Susana Molina
YOU?
Author Swipe
Sweet Taste Receptors’ Genetic Variability in Advanced Potential Targets of Obesity Open
Background: Obesity, mainly visceral obesity, causes a low-grade of chronic inflammation (meta-inflammation), associated with comorbidities such as type 2 diabetes, cardiovascular diseases, and certain cancers. Precision Nutrition aims to …
View article: Behavioral variant frontotemporal neurocognitive disorder or psychiatric disorder: a diagnostic challenge
Behavioral variant frontotemporal neurocognitive disorder or psychiatric disorder: a diagnostic challenge Open
Introduction The behavioral variant of frontotemporal neurocognitive disorder is the most common clinical syndrome within frontotemporal neurocognitive disorders and is primarily characterized by progressive changes in personality and beha…
An untargeted metabolomic analysis of acute AFB1 treatment in liver, breast, and lung cells Open
Aflatoxin B1 (AFB1) is a class 1 carcinogen and mycotoxin known to contribute to the development of hepatocellular carcinoma (HCC), growth impairment, altered immune system modulation, and malnutrition. AFB1 is synthesized by Aspergillus f…
View article: Randomized clinical trial in cancer patients shows immune metabolic effects exerted by formulated bioactive phenolic diterpenes with potential clinical benefits
Randomized clinical trial in cancer patients shows immune metabolic effects exerted by formulated bioactive phenolic diterpenes with potential clinical benefits Open
Background Nutrients, including bioactive natural compounds, have been demonstrated to affect key metabolic processes implicated in tumor growth and progression, both in preclinical and clinical trials. Although the application of precisio…
View article: Effect of fiber-modified kombucha tea on gut microbiota in healthy population: A randomized controlled trial (RCT)
Effect of fiber-modified kombucha tea on gut microbiota in healthy population: A randomized controlled trial (RCT) Open
The studied fiber-enriched kombucha drink demonstrated potential health benefits, including triglyceride modulation and positive alterations in gut microbiota composition. These findings suggest its promise as a functional beverage for imp…
AI4FoodDB: a database for personalized e-Health nutrition and lifestyle through wearable devices and artificial intelligence Open
The increasing prevalence of diet-related diseases calls for an improvement in nutritional advice. Personalized nutrition aims to solve this problem by adapting dietary and lifestyle guidelines to the unique circumstances of each individua…
Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3′ untranslated region Open
Background Overweight and obesity are defined by an anomalous or excessive fat accumulation that may compromise health. To find single-nucleotide polymorphisms (SNPs) influencing metabolic phenotypes associated with the obesity state, we a…
“GENYAL” Study to Childhood Obesity Prevention: Methodology and Preliminary Results Open
Objective This article describes the methodology and summarizes some preliminary results of the GENYAL study aiming to design and validate a predictive model, considering both environmental and genetic factors, that identifies children who…
View article: Additional file 2 of Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3′ untranslated region
Additional file 2 of Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3′ untranslated region Open
Additional file 2: Table S1. Phenotypic characteristics of healthy volunteers (Full set and population subsets). Table S2. List of SNPs, genes, location, type, and minor allele frequencies genotyped in this study. Table S3. Detailed inform…
Polymorphic Appetite Effects on Waist Circumference Depend on rs3749474 CLOCK Gene Variant Open
Chronobiological aspects controlled by CLOCK genes may influence obesity incidence. Although there are studies that show an association between the expression of these genes and energy intake, waist circumference or abdominal obesity pheno…
Tolerability and Safety of a Nutritional Supplement with Potential as Adjuvant in Colorectal Cancer Therapy: A Randomized Trial in Healthy Volunteers Open
Bioactive supplements display relevant therapeutic properties when properly applied according to validated molecular effects. Our previous research efforts established the basis to develop a dietary supplement based on a Rosmarinus officin…
GCKR rs780094 Polymorphism as A Genetic Variant Involved in Physical Exercise Open
Exercise performance is influenced by genetics. However, there is a lack of knowledge about the role played by genetic variability in the frequency of physical exercise practice. The objective was to identify genetic variants that modulate…
Metabolomic profiling of human lung tumor tissues – nucleotide metabolism as a candidate for therapeutic interventions and biomarkers Open
Although metabolomics has attracted considerable attention in the field of lung cancer (LC) detection and management, only a very limited number of works have applied it to tissues. As such, the aim of this study was the thorough analysis …
Targeting the lipid metabolic axis ACSL/SCD in colorectal cancer progression by therapeutic miRNAs: miR-19b-1 role Open
An abnormal acyl-CoA synthetase/stearoyl-CoA desaturase (ACSL/SCD) lipid network fuels colon cancer progression, endowing cells with invasive and migratory properties. Therapies against this metabolic network may be useful to improve clini…
Micro<span>RNA</span>‐661 modulates redox and metabolic homeostasis in colon cancer Open
Cancer cell survival and metastasis are dependent on metabolic reprogramming that is capable of increasing resistance to oxidative and energetic stress. Targeting these two processes can be crucial for cancer progression. Herein, we descri…
Dataset for: MicroRNA-661 modulates redox and metabolic homeostasis in Colon Cancer Open
Cancer cell survival and metastasis are dependent on a metabolic reprogramming able to increase resistance to oxidative and energetic stress. Targeting these two processes can be crucial for cancer progression. Herein we describe the role …
Dataset for: MicroRNA-661 modulates redox and metabolic homeostasis in Colon Cancer Open
Cancer cell survival and metastasis are dependent on a metabolic reprogramming able to increase resistance to oxidative and energetic stress. Targeting these two processes can be crucial for cancer progression. Herein we describe the role …
3’UTR Polymorphism in ACSL1 Gene Correlates with Expression Levels and Poor Clinical Outcome in Colon Cancer Patients Open
Strong evidence suggests that lipid metabolism (LM) has an essential role in tumor growth to support special energetic and structural requirements of tumor cells. Recently, overexpression of LM-related genes, apolipoproteins related to met…