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View article: Reconstructed scar morphology in patient-specific computational heart models has limited impact on the identification of ablation targets through in-silico pace mapping
Reconstructed scar morphology in patient-specific computational heart models has limited impact on the identification of ablation targets through in-silico pace mapping Open
In-silico pace mapping provides a reliable method for identifying VT ablation targets, showing relative insensitivity to scar reconstruction quality. This advantage may support its clinical translation over methods requiring explicit VT si…
View article: In silico pace mapping identifies pacing sites more accurately than inverse body surface potential mapping
In silico pace mapping identifies pacing sites more accurately than inverse body surface potential mapping Open
In silico pace mapping is more accurate than ECGi in detecting paced activation. Performance was optimal when all BSPs were used and reduced during RV apical pacing.
View article: Additional coils mitigate elevated defibrillation threshold in right-sided implantable cardioverter defibrillator generator placement: a simulation study
Additional coils mitigate elevated defibrillation threshold in right-sided implantable cardioverter defibrillator generator placement: a simulation study Open
Aims The standard implantable cardioverter defibrillator (ICD) generator (can) is placed in the left pectoral area; however, in certain circumstances, right-sided cans may be required which may increase defibrillation threshold (DFT) due t…
View article: The effect of scar imaging quality on in-silico pace-mapping of post-infarction ventricular tachycardia
The effect of scar imaging quality on in-silico pace-mapping of post-infarction ventricular tachycardia Open
Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): Wellcome Trust and British Heart Foundation. Background In-silico pacing mapping is a technique which involves using an anatomically-personalised image-b…
View article: Non-invasive localization of post-infarct ventricular tachycardia exit sites to guide ablation planning: a computational deep learning platform utilizing the 12-lead electrocardiogram and intracardiac electrograms from implanted devices
Non-invasive localization of post-infarct ventricular tachycardia exit sites to guide ablation planning: a computational deep learning platform utilizing the 12-lead electrocardiogram and intracardiac electrograms from implanted devices Open
Aims Existing strategies that identify post-infarct ventricular tachycardia (VT) ablation target either employ invasive electrophysiological (EP) mapping or non-invasive modalities utilizing the electrocardiogram (ECG). Their success relie…
View article: Non-invasive delineation of ventricular tachycardia substrates for cardiac stereotactic body radiotherapy: utility of in-silico pace-mapping
Non-invasive delineation of ventricular tachycardia substrates for cardiac stereotactic body radiotherapy: utility of in-silico pace-mapping Open
Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): EPSRC Background Cardiac stereotactive body radiotherapy (CSBRT) is an emerging, non-invasive ablation modality that targets ventricular tachy…
View article: Automated detection of scar-related ventricular tachycardia origins from implanted device electrograms: a combined computational-AI platform
Automated detection of scar-related ventricular tachycardia origins from implanted device electrograms: a combined computational-AI platform Open
Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): EPSRC Background Existing strategies that identify ventricular tachycardia (VT) ablation targets either employ invasive and time-consuming ele…
View article: In-silico optimisation of ICD defibrillation efficacy by modifying lead/can configurations using a cohort of high-resolution whole-torso heart models
In-silico optimisation of ICD defibrillation efficacy by modifying lead/can configurations using a cohort of high-resolution whole-torso heart models Open
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Medical Research Council, UK Background ICD is an effective direct therapy against VT/VF by applying a strong electrical shoc…
View article: Automated Localization of Focal Ventricular Tachycardia From Simulated Implanted Device Electrograms: A Combined Physics–AI Approach
Automated Localization of Focal Ventricular Tachycardia From Simulated Implanted Device Electrograms: A Combined Physics–AI Approach Open
Background: Focal ventricular tachycardia (VT) is a life-threating arrhythmia, responsible for high morbidity rates and sudden cardiac death (SCD). Radiofrequency ablation is the only curative therapy against incessant VT; however, its suc…
View article: In-silico pace-mapping using a detailed whole torso model and implanted electronic device electrograms for more efficient ablation planning
In-silico pace-mapping using a detailed whole torso model and implanted electronic device electrograms for more efficient ablation planning Open
In-silico pace-mapping can be used along with EGMs from implanted devices to localise VT ablation targets in pre-procedural planning.