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View article: Unraveling mutagenic processes influencing the tumor mutational patterns of individuals with constitutional mismatch repair deficiency
Unraveling mutagenic processes influencing the tumor mutational patterns of individuals with constitutional mismatch repair deficiency Open
View article: Exome-based cancer predisposition gene testing can provide a genetic diagnosis for individuals with heterogeneous tumor phenotypes
Exome-based cancer predisposition gene testing can provide a genetic diagnosis for individuals with heterogeneous tumor phenotypes Open
The development of multiple primary tumors is one of the hallmarks of hereditary cancer. The phenotypic presentation of individuals with multiple primary tumors is often heterogeneous, which hampers the establishment of a genetic diagnosis…
View article: The genomic landscape of breast and non-breast cancers from individuals with germline CHEK2 deficiency
The genomic landscape of breast and non-breast cancers from individuals with germline CHEK2 deficiency Open
CHEK2 is considered to be involved in homologous recombination repair (HRR). Individuals who have germline pathogenic variants (gPVs) in CHEK2 are at increased risk to develop breast cancer and likely other primary cancers. PARP inhibitors…
View article: The heterogeneous cancer phenotype of individuals with biallelic germline pathogenic variants in CHEK2
The heterogeneous cancer phenotype of individuals with biallelic germline pathogenic variants in CHEK2 Open
View article: Plant Products for Musculoskeletal, Respiratory, Circulatory, and Genitourinary Disorders in Eastern and South-Eastern Serbia – Folk Uses Comparison with Official Recommendations
Plant Products for Musculoskeletal, Respiratory, Circulatory, and Genitourinary Disorders in Eastern and South-Eastern Serbia – Folk Uses Comparison with Official Recommendations Open
Eastern and south-eastern Serbia is a cultural crossroads between East and West, and due to its economic underdevelopment, the traditional use of medicinal plants remains crucial in healthcare even today.This study aimed to collect and pre…
View article: Gene Expression and DNA Methylation in Human Papillomavirus Positive and Negative Head and Neck Squamous Cell Carcinomas
Gene Expression and DNA Methylation in Human Papillomavirus Positive and Negative Head and Neck Squamous Cell Carcinomas Open
High-risk human papillomaviruses (HPV) are important agents, responsible for a large percentage of the 745,000 cases of head and neck squamous cell carcinomas (HNSCC), which were identified worldwide in 2020. In addition to being virally i…