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View article: Diving into the metabolic interactions of titanium dioxide nanoparticles in “Sparus aurata” and “Ruditapes philippinarum”
Diving into the metabolic interactions of titanium dioxide nanoparticles in “Sparus aurata” and “Ruditapes philippinarum” Open
The biological response to nanomaterials exposure depends on their properties, route of exposure, or model organism. Titanium dioxide nanoparticles (TiO2 NPs) are among the most used nanomaterials; however, concerns related to oxidative st…
View article: Characterization of NR1J1 Paralog Responses of Marine Mussels: Insights from Toxins and Natural Activators
Characterization of NR1J1 Paralog Responses of Marine Mussels: Insights from Toxins and Natural Activators Open
The pregnane X receptor (PXR) is a nuclear hormone receptor that plays a pivotal role in regulating gene expression in response to various ligands, particularly xenobiotics. In this context, the aim of this study was to shed light on the l…
View article: The transcriptome assembly of the European freshwater mussel Unio elongatulus C. Pfeiffer, 1825
The transcriptome assembly of the European freshwater mussel Unio elongatulus C. Pfeiffer, 1825 Open
Freshwater mussels of the order Unionida are a global conservation concern. Species of this group are strictly freshwater, sessile, slow-growing animals and, extremely sensitive to environmental changes. Human-mediated changes in freshwate…
View article: First characterization of the nuclear receptor superfamily in the Mediterranean mussel <i>Mytilus galloprovincialis</i> : developmental expression dynamics and potential susceptibility to environmental chemicals
First characterization of the nuclear receptor superfamily in the Mediterranean mussel <i>Mytilus galloprovincialis</i> : developmental expression dynamics and potential susceptibility to environmental chemicals Open
Endocrine-disrupting chemicals (EDCs) represent a global threat to human health and the environment. In vertebrates, lipophilic EDCs primarily act by mimicking endogenous hormones, thus interfering with the transcriptional activity of nucl…
View article: Supplementary File 2 from First characterization of the nuclear receptor superfamily in the Mediterranean mussel <i>Mytilus galloprovincialis</i>: developmental expression dynamics and potential susceptibility to environmental chemicals
Supplementary File 2 from First characterization of the nuclear receptor superfamily in the Mediterranean mussel <i>Mytilus galloprovincialis</i>: developmental expression dynamics and potential susceptibility to environmental chemicals Open
Supplementary Table 1: Protein domains of nuclear receptor (NR) proteins identified in the Mytilus galloprovincialis genome. Supplementary Table 2: Accession numbers and annotation of nuclear receptors (NRs) used for phylogenetic analyses …
View article: Getting fat and stressed: Effects of dietary intake of titanium dioxide nanoparticles in the liver of turbot Scophthalmus maximus
Getting fat and stressed: Effects of dietary intake of titanium dioxide nanoparticles in the liver of turbot Scophthalmus maximus Open
The extensive use of nanomaterials, including titanium dioxide nanoparticles (TiO2 NPs), raises concerns about their persistence in ecosystems. Protecting aquatic ecosystems and ensuring healthy and safe aquaculture products requires the a…
View article: The transcriptome assembly of the European freshwater mussel Unio elongatulus C. Pfeiffer, 1825
The transcriptome assembly of the European freshwater mussel Unio elongatulus C. Pfeiffer, 1825 Open
Freshwater mussels of the order Unionida are a global conservation concern. Species of this group are strictly freshwater, sessile, and slow-growing animals, extremely sensitive to environmental changes. Human-mediated changes in freshwate…
View article: Proteomics reveals multiple effects of titanium dioxide and silver nanoparticles in the metabolism of turbot, Scophthalmus maximus
Proteomics reveals multiple effects of titanium dioxide and silver nanoparticles in the metabolism of turbot, Scophthalmus maximus Open
Titanium dioxide (TiO2) and silver (Ag) NPs are among the most used engineered inorganic nanoparticles (NPs); however, their potential effects to marine demersal fish species, are not fully understood. Therefore, this study aimed to assess…
View article: Proteomics reveals multiple effects of titanium dioxide and silver nanoparticles in the metabolism of turbot, Scophthalmus maximus
Proteomics reveals multiple effects of titanium dioxide and silver nanoparticles in the metabolism of turbot, Scophthalmus maximus Open
Titanium dioxide (TiO2) and silver (Ag) NPs are among the most used engineered inorganic nanoparticles (NPs); however, their potential effects to marine demersal fish species, are not fully understood. Therefore, this study aimed to assess…
View article: Proteomics reveals multiple effects of titanium dioxide and silver nanoparticles in the metabolism of turbot, Scophthalmus maximus
Proteomics reveals multiple effects of titanium dioxide and silver nanoparticles in the metabolism of turbot, Scophthalmus maximus Open
Titanium dioxide (TiO2) and silver (Ag) NPs are among the most used engineered inorganic nanoparticles (NPs); however, their potential effects to marine demersal fish species, are not fully understood. Therefore, this study aimed to assess…
View article: The Preservation of PPARγ Genome Duplicates in Some Teleost Lineages: Insights into Lipid Metabolism and Xenobiotic Exploitation
The Preservation of PPARγ Genome Duplicates in Some Teleost Lineages: Insights into Lipid Metabolism and Xenobiotic Exploitation Open
Three peroxisome proliferator-activated receptor paralogues (PPARα, -β and -γ) are currently recognized in vertebrate genomes. PPARγ is known to modulate nutrition, adipogenesis and immunity in vertebrates. Natural ligands of PPARγ have be…
View article: Comparison of Sample Preparation Methods for Shotgun Proteomic Studies in Aquaculture Species
Comparison of Sample Preparation Methods for Shotgun Proteomic Studies in Aquaculture Species Open
Proteomics has been recently introduced in aquaculture research, and more methodological studies are needed to improve the quality of proteomics studies. Therefore, this work aims to compare three sample preparation methods for shotgun LC–…
View article: Of Retinoids and Organotins: The Evolution of the Retinoid X Receptor in Metazoa
Of Retinoids and Organotins: The Evolution of the Retinoid X Receptor in Metazoa Open
Nuclear receptors (NRs) are transcription factors accomplishing a multiplicity of functions, essential for organismal homeostasis. Among their numerous members, the retinoid X receptor (RXR) is a central player of the endocrine system, wit…
View article: An Orthologue of the Retinoic Acid Receptor (RAR) Is Present in the Ecdysozoa Phylum Priapulida
An Orthologue of the Retinoic Acid Receptor (RAR) Is Present in the Ecdysozoa Phylum Priapulida Open
Signalling molecules and their cognate receptors are central components of the Metazoa endocrine system. Defining their presence or absence in extant animal lineages is critical to accurately devise evolutionary patterns, physiological shi…
View article: Liver transcriptome resources of four commercially exploited teleost species
Liver transcriptome resources of four commercially exploited teleost species Open
The generation of omic resources is central to develop adequate management strategies for species with economic value. Here, we provide high-coverage RNA-seq datasets of liver tissue (containing between 80,2 and 88,4 million of paired-end …
View article: Evolutionary Plasticity in Detoxification Gene Modules: The Preservation and Loss of the Pregnane X Receptor in Chondrichthyes Lineages
Evolutionary Plasticity in Detoxification Gene Modules: The Preservation and Loss of the Pregnane X Receptor in Chondrichthyes Lineages Open
To appraise how evolutionary processes, such as gene duplication and loss, influence an organism’s xenobiotic sensitivity is a critical question in toxicology. Of particular importance are gene families involved in the mediation of detoxif…
View article: “Out of the Can”: A Draft Genome Assembly, Liver Transcriptome, and Nutrigenomics of the European Sardine, Sardina pilchardus
“Out of the Can”: A Draft Genome Assembly, Liver Transcriptome, and Nutrigenomics of the European Sardine, Sardina pilchardus Open
Clupeiformes, such as sardines and herrings, represent an important share of worldwide fisheries. Among those, the European sardine (Sardina pilchardus, Walbaum 1792) exhibits significant commercial relevance. While the last decade showed …
View article: &ldquo;Out of the Can&rdquo;: A Draft Genome Assembly, Liver Transcriptome and Nutrigenomics of the European Sardine, <em>Sardina p</em><em>ilchardus</em>
“Out of the Can”: A Draft Genome Assembly, Liver Transcriptome and Nutrigenomics of the European Sardine, <em>Sardina p</em><em>ilchardus</em> Open
Clupeiformes, such as sardines and herrings, represent an important share of worldwide fisheries. Among those, the European sardine (Sardina pilchardus, Walbaum 1792) exhibits significant commercial relevance. While the last decade showed …
View article: “Out of the can”: a draft genome assembly, liver transcriptome and nutrigenomics of the European sardine, Sardina pilchardus
“Out of the can”: a draft genome assembly, liver transcriptome and nutrigenomics of the European sardine, Sardina pilchardus Open
Clupeiformes, such as sardines and herrings, represent an important share of worldwide fisheries. Among those, the European sardine (Sardina pilchardus, Walbaum 1792) exhibits significant commercial relevance. While the last decade showed …
View article: Expansion, retention and loss in the Acyl-CoA Synthetase<i>“Bubblegum”</i>(<i>Acsbg</i>) gene family in vertebrate history
Expansion, retention and loss in the Acyl-CoA Synthetase<i>“Bubblegum”</i>(<i>Acsbg</i>) gene family in vertebrate history Open
A bstract Fatty acids (FAs) constitute a considerable fraction of all lipid molecules with a fundamental role in numerous physiological processes. In animals, the majority of complex lipid molecules are derived from the transformation of F…
View article: A resource for sustainable management: De novo assembly and annotation of the liver transcriptome of the Atlantic chub mackerel, Scomber colias
A resource for sustainable management: De novo assembly and annotation of the liver transcriptome of the Atlantic chub mackerel, Scomber colias Open
Mackerels represent a valuable fishery worldwide. Their ample geographic distribution and capture levels make them an insightful model to address stock management strategies in the context of global changes. Yet, and despite recent impress…
View article: LXRα and LXRβ nuclear receptors evolved in the common ancestor of gnathostomes
LXRα and LXRβ nuclear receptors evolved in the common ancestor of gnathostomes Open
Nuclear receptors (NRs) regulate numerous aspects of the endocrine system. They mediate endogenous and exogenous cues, ensuring a homeostatic control of development and metabolism. Gene duplication, loss and mutation have shaped the repert…