk for PPH and its sequelae. Although maternal mortality rates have declined greatly i…
View article: Socio-demographic characteristics and feto-maternal outcome in twin pregnancies at a tertiary care center: A 2 year study
Socio-demographic characteristics and feto-maternal outcome in twin pregnancies at a tertiary care center: A 2 year study Open
Background: Multiple gestation is considered a high-risk pregnancy. In India, 1% of the pregnancies are twin gestation and 10% of perinatal mortality can be attributed to twin pregnancies. Materials and Methods: This was a retrospective re…
View article: Laparoscopy: An emerging modality of management of ectopic pregnancy in a low resource setting
Laparoscopy: An emerging modality of management of ectopic pregnancy in a low resource setting Open
Aims and objectives: The main aim of the present study is to analyze the role of operative laparoscopy in ectopic pregnancy in a developing country, to study the clinical profile of patients and procedures done for ectopic pregnancy and to…
View article: A study of high-risk factors in ante-natal women at a tertiary care centre
A study of high-risk factors in ante-natal women at a tertiary care centre Open
Background: High-risk pregnancy refers to any condition in pregnancy that increases risk for morbidity or mortality in mother, fetus and neonate. Globally, nearly 5,29,000 women die due to pregnancy related complications. In India, 20-30% …
View article: Maternal mortality trends in “Tropical Country”
Maternal mortality trends in “Tropical Country” Open
Objective: To analyse the cause of maternal mortality at a tertiary health care centre. Methods: Cross sectional analytical study of maternal mortality from January 2017 to December 2018. Results: Over the study period total maternal death…
View article: Aberrant promoter methylation of <i>NOTCH1</i> and <i>NOTCH3</i> and its association with cervical cancer risk factors in North Indian population.
Aberrant promoter methylation of <i>NOTCH1</i> and <i>NOTCH3</i> and its association with cervical cancer risk factors in North Indian population. Open
Cervical cancer is the fourth most common type of cancer in women worldwide, and associated mortality is highest in developing countries like India. Limited studies are available on the role of NOTCH signaling pathway and promoter methylat…
View article: Safety and effectiveness of intravenous iron sucrose versus standard oral iron therapy in pregnant women with moderate-to-severe anaemia in India: a multicentre, open-label, phase 3, randomised, controlled trial
Safety and effectiveness of intravenous iron sucrose versus standard oral iron therapy in pregnant women with moderate-to-severe anaemia in India: a multicentre, open-label, phase 3, randomised, controlled trial Open
WHO, India.
View article: Caesarean scar pregnancy: a case report with review of management options
Caesarean scar pregnancy: a case report with review of management options Open
Cesarean scar pregnancy is a rare but life-threatening complication. It is the abnormal implantation of gestational sac into myometrium and fibrous scar of previous cesarean section. Its incidence is on rising trend due to increase in rate…
View article: Maternal and perinatal outcome in eclampsia at a tertiary care center
Maternal and perinatal outcome in eclampsia at a tertiary care center Open
Background: Preeclampsia is the occurrence of hypertension in combination with proteinuria, developing after 20 weeks gestation in a previously normotensive non-proteinuric patient. The objective of this study was to study the prevalance o…
View article: Role of Nonstress test in improving the perinatal outcome in pregnancies complicated by preeclampsia
Role of Nonstress test in improving the perinatal outcome in pregnancies complicated by preeclampsia Open
Introduction: Antepartum fetal surveillance is the assessment of fetal well being in utero before the onset of labour. It helps in early detection of fetuses at risk, so that timely management can prevent further deterioration, thereby red…
View article: Association of Luteinizing hormone and LH receptor gene polymorphism with susceptibility of Polycystic ovary syndrome
Association of Luteinizing hormone and LH receptor gene polymorphism with susceptibility of Polycystic ovary syndrome Open
Altered folliculogenesis and reproductive anomalies in polycystic ovary syndrome (PCOS) suggest that variations of genes involved in folliculogenesis might influence etiopathogenesis of this syndrome. The objective of this study was to ass…
View article: Study of pattern of nosocomial infections among post-operative patients following obstetrical and gynaecological surgeries in a tertiary care institute of northern India
Study of pattern of nosocomial infections among post-operative patients following obstetrical and gynaecological surgeries in a tertiary care institute of northern India Open
Background: Hospital acquired infections (HAIs) are the major causes of morbidity and mortality, functional disability and financial burden among the patients admitted in hospitals. The nosocomial infection has thrown a big challenge to th…
View article: Efficacy of 4×ED95 Loading Dose of Cisatracurium Besylate for Endotracheal Intubation – A Clinical Study
Efficacy of 4×ED95 Loading Dose of Cisatracurium Besylate for Endotracheal Intubation – A Clinical Study Open
Background: Cisatracurium besylate is the latest addition in the list of non-depolarizing neuromuscular blocking drugs. It has some very agreeable properties in terms of high potency with intermediate duration of action; but almost negligi…