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View article: Fatigue influences embodiment perception and motor performance in multiple sclerosis subjects: a cross-sectional immersive virtual reality study
Fatigue influences embodiment perception and motor performance in multiple sclerosis subjects: a cross-sectional immersive virtual reality study Open
Background Multiple sclerosis (MS) represents a major cause of acquired disability in adults worldwide. Fatigue and upper limb (UL) impairments are common and disabling symptoms in people with MS (pwMS), even in the early stage of the dise…
View article: Effect of exercise on ambulatory supine blood pressure in patients with resistant hypertension and peripheral artery disease with claudication
Effect of exercise on ambulatory supine blood pressure in patients with resistant hypertension and peripheral artery disease with claudication Open
This retrospective study examines the effects of a 6-month home-based walking low-intensity interval training (LIIT) program on systolic blood pressure (SBP) in a cohort of patients with peripheral artery disease (PAD) and controlled (HT) …
View article: A Structured Low-Intensity Home-Based Walking Program to Improve Physical and Mental Functioning After Hospitalization for Severe COVID-19: A Pragmatic Nonrandomized Controlled Trial
A Structured Low-Intensity Home-Based Walking Program to Improve Physical and Mental Functioning After Hospitalization for Severe COVID-19: A Pragmatic Nonrandomized Controlled Trial Open
Background/Objectives: We aimed to test whether home-based low-intensity interval training (LIIT) could be equally or more effective than traditional continuous walking advice (TWA) in a population hospitalized and healed from severe COVID…
View article: Low intensity interval robot-assisted gait training improves mobility in people with progressive multiple sclerosis: the PROGR-EX randomized controlled trial
Low intensity interval robot-assisted gait training improves mobility in people with progressive multiple sclerosis: the PROGR-EX randomized controlled trial Open
ClinicalTrials.gov (NCT06381440).
View article: Action Observation Training for Upper Limb Stroke Rehabilitation: A Pilot Study on the Role of Attention
Action Observation Training for Upper Limb Stroke Rehabilitation: A Pilot Study on the Role of Attention Open
Background: Restoring motor function is crucial for daily life after a stroke. Although patients’ engagement and attention influence motor recovery, these factors are frequently overlooked in rehabilitation interventions. Methods: This pro…
View article: Clinical Utility of Remote Teleassessment of Motor Performance in Individuals With Neurologic Disabilities: A COSMIN Systematic Review
Clinical Utility of Remote Teleassessment of Motor Performance in Individuals With Neurologic Disabilities: A COSMIN Systematic Review Open
Several measurement tools have been identified for remote evaluation of motor performance in people with neurologic disorders, but few of them can be suggested for clinical and scientific purposes. A higher methodological quality of studie…
View article: Exercise therapy to improve mobility, active behaviour and quality of life of chronic kidney disease patients with peripheral artery disease: study protocol for the EXACT-CKDPAD multicentre randomised controlled trial
Exercise therapy to improve mobility, active behaviour and quality of life of chronic kidney disease patients with peripheral artery disease: study protocol for the EXACT-CKDPAD multicentre randomised controlled trial Open
The combination of chronic kidney disease (CKD) and peripheral artery disease (PAD) enhances the already present high cardiovascular risk, exposing the affected patients to unfavourable long-term clinical outcomes. Physical exercise is con…
View article: The effectiveness of combining a home-based Digital motor Telerehabilitation program with conventional therapy in progressive multiple sclerosis: A study protocol for a multicenter, randomized controlled trial
The effectiveness of combining a home-based Digital motor Telerehabilitation program with conventional therapy in progressive multiple sclerosis: A study protocol for a multicenter, randomized controlled trial Open
Objective The primary aim is to evaluate the effectiveness of in-hospital rehabilitation followed by a home-based Digital Telerehabilitation program on mobility versus in-hospital rehabilitation alone in patients with Progressive Multiple …
View article: Pathogenetic Involvement of Autophagy and Mitophagy in Primary Progressive Multiple Sclerosis
Pathogenetic Involvement of Autophagy and Mitophagy in Primary Progressive Multiple Sclerosis Open
Primary progressive multiple sclerosis (PPMS) affects a subset of MS patients and is characterised by continuous progression from the onset. The molecular mechanisms underlying PPMS are poorly understood, and therapeutic options are limite…
View article: The cerebellum and the Mirror Neuron System: A matter of inhibition? From neurophysiological evidence to neuromodulatory implications. A narrative review
The cerebellum and the Mirror Neuron System: A matter of inhibition? From neurophysiological evidence to neuromodulatory implications. A narrative review Open
Mirror neurons show activity during both the execution (AE) and observation of actions (AO). The Mirror Neuron System (MNS) could be involved during motor imagery (MI) as well. Extensive research suggests that the cerebellum is interconnec…
View article: Variations in Cortical Oxygenation by Near-Infrared Spectroscopy According to Head Position after Acute Stroke: The Preliminary Findings of an Observational Study
Variations in Cortical Oxygenation by Near-Infrared Spectroscopy According to Head Position after Acute Stroke: The Preliminary Findings of an Observational Study Open
Background: After ischemic stroke, there is no general consensus on the optimal position for the head of patients in the acute phase. This observational study aimed to measure the variations in cortical oxygenation using noninvasive functi…
View article: A three-year update on guidelines for upper limb robotic rehabilitation after stroke
A three-year update on guidelines for upper limb robotic rehabilitation after stroke Open
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View article: The Cognitive Reserve May Influence Fatigue after Rehabilitation in Progressive Multiple Sclerosis: A Secondary Analysis of the RAGTIME Trial
The Cognitive Reserve May Influence Fatigue after Rehabilitation in Progressive Multiple Sclerosis: A Secondary Analysis of the RAGTIME Trial Open
Cognitive reserve (CR) seems to be an ability to adapt cognitive processes in response to brain disease and may influence rehabilitation outcomes. This is a secondary analysis of the “Robot-Assisted Gait Training versus conventional therap…
View article: The Effectiveness of Paired Associative Stimulation on Motor Recovery after Stroke: A Scoping Review
The Effectiveness of Paired Associative Stimulation on Motor Recovery after Stroke: A Scoping Review Open
Paired associative stimulation (PAS) is a non-invasive brain stimulation technique combining transcranial magnetic stimulation and peripheral nerve stimulation. PAS allows connections between cortical areas and peripheral nerves (C/P PAS) …
View article: Traditional versus progressive robot-assisted gait training in people with multiple sclerosis and severe gait disability: study protocol for the PROGR-EX randomised controlled trial
Traditional versus progressive robot-assisted gait training in people with multiple sclerosis and severe gait disability: study protocol for the PROGR-EX randomised controlled trial Open
Gait disorders are the most frequent symptoms associated to multiple sclerosis (MS). Robot-assisted gait training (RAGT) in people with MS (PwMS) has been proposed as a possible effective treatment option for severe motor disability withou…
View article: Shaping the future: an Italian survey unveils the unmet need to empower physical medicine and rehabilitation professionals with technological skills
Shaping the future: an Italian survey unveils the unmet need to empower physical medicine and rehabilitation professionals with technological skills Open
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View article: Event-related desynchronization during action observation is an early predictor of recovery in subcortical stroke: An EEG study
Event-related desynchronization during action observation is an early predictor of recovery in subcortical stroke: An EEG study Open
Cerebral stroke is a leading cause of death and long-term disability worldwide.Tailoring of therapy approaches has great potential to improve outcomes, but requires a better understanding of specific path of recovery.The most appropriate t…
View article: Role of Smartphone Applications in the Assessment and Management of Fatigue in Patients with Multiple Sclerosis: A Scoping Review
Role of Smartphone Applications in the Assessment and Management of Fatigue in Patients with Multiple Sclerosis: A Scoping Review Open
Fatigue is a common symptom in Multiple Sclerosis (MS), and its assessment depends entirely on patient reports. Importantly, managing MS symptoms is increasingly supported by Digital Health Technology (DHT), which includes Mobile Health Te…
View article: Advancing Public Health through Technological Rehabilitation: Insights from a National Clinician Survey
Advancing Public Health through Technological Rehabilitation: Insights from a National Clinician Survey Open
Introduction: In the evolving healthcare landscape, technology has emerged as a key component in enhancing system efficiency and offering new avenues for patient rehabilitation. Despite its growing importance, detailed information on techn…
View article: The effectiveness of home-based transcranial direct current stimulation on chronic pain: A systematic review and meta-analysis
The effectiveness of home-based transcranial direct current stimulation on chronic pain: A systematic review and meta-analysis Open
Objective As highlighted by the COVID-19 pandemic, identifying strategies for home-based patient management is crucial. As pain is highly prevalent and imposes significant burdens, interest in its remote management is steadily increasing. …
View article: Tele-Mindfulness Program for Mental Health in Previously Hospitalized COVID-19 Patients: A quasi-experimental study
Tele-Mindfulness Program for Mental Health in Previously Hospitalized COVID-19 Patients: A quasi-experimental study Open
Background: Nearly half of subjects after COVID-19 still experience symptoms after 12 weeks, as described in the Post-Covid Syndrome (PCS). Other than the physical alterations perceived, mental health disorders have been frequently reporte…
View article: Fatigue can influence the development of late‐onset pain in post‐<scp>COVID</scp>‐19 syndrome: An observational study
Fatigue can influence the development of late‐onset pain in post‐<span>COVID</span>‐19 syndrome: An observational study Open
Background Late‐onset pain is frequent following COVID‐19, and many pathogenetic mechanisms have been proposed. Identifying the main features of patients may help in designing tailored rehabilitative interventions. Methods We enrolled post…
View article: Anti-Inflammatory and Cortical Responses after Transcranial Direct Current Stimulation in Disorders of Consciousness: An Exploratory Study
Anti-Inflammatory and Cortical Responses after Transcranial Direct Current Stimulation in Disorders of Consciousness: An Exploratory Study Open
Disorders of consciousness (DoC) due to severe traumatic brain injury (TBI) are associated with severe disability and an alteration of cortical activation, angiogenesis, and inflammation, which are crucial elements for behavioural recovery…
View article: Head-Mounted Displays for Upper Limb Stroke Rehabilitation: A Scoping Review
Head-Mounted Displays for Upper Limb Stroke Rehabilitation: A Scoping Review Open
Upper extremity (UE) paresis is one of the most frequent and disabling clinical consequences after stroke. Head-Mounted Displays (HMDs) are wearable virtual reality devices that seem effective in promoting the recovery of functional abilit…
View article: From intensive care to rehabilitation: survey on the satisfaction with care received during prolonged hospitalization for COVID-19 at a northern Italian university hospital.
From intensive care to rehabilitation: survey on the satisfaction with care received during prolonged hospitalization for COVID-19 at a northern Italian university hospital. Open
This survey suggested that COVID-19 patients' healthcare satisfaction was high. Nevertheless, some areas must be improved, such as the communication and involvement of the patients in the decision-making of care and the discussion about me…
View article: A Multimodal Analysis to Explore Upper Limb Motor Recovery at 4 Weeks After Stroke: Insights From EEG and Kinematics Measures
A Multimodal Analysis to Explore Upper Limb Motor Recovery at 4 Weeks After Stroke: Insights From EEG and Kinematics Measures Open
Background. Stroke is a leading cause of death and disability worldwide and there is a very short period of increased synaptic plasticity, fundamental in motor recovery. Thus, it is crucial to acquire data to guide the rehabilitation treat…
View article: Quantitative Comparison of Hand Kinematics Measured with a Markerless Commercial Head-Mounted Display and a Marker-Based Motion Capture System in Stroke Survivors
Quantitative Comparison of Hand Kinematics Measured with a Markerless Commercial Head-Mounted Display and a Marker-Based Motion Capture System in Stroke Survivors Open
Upper-limb paresis is common after stroke. An important tool to assess motor recovery is to use marker-based motion capture systems to measure the kinematic characteristics of patients’ movements in ecological scenarios. These systems are,…
View article: Effects of Exercise, Rehabilitation, and Nutritional Approaches on Body Composition and Bone Density in People with Multiple Sclerosis: A Systematic Review and Meta-Analysis
Effects of Exercise, Rehabilitation, and Nutritional Approaches on Body Composition and Bone Density in People with Multiple Sclerosis: A Systematic Review and Meta-Analysis Open
People with multiple sclerosis (pwMS) are affected by a wide range of disabilities, including a decrease in bone mineral density (BMD) and a worsening of body composition (BC), which negatively impact their quality of life quality. This st…