Sofie Hinrichs
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View article: Proteomic analysis of the urothelial cancer landscape
Proteomic analysis of the urothelial cancer landscape Open
Urothelial bladder cancer (UC) has a wide tumor biological spectrum with challenging prognostic stratification and relevant therapy-associated morbidity. Most molecular classifications relate only indirectly to the therapeutically relevant…
View article: EpCAM tumor specificity and proteoform patterns in urothelial cancer
EpCAM tumor specificity and proteoform patterns in urothelial cancer Open
Background The role of the epithelial cell adhesion molecule (EpCAM) in cancer is still unclear. EpCAM cleavage through regulated intramembrane proteolysis results in fragments which interact with both oncogenic and tumor suppressive pathw…