Silvano Rossini
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View article: Blood product administration in the prehospital setting: a multisociety consensus statement
Blood product administration in the prehospital setting: a multisociety consensus statement Open
The Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI) has led the development of a Good Clinical Practice (GCP) document, engaging multiple scientific societies—including the Italian Society of Transfusio…
View article: Anti-CD38 monoclonal antibody impairs CD34+ mobilization and affects clonogenic potential in multiple myeloma patients.
Anti-CD38 monoclonal antibody impairs CD34+ mobilization and affects clonogenic potential in multiple myeloma patients. Open
Our findings underscore the impact of daratumumab-based treatment on CD34+ mobilization in a real-life, upfront plerixafor-free population of NDMM patients. Higher probability of requiring multiple apheresis occurred among daratumumab-trea…
View article: PF812 INTRAVENOUS IRON SUPPLEMENTATION PROTOCOL FOR POST‐PARTUM ANEMIA
PF812 INTRAVENOUS IRON SUPPLEMENTATION PROTOCOL FOR POST‐PARTUM ANEMIA Open
Background: The World Health Organization (WHO) determines as post‐partum anemia values of harmoglobin (Hb) less than 10 g/dl. In most cases, it's an iron deficiency anemia and affects about the 27% of new mothers and has as a consequence …
View article: PB2445 PRE‐TRANSFUSION IMMUNOHEMATOLOGY TESTING INTERFERENCE WITH DARATUMUMAB: PRELIMINARY EXPERIENCE FROM THE FIRST PATIENTS TREATED AT ASST GOM NIGUARDA
PB2445 PRE‐TRANSFUSION IMMUNOHEMATOLOGY TESTING INTERFERENCE WITH DARATUMUMAB: PRELIMINARY EXPERIENCE FROM THE FIRST PATIENTS TREATED AT ASST GOM NIGUARDA Open
Background: Daratumumab is a human anti‐CD38 monoclonal antibody approved for the treatment of relapsed or refractory multiple myeloma (MM). Due to the physiological presence of the antigen CD38 on the red blood cell (RBC) membrane, Daratu…
View article: PS1589 RETROSPECTIVE ANALYSIS OF HEMOGLOBIN LEVEL IN 500 TRANSFUSION EVENTS AS A STUDY MODEL FOR THE EVALUATION OF TRANSFUSION APPROPRIATENESS
PS1589 RETROSPECTIVE ANALYSIS OF HEMOGLOBIN LEVEL IN 500 TRANSFUSION EVENTS AS A STUDY MODEL FOR THE EVALUATION OF TRANSFUSION APPROPRIATENESS Open
Background: The hemoglobin (Hb) value adopted in the real life setting for the clinical decision of packed red blood cell (RBC) transfusion (transfusion trigger) is sometimes difficult to accurately retrieve and could be different to what …
View article: A Case of Blastic Plasmacytoid Dendritic Cell Neoplasm Extensively Studied by Flow Cytometry and Immunohistochemistry
A Case of Blastic Plasmacytoid Dendritic Cell Neoplasm Extensively Studied by Flow Cytometry and Immunohistochemistry Open
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with aggressive clinical course and poor prognosis. Diagnosis is based on detection of CD4 + CD56 + ,, TCL-1 + , and blood dendritic cell antigen-2/CD303…
View article: Clinical relevance of antiplatelet antibodies and the hepatic clearance of platelets in patients with immune thrombocytopenia
Clinical relevance of antiplatelet antibodies and the hepatic clearance of platelets in patients with immune thrombocytopenia Open
To the editor:
Immune thrombocytopenia (ITP) is an autoimmune disorder whose primary pathogenesis is mediated by Fc receptor (FcR) clearance of antibody-opsonized platelets by spleen macrophages.[1][1] Recently, however, an Fc-independent…