Sohum Sheth
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View article: Surgical Approaches to Retinal Gene Therapy: 2025 Update
Surgical Approaches to Retinal Gene Therapy: 2025 Update Open
Gene therapy offers a promising new frontier in the treatment of inherited and acquired retinal disease. This review describes the current surgical delivery approaches for gene therapy to the retina—subretinal, suprachoroidal, and intravit…
View article: Surgical Approaches to Retinal Gene Therapy: 2025 Update
Surgical Approaches to Retinal Gene Therapy: 2025 Update Open
Gene therapy offers a promising new frontier in the treatment of inherited and acquired retinal disease. This review describes the current surgical delivery approaches for gene therapy to the retina — subretinal, suprachoroidal, intravitre…
View article: High-density lipoproteins. Part 2. Impact of disease states on functionality
High-density lipoproteins. Part 2. Impact of disease states on functionality Open
In contrast to low-density lipoproteins which are atherogenic, high-density lipoproteins (HDL) have been conceptualized as beneficial modulators of adverse pathophysiological phenomena along arterial walls. The HDLs are characterized by hi…
View article: Acute Angle Closure in an 18-Year-Old Due to Plateau Iris
Acute Angle Closure in an 18-Year-Old Due to Plateau Iris Open
In this case report, we describe a rare case of acute angle closure in an 18-year-old African-American female, attributed to plateau iris. The patient had no significant medical or ocular history and presented with high right-eye pressure,…
View article: Risk Stratification Using Cardiac Imaging: A Comprehensive Review
Risk Stratification Using Cardiac Imaging: A Comprehensive Review Open
There are numerous cardiac imaging modalities which aid in the diagnosis and management of coronary artery disease (CAD). Each modality has variable efficacy in detecting stenosis and stratifying risk among those with CAD. Clinicians must …
View article: The protective role of GLP-1 in neuro-ophthalmology
The protective role of GLP-1 in neuro-ophthalmology Open
Despite recent advancements in the field of neuro-ophthalmology, the rising rates of neurological and ophthalmological conditions, mismatches between supply and demand of clinicians, and an aging population underscore the urgent need to ex…
View article: Endovascular Chemotherapy: Selective Targeting for Brain Cancer
Endovascular Chemotherapy: Selective Targeting for Brain Cancer Open
Establishing an effective and robust management option for brain cancers has proven to bean elusive challenge for the fields of neurosurgery and neuro-oncology. Despite decades of research efforts to improve treatment outcomes and increase…
View article: Diabetes Mellitus Management in the Context of Cranial Tumors
Diabetes Mellitus Management in the Context of Cranial Tumors Open
The study of the relationship between cancer and diabetes mellitus (DM) has been under investigation for many decades. Particularly in the field of neurology and neurosurgery, increasing emphasis has been put on the examination of comorbid…
View article: Diabetes Mellitus Management in the Context of Cranial Tumors
Diabetes Mellitus Management in the Context of Cranial Tumors Open
The study of the relationship between cancer and diabetes mellitus (DM) has been under investigation for many decades. Particularly in the field of neurology and neurosurgery, increasing emphasis has been put on the examination of comorbid…