Sofia L. Pedersen
YOU?
Author Swipe
View article: The hepcidin‐ferroportin axis influences mitochondrial function, proliferation, and migration in pulmonary artery endothelial and smooth muscle cells
The hepcidin‐ferroportin axis influences mitochondrial function, proliferation, and migration in pulmonary artery endothelial and smooth muscle cells Open
Elevated circulating hepcidin levels have been reported in patients with pulmonary artery hypertension (PAH). Hepcidin has been shown to promote proliferation of human pulmonary artery smooth muscle cells (PASMCs) in vitro, suggesting a po…
View article: Non-canonical induction of autophagy increases adeno-associated virus type 2 (AAV2) transduction efficiency
Non-canonical induction of autophagy increases adeno-associated virus type 2 (AAV2) transduction efficiency Open
Adeno-associated virus (AAV) serotypes infect a wide range of cell types, making this member of the parvovirus family a versatile tool in gene therapy. Infection as well as transduction is set in motion by means of specific receptors in co…
View article: The hepcidin-ferroportin axis influences mitochondrial function, proliferation, and migration in pulmonary artery endothelial and smooth muscle cells
The hepcidin-ferroportin axis influences mitochondrial function, proliferation, and migration in pulmonary artery endothelial and smooth muscle cells Open
Rationale Elevated circulating hepcidin levels have been reported in patients with pulmonary artery hypertension (PAH). Hepcidin has been shown to promote proliferation of human pulmonary artery smooth muscle cells (PASMCs) in vitro, sugge…
View article: Identification and characterization of stem-bulge RNAs in <i>Drosophila melanogaster</i>
Identification and characterization of stem-bulge RNAs in <i>Drosophila melanogaster</i> Open
Non-coding Y RNAs and stem-bulge RNAs are homologous small RNAs in vertebrates and nematodes, respectively. They share a conserved function in the replication of chromosomal DNA in these two groups of organisms. However, functional homolog…
View article: Identification and characterization of stem-bulge RNAs in <i>Drosophila melanogaster</i>
Identification and characterization of stem-bulge RNAs in <i>Drosophila melanogaster</i> Open
Non-coding Y RNAs and stem-bulge RNAs are homologous small RNAs in vertebrates and nematodes, respectively. They share a conserved function in the replication of chromosomal DNA in these two groups of organisms. However, functional homolog…
View article: Pulmonary Arterial Hypertension: Iron Matters
Pulmonary Arterial Hypertension: Iron Matters Open
The interplay between iron and oxygen is longstanding and central to all aerobic life. Tight regulation of these interactions including homeostatic regulation of iron utilization ensures safe usage of this limited resource. However, when c…