Soharth Hasnat
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View article: Structural insights into AVR-Rmg8 recognition mechanisms by the wheat blast resistance gene Rmg8
Structural insights into AVR-Rmg8 recognition mechanisms by the wheat blast resistance gene Rmg8 Open
Wheat blast disease, caused by the Triticum pathotype of Magnaporthe oryzae (MoT), poses a significant threat to global food security. The blast resistance gene Rmg8 , recently isolated from a hexaploid wheat cultivar, strongly confers res…
View article: Probiotic potential and antimicrobial efficacy of a dairy isolate, Enterococcus faecium MBBL3
Probiotic potential and antimicrobial efficacy of a dairy isolate, Enterococcus faecium MBBL3 Open
View article: Draft-genome sequence of <i>Bacillus subtilis</i> SS17, a promising shrimp probiotic candidate
Draft-genome sequence of <i>Bacillus subtilis</i> SS17, a promising shrimp probiotic candidate Open
We describe a promising shrimp probiotic candidate Bacillus subtilis SS17, which was isolated from the intestine of a healthy tiger shrimp, Penaeus monodon . The de novo assembly resulted in an estimated chromosome size of 4,042,212 bases …
View article: Computational investigation unveils pathogenic LIG3 non-synonymous mutations and therapeutic targets in acute myeloid leukemia
Computational investigation unveils pathogenic LIG3 non-synonymous mutations and therapeutic targets in acute myeloid leukemia Open
Single nucleotide polymorphisms (SNPs) in DNA repair genes can impair protein structure and function, contributing to disease development, including cancer. Non-synonymous SNPs (nsSNPs) in the LIG3 gene are linked to genomic instability an…
View article: High throughput screening identifies potential inhibitors targeting trimethoprim resistant DfrA1 protein in Klebsiella pneumoniae and Escherichia coli
High throughput screening identifies potential inhibitors targeting trimethoprim resistant DfrA1 protein in Klebsiella pneumoniae and Escherichia coli Open
The DfrA1 protein provides trimethoprim resistance in bacteria, especially Klebsiella pneumoniae and Escherichia coli, by modifying dihydrofolate reductase, which reduces the binding efficacy of the antibiotic. This study identified inhibi…
View article: Computational investigation unveils pathogenic LIG3 non-synonymous mutations and therapeutic targets in acute myeloid leukemia
Computational investigation unveils pathogenic LIG3 non-synonymous mutations and therapeutic targets in acute myeloid leukemia Open
Single nucleotide polymorphisms (SNPs) in DNA repair genes can impair protein structure and function, contributing to disease development, including cancer. Non-synonymous SNPs (nsSNPs) in the LIG3 gene are linked to genomic instability an…
View article: Draft genome sequencing of a multidrug-resistant and virulent <i>Escherichia coli</i> strain isolated from milk of a cow with clinical mastitis
Draft genome sequencing of a multidrug-resistant and virulent <i>Escherichia coli</i> strain isolated from milk of a cow with clinical mastitis Open
We present the draft genome of Escherichia coli strain MBBL3, a virulent and antimicrobial-resistant pathogen isolated from the milk of a cow suffering from clinical mastitis. The assembled genome spans 4,713,190 base pairs, organized into…
View article: <i>Enterococcus faecium</i> MBBL3 Exhibits Promising Probiotic Potential and Antimicrobial Efficacy Against Bovine Mastitis-Associated <i>Escherichia coli and Klebsiella pneumoniae</i>
<i>Enterococcus faecium</i> MBBL3 Exhibits Promising Probiotic Potential and Antimicrobial Efficacy Against Bovine Mastitis-Associated <i>Escherichia coli and Klebsiella pneumoniae</i> Open
Enterococcus faecium , a promising probiotic, combats pathogens, supports gut health, strengthens immunity, and provides a natural approach to address the escalating global challenge of antimicrobial resistance. This study aimed to investi…
View article: Genomic insights into the probiotic potential and genes linked to gallic acid metabolism in Pediococcus pentosaceus MBBL6 isolated from healthy cow milk
Genomic insights into the probiotic potential and genes linked to gallic acid metabolism in Pediococcus pentosaceus MBBL6 isolated from healthy cow milk Open
Pediococcus pentosaceus is well known for its probiotic properties, including roles in improving health, antimicrobial production, and enhancing fermented food quality. This study aimed to comprehensively analyze the whole genome of P . pe…
View article: In-silico identification and characterization of effector proteins in the rice blast pathogen Magnaporthe oryzae
In-silico identification and characterization of effector proteins in the rice blast pathogen Magnaporthe oryzae Open
View article: Natural Bacteriocins as Potential Drug Candidates Targeting Core Proteins in Mastitis Pathogens of Dairy Cattle
Natural Bacteriocins as Potential Drug Candidates Targeting Core Proteins in Mastitis Pathogens of Dairy Cattle Open
Mastitis poses a major challenge in the dairy industry, with rising antibiotic-resistant strains underscoring the urgent need for alternative antimicrobial strategies. This study aimed to (i) identify essential core proteins in clinical ma…
View article: A Framework for Accurate Prediction of Plastic-Degrading Enzymes using Convolutional Neural Networks
A Framework for Accurate Prediction of Plastic-Degrading Enzymes using Convolutional Neural Networks Open
The growing accumulation of plastic waste presents a significant environmental challenge, necessitating innovative approaches to mitigate its impact. Enzymatic degradation has emerged as a promising solution for addressing plastic pollutio…