Smruti Mokal
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View article: Long-term clinical outcomes of combined modality therapy for advanced-stage Hodgkin lymphoma in the PET era: A retrospective study
Long-term clinical outcomes of combined modality therapy for advanced-stage Hodgkin lymphoma in the PET era: A retrospective study Open
Background & objectives: The role of consolidation radiation therapy (CRT) after complete metabolic response to chemotherapy in advanced-stage (stage III and IV) Hodgkin lymphoma (HL) is controversial. This study was undertaken to assess t…
View article: A Questionnaire Survey of Current Practice in the Management of Internal Mammary Lymph Nodes in Breast Cancer
A Questionnaire Survey of Current Practice in the Management of Internal Mammary Lymph Nodes in Breast Cancer Open
Background Radiotherapy (RT) is an important modality in the management of breast cancers (BC). Large randomized trials have suggested that prophylactic regional nodal irradiation inclusive of internal mammary lymph nodes (IMLN) reduces BC…
View article: A Longitudinal Study to Reexamine the Mental Health Impact on Radiation Oncology Health Care Workers with the Launch of COVID-19 Vaccination Strategies in India
A Longitudinal Study to Reexamine the Mental Health Impact on Radiation Oncology Health Care Workers with the Launch of COVID-19 Vaccination Strategies in India Open
Introduction The novel coronavirus disease 2019 (COVID-19) catastrophe caused significant mental threats to health care workers (HCW), especially during the first wave of the pandemic. India successfully implemented vaccination strategies …
View article: Selecting lymph node–positive patients for adjuvant therapy after radical prostatectomy and extended pelvic lymphadenectomy: An outcome analysis of 100 node-positive patients managed without adjuvant therapy
Selecting lymph node–positive patients for adjuvant therapy after radical prostatectomy and extended pelvic lymphadenectomy: An outcome analysis of 100 node-positive patients managed without adjuvant therapy Open
Objective The aim of the study is to evaluate the effect of deferred androgen deprivation therapy on biochemical recurrence (BCR) and other survival parameters in node-positive prostate cancer patients after robot-assisted radical prostate…
View article: Short-course palliative hypofractionated radiotherapy in patients with poor-prognosis high-grade glioma: quality-of-life outcomes from a prospective phase II study
Short-course palliative hypofractionated radiotherapy in patients with poor-prognosis high-grade glioma: quality-of-life outcomes from a prospective phase II study Open
Purpose: To report longitudinal quality-of-life (QoL) outcomes in patients with poor prognosis high-grade glioma (HGG) treated with palliative hypofractionated radiotherapy (RT). Methods: Patients with poor-prognosis HGG based on age and p…
View article: Table of Contents (4 pgs)
Table of Contents (4 pgs) Open
View article: Translation and Validation of COST - FACIT (Version 2) Questionnaire into Hindi and Marathi to Assess Financial Toxicity in Indian Cancer Patients
Translation and Validation of COST - FACIT (Version 2) Questionnaire into Hindi and Marathi to Assess Financial Toxicity in Indian Cancer Patients Open
Background Cancer is one of the most expensive and exhaustive medical conditions with a huge impact on the financial condition of the patient and their family members. A lot of advancements have led to improvement in the survival of the pa…
View article: Deviation from standard cancer treatment during the first wave of the COVID-19 pandemic in India
Deviation from standard cancer treatment during the first wave of the COVID-19 pandemic in India Open
Background: During the coronavirus disease 2019 (COVID-19) pandemic, established best practices in cancer care were modified to diminish the risk of COVID-19 infection among patients and health-care workers. Objective: We aimed to study th…
View article: Demographics, Outcomes, Prognostic Factors in Adolescent-Adult Non-metastatic Ewing's Sarcomas- Experience from a Tertiary Cancer Center in India
Demographics, Outcomes, Prognostic Factors in Adolescent-Adult Non-metastatic Ewing's Sarcomas- Experience from a Tertiary Cancer Center in India Open
Background Outcome and toxicity data in adolescent-adult Ewing’s Sarcoma (AA-ES) patients is sparse and merits exploration. Methods Histopathologically confirmed, non-metastatic AA- ES patients, who received standard institutional combinat…
View article: Outcomes of Ewing sarcoma in adults over 40 years of age from a low-middle income country
Outcomes of Ewing sarcoma in adults over 40 years of age from a low-middle income country Open
Older adult ES patients benefit from aggressive multimodality treatment even in LMIC infrastructure. However, careful patient selection, close monitoring and pertinent dose modifications is imperative due to higher propensity for potential…
View article: Vascular endothelial growth factor as a potential prognosticator in Ewing Sarcoma: a tertiary care cancer center experience from India
Vascular endothelial growth factor as a potential prognosticator in Ewing Sarcoma: a tertiary care cancer center experience from India Open
Introduction: Vascular endothelial growth factor (VEGF)is an angiogenic marker and implicated in carcinogenesis and prognostication of cancers. However its prognostic potential in a rare cancer-Ewing’s sarcoma merits exploration. Methods: …
View article: The Epidemiological Trend of Esophageal Cancer in Mumbai, India, Over the Past Fifteen Years
The Epidemiological Trend of Esophageal Cancer in Mumbai, India, Over the Past Fifteen Years Open
Background: There has been a definite change in the histopathological spectrum of esophageal cancer towards adenocarcinoma seen in developed countries. In India such studies were limited. Materials and Methods: We retrospectively evaluated…
View article: Post-cricoid and Upper Oesophagus Cancers Treated with Organ Preservation Using Intensity-modulated Image-guided Radiotherapy: a Phase II Prospective Study of Outcomes, Toxicity and Quality of Life
Post-cricoid and Upper Oesophagus Cancers Treated with Organ Preservation Using Intensity-modulated Image-guided Radiotherapy: a Phase II Prospective Study of Outcomes, Toxicity and Quality of Life Open
Although the outcomes of PCUE cancers remain dismal, the use of state of the art diagnostic modalities, careful case selection and modern radiotherapy techniques improved outcomes as compared with before in this exclusive analysis of PCUE …
View article: Measuring Satisfaction in Breast Cancer Patients Receiving Ambulatory Care: A Validation Study
Measuring Satisfaction in Breast Cancer Patients Receiving Ambulatory Care: A Validation Study Open
Introduction Patient satisfaction constitutes a vital service quality indicator. It provides a measure of the gap in health-care requirements and patients' expectations. Objective The aim of this study was to perform linguistic validation …
View article: Management of Abdominal Ewing’s Sarcoma: A Single Institute Experience
Management of Abdominal Ewing’s Sarcoma: A Single Institute Experience Open
View article: Efficacy and safety of palbociclib and ribociclib in patients with estrogen and/or progesterone receptor positive, HER2 receptor negative metastatic breast cancer in routine clinical practice
Efficacy and safety of palbociclib and ribociclib in patients with estrogen and/or progesterone receptor positive, HER2 receptor negative metastatic breast cancer in routine clinical practice Open
Background There is scant data from India on efficacy and safety of palbociclib and ribociclib in routine clinical practice. Methods This retrospective, observational, single institution study included patients with estrogen and/or progest…
View article: Multinational Study to Assess Stress Levels Among the Health Care Workers of Radiation Oncology Community at the Outset of the COVID-19 Pandemic
Multinational Study to Assess Stress Levels Among the Health Care Workers of Radiation Oncology Community at the Outset of the COVID-19 Pandemic Open
PURPOSE To evaluate stress levels among the health care workers (HCWs) of the radiation oncology community in Asian countries. METHODS HCWs of the radiation oncology departments from 29 tertiary cancer care centers of Bangladesh, India, In…
View article: Can We Avoid Axillary Lymph Node Dissection (ALND) in Patients with 1–2 Positive Sentinel/Low Axillary Lymph Nodes (SLN/LAS+) in the Indian Setting?
Can We Avoid Axillary Lymph Node Dissection (ALND) in Patients with 1–2 Positive Sentinel/Low Axillary Lymph Nodes (SLN/LAS+) in the Indian Setting? Open
View article: Outcomes and prognostic factors in adolescents and young adults with ALL treated with a modified BFM-90 protocol
Outcomes and prognostic factors in adolescents and young adults with ALL treated with a modified BFM-90 protocol Open
The use of pediatrics-inspired protocols in adolescent and young adult (AYA) acute lymphoblastic leukemia (ALL) results in superior survival compared with the adult protocols. Pediatrics-inspired protocols carry an increased risk of toxici…
View article: Pregnancy associated breast cancer (PABC): Report from a gestational cancer registry from a tertiary cancer care centre, India
Pregnancy associated breast cancer (PABC): Report from a gestational cancer registry from a tertiary cancer care centre, India Open
Data from the first Indian PABC registry showed that the majority had delayed diagnosis and aggressive features(TNBC, higher grade). Treatment was feasible in majority and stage matched outcomes were comparable to non-PABCs.
View article: Adolescent-Adult Non-metastatic Ewing Sarcoma- Experience from a large developing country
Adolescent-Adult Non-metastatic Ewing Sarcoma- Experience from a large developing country Open
Background Outcomes of Ewing sarcoma (ES) in low and middle income countries lags behind the rest of the world owing to multiple tumoral, logistical and socio-economic factors. The data of outcomes and toxicity in these countries is sparse…
View article: Does Operable Stage IV Gingivobuccal Cancers Need Further Prognostic Subgrouping?
Does Operable Stage IV Gingivobuccal Cancers Need Further Prognostic Subgrouping? Open
View article: The role of chemotherapy in patients with small cell lung cancer and poor performance status
The role of chemotherapy in patients with small cell lung cancer and poor performance status Open
Chemotherapy prolongs survival in patients with SCLC and poor PS. Administering an initial attenuated chemotherapy regimen followed by standard full-dose chemotherapy when the PS improves may lower toxicity and improve tolerance.
View article: The role of chemotherapy in patients with small cell lung cancer and poor performance status
The role of chemotherapy in patients with small cell lung cancer and poor performance status Open
There are limited data on the role of chemotherapy in patients with small cell lung cancer (SCLC) and poor performance status (PS). This was a retrospective analysis of a prospective observational study in patients with SCLC and PS 3 or 4.…
View article: A randomized trial of stereotactic versus conventional radiotherapy in young patients with low-grade brain tumors: occupational therapy-based neurocognitive data
A randomized trial of stereotactic versus conventional radiotherapy in young patients with low-grade brain tumors: occupational therapy-based neurocognitive data Open
Background Radiotherapy for brain tumors in young patients is not only associated with improved survival but also long-term neurocognitive sequelae. We aimed to compare group differences in the executive neurocognitive outcomes in young pa…