Sofia Shames
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View article: Subclinical Left Ventricular Dysfunction and Ventricular Arrhythmias in Older Adults With Normal Ejection Fraction
Subclinical Left Ventricular Dysfunction and Ventricular Arrhythmias in Older Adults With Normal Ejection Fraction Open
Background Premature ventricular contractions (PVCs) and nonsustained ventricular tachycardia (NSVT) are known to be associated with reduced left ventricular (LV) ejection fraction and adverse outcomes in patients with structural heart dis…
View article: Association of Left Atrial Strain With Ischemic Stroke Risk in Older Adults
Association of Left Atrial Strain With Ischemic Stroke Risk in Older Adults Open
Importance The risk of ischemic stroke is higher among patients with left atrial (LA) enlargement. Left atrial strain (LAε) and LA strain rate (LASR) may indicate LA dysfunction when LA volumes are still normal. The association of LAε with…
View article: Phase 1a/b study of monoclonal antibody CAEL-101 (11-1F4) in patients with AL amyloidosis
Phase 1a/b study of monoclonal antibody CAEL-101 (11-1F4) in patients with AL amyloidosis Open
Systemic immunoglobulin light-chain amyloidosis is characterized by pathologic deposition of immunoglobulin light chains as amyloid fibrils in vital organs, leading to organ impairment and eventual death. That the process is reversible was…
View article: Echocardiographic Characterization of Female Professional Basketball Players in the US
Echocardiographic Characterization of Female Professional Basketball Players in the US Open
In this study, increased cardiac dimensions were frequently observed in WNBA athletes. Both BSA and physiologic remodeling affected cardiac morphologic findings. This study may provide a framework to define the range of athletic cardiac re…
View article: Atherosclerotic Plaques in the Aortic Arch and Subclinical Cerebrovascular Disease
Atherosclerotic Plaques in the Aortic Arch and Subclinical Cerebrovascular Disease Open
Background and Purpose— Aortic arch plaque (AAP) is a risk factor for ischemic stroke, but its association with subclinical cerebrovascular disease is not established. We investigated the association between AAP and subclinical cerebrovasc…