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View article: Magnesium supplementation improves ovarian folliculogenesis in type 1 diabetes mellitus
Magnesium supplementation improves ovarian folliculogenesis in type 1 diabetes mellitus Open
Introduction : Type 1 diabetes mellitus (T1DM) is associated with oxidative stress and metabolic dysfunction, contributing to impaired ovarian folliculogenesis and reproductive dysfunction. Meanwhile, magnesium plays a crucial role in impr…
View article: Therapeutic Potential of Muli Banana Peel Extract on Modulating Inflammation, Proliferation, and Apoptosis in A Rat Model of Endometriosis
Therapeutic Potential of Muli Banana Peel Extract on Modulating Inflammation, Proliferation, and Apoptosis in A Rat Model of Endometriosis Open
Endometriosis is a condition characterized by the growth of tissue resembling the endometrium outside the uterine cavity, which can lead to inflammation, pelvic pain, and infertility. Muli Banana Peel Extract (MBPE) derived from Musa acumi…
View article: Bibliometric mapping of secretomes, exosomes, and extracellular vesicles in Alzheimer’s disease
Bibliometric mapping of secretomes, exosomes, and extracellular vesicles in Alzheimer’s disease Open
Context: Alzheimer’s Disease (AD) is a neurodegenerative disorder with limited treatment options, primarily addressing symptoms without targeting underlying mechanisms. Emerging therapies involving secretomes, exosomes, and extracellular v…
View article: Effects of aerobic exercise and high-intensity interval training on muscle damage in an overtraining rat model
Effects of aerobic exercise and high-intensity interval training on muscle damage in an overtraining rat model Open
Background: Overtraining is commonly associated with elevated oxidative stress, inflammatory responses, and structural damage to muscle fibers, all of which contribute to a decline in physical performance. This study aimed to assess the im…
View article: The Effect of Moringa Oleifera Ethanol Extract on Improving Cisplatin Induced Liver Cells Damages
The Effect of Moringa Oleifera Ethanol Extract on Improving Cisplatin Induced Liver Cells Damages Open
M. oleifera exhibits a dose-dependent ability to mitigate inflammation, oxidative stress, and liver cell damage caused by cisplatin. The pre-treatment regimen with M. oleifera was the most effective.
View article: Biocultural Expectancy of Breastfeeding Practice: A Qualitative Content Analysis Using Bibliometric Review
Biocultural Expectancy of Breastfeeding Practice: A Qualitative Content Analysis Using Bibliometric Review Open
This research explores the philosophy of breastfeeding practice as a glory. The research objectives are to discover (explore) the deepest structure of breastfeeding practices, explain (explain) the structures found in the context of genera…
View article: Modulation of Oxidative Stress Markers and Inflammatory Mediators in Alveolar Damage Induced by Anaerobic Exercise
Modulation of Oxidative Stress Markers and Inflammatory Mediators in Alveolar Damage Induced by Anaerobic Exercise Open
Anaerobic exercise, characterized by high-intensity, short-duration physical activity, induces a unique physiological response that includes oxidative stress and inflammation. This study investigates the modulation of oxidative stress mark…
View article: Association between vaspin rs2236242 gene polymorphism and atherosclerosis in ischemic stroke patients with diabetes mellitus in the Indonesian population
Association between vaspin rs2236242 gene polymorphism and atherosclerosis in ischemic stroke patients with diabetes mellitus in the Indonesian population Open
BACKGROUND Stroke is the third leading cause of morbidity and second in mortality worldwide. Diabetes mellitus (DM) is a risk factor for stroke. Vaspin and single nucleotide polymorphism (SNP) rs2236242 involved DM pathogenesis. This study…
View article: Utilizing secretomes as a novel molecular-based therapy for Parkinson’s disease: A scoping review
Utilizing secretomes as a novel molecular-based therapy for Parkinson’s disease: A scoping review Open
Parkinson’s disease (PD) is a neurodegenerative disorder that affects multiple body systems and results in a variety of motor and non-motor symptoms. Recent research has highlighted the importance of secretome, a diverse array of bioactive…
View article: The impact of environmental factors on the immunopathogenesis of osteoporosis: A systematic review
The impact of environmental factors on the immunopathogenesis of osteoporosis: A systematic review Open
Osteoporosis is a metabolic bone disease predominantly driven by environmental variables that damage bone microarchitecture and increase the risk of fractures. This systematic study analyzes environmental variables' impact on osteoporosis …
View article: <b>Effects of <i>Moringa oleifera</i> leaves on CRP, MDA, and alevels in a mouse model of preeclampsia</b>
<b>Effects of <i>Moringa oleifera</i> leaves on CRP, MDA, and alevels in a mouse model of preeclampsia</b> Open
Background: Preeclampsia is a serious pregnancy complication characterized by high blood pressure and organ dysfunction, primarily affecting the placenta and kidneys. Reduced placental blood flow can have severe consequences for both the m…
View article: Association between air pollution and osteoporosis: A systematic review
Association between air pollution and osteoporosis: A systematic review Open
Background: Osteoporosis is a major worldwide health problem associated with lower bone mineral density (BMD) and higher fracture risk, which contributes to increased morbidity and healthcare costs. Meanwhile, some modifiable environmental…
View article: Effect of Phenol and Saponin on Apis Dorsata Forest Honey and docking molecule on preeclamptic markers
Effect of Phenol and Saponin on Apis Dorsata Forest Honey and docking molecule on preeclamptic markers Open
Molecular docking is an important computational method for drug design. It can be used to predict receptor binding interactions with ligans. In addition, phenol-derived compounds and Saponins are also reported to have various activities su…
View article: Effect of Ethanol Extract of Okra Fruit on NF-ΚB Expression in Wound Healing Wistar Rats With Diabetes Mellitus
Effect of Ethanol Extract of Okra Fruit on NF-ΚB Expression in Wound Healing Wistar Rats With Diabetes Mellitus Open
Objectives:The main objective of the study was to see the effect of Okra Fruit Ethanol Extract on NF-κB Expression in the Healing of Wistar Rat Wounds in the Diabetes Mellitus Model. Theoretical Framework: NF-κB is a critical component in …
View article: Investigating the Influence of 0.75% Ethanol Extract Gel from “Kaempferia galanga L Rhizoma” on Mild and Moderate Acne Vulgaris Among High School Students
Investigating the Influence of 0.75% Ethanol Extract Gel from “Kaempferia galanga L Rhizoma” on Mild and Moderate Acne Vulgaris Among High School Students Open
Background: Acne vulgaris is a prevalent dermatological condition characterized by the inflammation of sebaceous follicles. This inflammation results in various clinical manifestations, including open and closed comedones, papules, pustule…
View article: Mesenchymal stem cell secretome decreases inflammation in sepsis model
Mesenchymal stem cell secretome decreases inflammation in sepsis model Open
Aims: To determine the impact of MSC secretome on the nuclear factor-kappa B (NF-kB) expression in the liver. Methods: This research is a posttest-only control design group experimental study. This experiment used 40 mice. There were eight…
View article: Effect of erythropoietin on cerebral palsy prevention in hypoxic-ischemic encephalopathy. Hemoglobin, C-reactive protein, caspase-3, and tumor necrosing factor-α levels
Effect of erythropoietin on cerebral palsy prevention in hypoxic-ischemic encephalopathy. Hemoglobin, C-reactive protein, caspase-3, and tumor necrosing factor-α levels Open
Context: Hypoxic ischemic encephalopathy (HIE) is one of the leading causes of cerebral palsy (CP) and neonatal mortality in developing countries. Erythropoietin (Epo) is one of the newest neuroprotective therapies to prevent cerebral pals…
View article: The effectiveness of psychocurative on the anxiety scale and the levels of cortisol, serotonin, and prolactin in postpartum women
The effectiveness of psychocurative on the anxiety scale and the levels of cortisol, serotonin, and prolactin in postpartum women Open
Context: The anxiety experienced by mothers during postpartum may have a negative impact on the emotional, psychological, and social development of newborns. Moreover, a psychological intervention known as psychocurative aims to maintain a…
View article: Bibliometric analysis of research in Moringa oleifera Lam. and atherosclerosis
Bibliometric analysis of research in Moringa oleifera Lam. and atherosclerosis Open
Context: Moringa oleifera is a plant with many benefits, and its polyphenols have potential in the medication system due to their hypoglycemic activity. One of its functions is to prevent atherosclerosis by inhibiting the production of ROS…
View article: A bibliometric analysis of 10 years of publications on L-citrulline
A bibliometric analysis of 10 years of publications on L-citrulline Open
Context: L-citrulline is a non-essential amino acid primarily sourced from watermelon (Citrullus vulgaris). Many studies on L-citrulline have been conducted in the past 10 years. However, no bibliometric analyses have been performed. Aims:…
View article: Effects of wet cupping in a rat model of primary dysmenorrhea
Effects of wet cupping in a rat model of primary dysmenorrhea Open
These results indicate that WC is more effective than DC in suppressing dysmenorrhea symptoms, modulating the hormone level ratio, and repairing uterine pathology. The potential benefits of cupping provide an opportunity for further studie…
View article: The Effect of Ginkgo Biloba Extract on Oxidative Stress, Anti-Inflammatory and Antiapoptotic in Vitiligo Treated with Topical Desoxymethasone
The Effect of Ginkgo Biloba Extract on Oxidative Stress, Anti-Inflammatory and Antiapoptotic in Vitiligo Treated with Topical Desoxymethasone Open
Vitiligo is a progressive and multifactorial condition of skin, mucosa, and hair depigmentation. Loss of functional melanocytes leads to the appearance of white macules on the skin, often affecting the lips and genitalia. The impact extend…
View article: Aerobic exercise improves spatial memory in a rat model of meningitis
Aerobic exercise improves spatial memory in a rat model of meningitis Open
Infections of the nervous system, such as acute bacterial meningitis, pose serious health problems that require immediate intervention. In experimental animals, exposure to lipopolysaccharide (LPS) is used to induce meningitis. Aside from …
View article: Exploring the anti-inflammatory effects of Nigella sativa on cyclooxygenase-2 through the nuclear factor-kappa B pathway in an Aspergillus niger-induced otitis externa mouse model
Exploring the anti-inflammatory effects of Nigella sativa on cyclooxygenase-2 through the nuclear factor-kappa B pathway in an Aspergillus niger-induced otitis externa mouse model Open
Inflammatory condition of the external ear canal is called otitis externa (OE). This condition is often associated with microbial infections such as Aspergillus niger . This research aims to assess the anti-inflammatory activities of the N…
View article: A molecular docking insight: Phyllanthus niruri L. constituents targeting MMP-9 for angiogenesis inhibition and IL-1beta for antiinflammatory action in endometriosis therapy
A molecular docking insight: Phyllanthus niruri L. constituents targeting MMP-9 for angiogenesis inhibition and IL-1beta for antiinflammatory action in endometriosis therapy Open
Endometriosis, characterized by inflammatory lesions resembling endometrium outside the uterine cavity, induces chronic inflammation, anatomical changes and persistent pain. The expression of Interleukin 1beta (IL-1beta) is significantly a…
View article: Therapeutic Efficacy of Wet Cupping on Uterine Inflammation in Primary Dysmenorrhea: An In Vivo Investigation Targeting Bilateral L4/L5 Vertebrae
Therapeutic Efficacy of Wet Cupping on Uterine Inflammation in Primary Dysmenorrhea: An In Vivo Investigation Targeting Bilateral L4/L5 Vertebrae Open
Primary dysmenorrhea (PD) is a prevalent problem in gynecology affecting the quality of life for young women. This medical condition is often responsible for the absence of young women from school or work, increasing the risk of developing…
View article: Impacts of Phyllanthus niruri extract on biomarker levels, macrophage count, and lesion area in an endometriotic rat model
Impacts of Phyllanthus niruri extract on biomarker levels, macrophage count, and lesion area in an endometriotic rat model Open
Endometriosis is a gynecological disorder characterized by chronic inflammation, anatomical changes, prolonged pain, and infertility. On the other hand, Phyllanthus niruri is recognized for its pharmacological effects, which might be benef…
View article: Cisplatin-Induced Oral Mucositis Prevention: Nigella sativa’s Anti-Inflammatory Role through NFκB Pathway
Cisplatin-Induced Oral Mucositis Prevention: Nigella sativa’s Anti-Inflammatory Role through NFκB Pathway Open
Prevention of Cisplatin-induced oral mucositis (OM) Presents substantial challenges due to its association with oxidative stress, inflammation, apoptosis and NFκB pathway activation. This study aims to evaluate the potential of Nigella sat…
View article: Postnatal Complementary Care Training Model for Preeclampsy
Postnatal Complementary Care Training Model for Preeclampsy Open
The highest cause of maternal death in Banyumas Regency, Indonesia in 2022 is preeclampsia during the postpartum period (66.7 percent). However, preeclampsia detection is only carried out if there are symptoms or complaints. Complementary …
View article: Revealing the Therapeutic Potential of Nigella Sativa Extract in Aspergillus Niger-Induced Otitis Externa: Anti-Inflammatory and Antioxidant Properties
Revealing the Therapeutic Potential of Nigella Sativa Extract in Aspergillus Niger-Induced Otitis Externa: Anti-Inflammatory and Antioxidant Properties Open
Otitis externa (OE), a fungal infection of the external auditory canal, often involving Aspergillus niger, can lead to OE externa, posing severe health risks. Establishing an animal model of OE induced by Aspergillus niger, this study aime…