Soha Namazi
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View article: Therapeutic Effects of Walnuts (Juglans L.): Insights from Randomized Controlled Trials
Therapeutic Effects of Walnuts (Juglans L.): Insights from Randomized Controlled Trials Open
Background: This review elucidates the multifaceted therapeutic effects of Juglans L. (J.), a medicinal plant with a rich heritage in traditional medicine and promising potential in modern healthcare. Methods: A narrative review was conduc…
View article: Effect of Melatonin on Oxaliplatin Induced Neuropathy in Patients Receiving Folfox Chemotherapy Regimens for Stage II–IV Colorectal Cancer: A Randomized, Placebo Controlled, Double Blind Trial
Effect of Melatonin on Oxaliplatin Induced Neuropathy in Patients Receiving Folfox Chemotherapy Regimens for Stage II–IV Colorectal Cancer: A Randomized, Placebo Controlled, Double Blind Trial Open
Background and Aims Peripheral neuropathy is a major side effect of oxaliplatin‐based chemotherapy. The aim of this placebo‐controlled double‐blind randomized study was to evaluate the effect of melatonin on prevention of oxaliplatin induc…
View article: Perioperative Management of Direct Oral Anticoagulants (DOACs) in Elective Surgery Candidates: A Drug Utilization Evaluation (DUE) Study
Perioperative Management of Direct Oral Anticoagulants (DOACs) in Elective Surgery Candidates: A Drug Utilization Evaluation (DUE) Study Open
Background: This study aimed to evaluate physicians' practice regarding perioperative Direct Oral Anticoagulants (DOACs) management in patients undergoing elective procedures and compare it to established institutional standard protocols a…
View article: Design and Evaluation of ACAFiB-APP, a clinical decision support system for anticoagulant considerations in patients with atrial fibrillation
Design and Evaluation of ACAFiB-APP, a clinical decision support system for anticoagulant considerations in patients with atrial fibrillation Open
Not applicable.
View article: Evaluation of the Effect of “Honey Zufa” Herbal Syrup on Cough in Hospitalized Patients With COVID-19: A Double Blind Randomized Clinical Trial
Evaluation of the Effect of “Honey Zufa” Herbal Syrup on Cough in Hospitalized Patients With COVID-19: A Double Blind Randomized Clinical Trial Open
Cough is one of the most prevalent symptoms of COVID-19, affecting over 60% of patients. This symptom significantly diminishes quality of life, causing fatigue, insomnia, dysphonia, musculoskeletal pain, and urinary incontinence. Honey Zuf…
View article: Knowledge and Performance of Iranian Internists Regarding Dyslipidemia According to Lipid Guidelines and their Relationships with Personal and Occupational Characteristics
Knowledge and Performance of Iranian Internists Regarding Dyslipidemia According to Lipid Guidelines and their Relationships with Personal and Occupational Characteristics Open
Background: Lipid metabolism disorders are among the most common metabolic diseases that are increasing globally and are associated with chronic metabolic disturbances. The present study aimed to determine the knowledge and practice of int…
View article: Investigating Myocardial Infarction's Impact on Cytochrome 2c19-Mediated Clopidogrel Activation During Acute and Subacute Phases: A Pharmacokinetic Protocol Study
Investigating Myocardial Infarction's Impact on Cytochrome 2c19-Mediated Clopidogrel Activation During Acute and Subacute Phases: A Pharmacokinetic Protocol Study Open
View article: Immediate hypersensitivity reaction to levetiracetam: a case report study
Immediate hypersensitivity reaction to levetiracetam: a case report study Open
View article: The hypoglycemic effects of <i>Juglans regia</i> L. internal septum in type 2 diabetic patients: A double-blind, randomized, placebo-controlled clinical trial
The hypoglycemic effects of <i>Juglans regia</i> L. internal septum in type 2 diabetic patients: A double-blind, randomized, placebo-controlled clinical trial Open
Introduction: The internal septum of J.regia is traditionally used to control diabetes, and its effectiveness has been shown in animal studies. Accordingly, human clinical trials are needed to confirm its effectiveness on hemoglobin A1c (H…
View article: Iranian Consensus Guideline for Pharmacotherapy with Biologics and Small Molecules Drugs in Adults with Inflammatory Bowel Diseases
Iranian Consensus Guideline for Pharmacotherapy with Biologics and Small Molecules Drugs in Adults with Inflammatory Bowel Diseases Open
Background: Pharmacotherapy with biologics and small molecules, as the more effective therapies for moderate to severe ulcerative colitis (UC) and Crohn’s disease (CD), is complex. Choosing the best methods for their utilization in order t…
View article: Design, Development and Evaluation of an Application based on Clinical Decision Support Systems (CDSS) for Over-The-Counter (OTC) Therapy: An Educational Interventions in Community Pharmacists.
Design, Development and Evaluation of an Application based on Clinical Decision Support Systems (CDSS) for Over-The-Counter (OTC) Therapy: An Educational Interventions in Community Pharmacists. Open
The OTC therapy application developed in this study will help Persian-speaking pharmacists to increase their knowledge and pharmaceutical skills.
View article: Trimethoprim/sulfamethoxazole desensitization in an HIV-positive patient with previous Stevens-Johnson syndrome; a failed study
Trimethoprim/sulfamethoxazole desensitization in an HIV-positive patient with previous Stevens-Johnson syndrome; a failed study Open
View article: The approach of Iranian clinical pharmacists in the treatment of dyslipidemia based on international guidelines
The approach of Iranian clinical pharmacists in the treatment of dyslipidemia based on international guidelines Open
Introduction: Optimal treatment of dyslipidemia is a top priority in the prevention of cardiovascular diseases. For this purpose, clinicians in Iran usually refer to four current international guidelines. The aim of this study was to asses…
View article: Effect of melatonin on oxaliplatin induced neuropathy in patients receiving FOLFOX and XELOX chemotherapy regimens for stage II-IV colorectal cancer; A randomized, placebo controlled, double blind trial
Effect of melatonin on oxaliplatin induced neuropathy in patients receiving FOLFOX and XELOX chemotherapy regimens for stage II-IV colorectal cancer; A randomized, placebo controlled, double blind trial Open
Purpose Peripheral neuropathy is a major side effect of oxaliplatin-based chemotherapy. The aim of this placebo-controlled double-blind randomized study was to evaluate the effect of melatonin on prevention of oxaliplatin induced periphera…
View article: Evaluation of important human CYP450 isoforms and P-glycoprotein phenotype changes and genotype in type 2 diabetic patients, before and after treatment, by using Geneva cocktail
Evaluation of important human CYP450 isoforms and P-glycoprotein phenotype changes and genotype in type 2 diabetic patients, before and after treatment, by using Geneva cocktail Open
The present study evaluates the influence of type 2 diabetes (T2D) on important CYP450 isoforms and P-glycoprotein (P-gp) transporter activities before and 3 months after intensifying treatment regimen of 40 patients. Results have been com…
View article: <b>Effect of <i>Juglans regia</i> L. Ridge on Blood Lipids in Type 2 Diabetic Patients with Dyslipidemia: A Double-blind Placebo-Controlled Randomized Clinical Trial </b>
<b>Effect of <i>Juglans regia</i> L. Ridge on Blood Lipids in Type 2 Diabetic Patients with Dyslipidemia: A Double-blind Placebo-Controlled Randomized Clinical Trial </b> Open
Background: Dyslipidemia and diabetes mellitus are two important risk factors for coronary artery disease and stroke. Traditionally, herbal remedies like walnut were used to treat dyslipidemia. The study aimed to evaluate the effect of Jug…
View article: Assessment of Pharmacists’ Confidence When Consulting Patients on Anticoagulants: A Cross-Sectional Study in Iran
Assessment of Pharmacists’ Confidence When Consulting Patients on Anticoagulants: A Cross-Sectional Study in Iran Open
Backgrounds: The pharmacists have a crucial role in providing pharmaceutical care to patients who receive anticoagulants. This study was conducted to evaluate the pharmacists’ confidence in pharmaceutical consultation in the field of antic…
View article: FLOT; To Be Treated as a Highly Emetogenic Regimen or a Moderately Emetogenic One? Comparison of the Emetogenic Potential of FLOT versus FOLFOX and TAC Regimens
FLOT; To Be Treated as a Highly Emetogenic Regimen or a Moderately Emetogenic One? Comparison of the Emetogenic Potential of FLOT versus FOLFOX and TAC Regimens Open
PurposeThe current study aimed at investigating the efficacy of aprepitant-containing triple antiemetic regimen in FLOT (Fluorouracil+Leucovorin+Oxaliplatin+Docetaxel) recipients as well as the emetogenic potential of FLOT regimen, through…
View article: Designing, Implementation, and Evaluation of an Online Modular Course on Patient Education and Counseling at the Community Pharmacy
Designing, Implementation, and Evaluation of an Online Modular Course on Patient Education and Counseling at the Community Pharmacy Open
Background: The role of pharmacists has evolved from drug provision to patient care. Considering the Doctor of Pharmacy curriculum in Iran and the small number of programs on pharmaceutical care, Iranian pharmacy graduates may not be able …
View article: The Effects of Three ABCG2 Polymorphisms on Outcome of Central Nervous System Relapses in Iranian Children With Acute Lymphoblastic Leukemia Receiving High Dose Methotrexate
The Effects of Three ABCG2 Polymorphisms on Outcome of Central Nervous System Relapses in Iranian Children With Acute Lymphoblastic Leukemia Receiving High Dose Methotrexate Open
Methotrexate (MTX) is the main drug for the treatment of childhood acute lymphoblastic leukemia (ALL). ABCG2 pump is the main transporter of MTX on BBB. Our aim was to investigate the possible relationship between three polymorphisms of th…
View article: Melatonin effect on platelet count in patients with liver disease.
Melatonin effect on platelet count in patients with liver disease. Open
Melatonin may increase platelet count and inhibit thrombocytopenia in patients with liver disease; however, more investigations are needed to confirm the current results.
View article: A Pilot Randomized, Clinical Trial of the Anti-pruritus Effect of Melatonin in Patients with Chronic Liver Disease.
A Pilot Randomized, Clinical Trial of the Anti-pruritus Effect of Melatonin in Patients with Chronic Liver Disease. Open
Pruritus is one of the disturbing complications induced by chronic liver disease (CLD), bearing a negative impact on patient quality of life and potentially resulting in early liver transplants. Given the main role of the autotaxin enzyme …
View article: <b>Evaluation of the Association between Trough and Area Under the Curve to Minimum Inhibitory Concentration Ratio (AUC24/MIC) of Vancomycin in Infected Patients with Methicillin Resistant <i>Staphylococcus aureus</i> (MRSA)</b>
<b>Evaluation of the Association between Trough and Area Under the Curve to Minimum Inhibitory Concentration Ratio (AUC24/MIC) of Vancomycin in Infected Patients with Methicillin Resistant <i>Staphylococcus aureus</i> (MRSA)</b> Open
Background: The recent studies emphasized on the correlation of vancomycin antibacterial effect with pharmacokinetics properties such as the area under the curve/minimum inhibitory concentration (AUC24/MIC) ≥400 and serum trough level 15-2…
View article: Validity and Reliability of Persian Version of 12-Item Pruritus Severity Score Questionnaire in Patients with Chronic Liver Disease and Pruritus.
Validity and Reliability of Persian Version of 12-Item Pruritus Severity Score Questionnaire in Patients with Chronic Liver Disease and Pruritus. Open
BACKGROUND Currently, there is no published questionnaire translated in the Persian language for pruritus evaluation in patients with chronic liver disease. Therefore, it would be well worth having a valid and reliable Persian questionnair…
View article: Rapid and specific chromatography method on monolithic RP-column for determination of high-dose methotrexate pharmacokinetics in sera of cancer patients admitted to Shiraz Amir Hospital
Rapid and specific chromatography method on monolithic RP-column for determination of high-dose methotrexate pharmacokinetics in sera of cancer patients admitted to Shiraz Amir Hospital Open
Introduction: methotrexate (MTX) is a routinely used antifolate for the treatment of solid tumors and hematologic malignancies. However, high-dose MTX can lead to severe side effects and the patients are required to receive leucovorin resc…
View article: Evaluation and Management of Drug-Drug Interactions in Patients Hospitalized in Nephrology and Post-Transplant Wards in a Teaching Hospital
Evaluation and Management of Drug-Drug Interactions in Patients Hospitalized in Nephrology and Post-Transplant Wards in a Teaching Hospital Open
Background: Kidney transplant patients usually take a combination of medications after transplantation; hence, medication safety becomes an important issue in order to maintain the new organ working properly. To evaluate the incidence and …
View article: Herbal Treatments to Gain Weight as the Potential Cause of Portal Vein Thrombosis and Hepatic Damage: A Case Report
Herbal Treatments to Gain Weight as the Potential Cause of Portal Vein Thrombosis and Hepatic Damage: A Case Report Open
This research aimed to assess the effect of a specific herbal agent to gain weight as the potential cause of Portal Vein Thrombosis (PVT) and hepatic damage. In this study, we reported a 24-year-old man who referred to the Tehran Universit…
View article: Evaluating the effect of type 2 diabetes mellitus on CYP450 enzymes and P-gp activities, before and after glycemic control: A protocol for a case–control pharmacokinetic study
Evaluating the effect of type 2 diabetes mellitus on CYP450 enzymes and P-gp activities, before and after glycemic control: A protocol for a case–control pharmacokinetic study Open
View article: Association of ABCB1 Gene Polymorphisms and Clopidogrel Responsiveness in Iranian Patients undergoing Percutaneous Coronary Intervention.
Association of ABCB1 Gene Polymorphisms and Clopidogrel Responsiveness in Iranian Patients undergoing Percutaneous Coronary Intervention. Open
Clopidogrel is an antiplatelet agent currently used for preventing stent thrombosis. Despite certain clinical benefits of clopidogrel in patients undergoing percutaneous coronary intervention (PCI), adequate antiplatelet effect has not bee…
View article: <p>Economic Burden Of Inappropriate Empiric Antibiotic Therapy: A Report From Southern Iran</p>
Economic Burden Of Inappropriate Empiric Antibiotic Therapy: A Report From Southern Iran Open
Arman Sadatsharifi,1 Mohammad-Ali Davarpanah,2 Soha Namazi,3 Shaghayegh Mottaghi,1 Laleh Mahmoudi1 1Department of Clinical Pharmacy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran; 2Shiraz HIV/AIDS Research Centre,…