Soichiro Ishihara
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View article: Dosimetric analysis and clinical outcomes including adverse events in postoperative breast cancer irradiation involving the internal mammary lymph node region using Hybrid VMAT
Dosimetric analysis and clinical outcomes including adverse events in postoperative breast cancer irradiation involving the internal mammary lymph node region using Hybrid VMAT Open
Background Although radiotherapy including the internal mammary lymph nodes (IMN) after breast surgery improves the prognosis of breast cancer, it may also increase radiation exposure to the heart and lungs due to the expanded irradiation …
View article: Relationship between fibrosis induced by preoperative chemoradiotherapy and real-time tissue elastography of internal anal sphincter
Relationship between fibrosis induced by preoperative chemoradiotherapy and real-time tissue elastography of internal anal sphincter Open
Background It has been suggested that chemoradiotherapy may cause fibrosis of the internal anal sphincter, resulting in sclerosis. However, no report has quantitatively investigated this relationship by using real-time tissue elastography.…
View article: Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2024 for the treatment of colorectal cancer
Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2024 for the treatment of colorectal cancer Open
The number of deaths from colorectal cancer in Japan continues to rise, with over 50,000 deaths recorded in 2018. In the 2024 edition, revisions to all aspects of treatment were undertaken, with corrections and additions made based on know…
View article: Analysis of clinicopathological features and oncological outcomes of ulcerative colitis-associated colorectal cancer based on macroscopic classification
Analysis of clinicopathological features and oncological outcomes of ulcerative colitis-associated colorectal cancer based on macroscopic classification Open
Purpose Few studies have reported the association of macroscopic classification with clinicopathological characteristics and prognosis of ulcerative colitis-associated colorectal cancer (UC-CRC), unlike sporadic CRC. In this study, we aime…
View article: Significance of positional correction of planned couch angles with the ExacTrac system
Significance of positional correction of planned couch angles with the ExacTrac system Open
This study evaluated the benefits of the ExacTrac system for non-coplanar beams in brain stereotactic radiotherapy (SRT) by comparing pre- and post-X-ray verification (XV) positioning data. Data from 62 patients undergoing brain SRT were a…
View article: Relationship between fibrosis induced by preoperative chemoradiotherapy and real-time tissue elastography of the internal anal sphincter
Relationship between fibrosis induced by preoperative chemoradiotherapy and real-time tissue elastography of the internal anal sphincter Open
Purpose: Chemoradiotherapy may cause fibrosis of the internal anal sphincter, resulting in sclerosis. However, no report has quantitatively investigated this relationship by using real-time tissue elastography. This study aimed to clarify …
View article: Comparison between free breathing and deep inspiration breath hold in left-sided breast cancer treatment
Comparison between free breathing and deep inspiration breath hold in left-sided breast cancer treatment Open
DIBH is an effective treatment technique for reducing the dose to the heart and the relative irradiated left lung volume for left-sided breast cancer, although the absolute irradiated left lung volume is increased.
View article: Association of urinary dysfunction after lower rectal cancer surgery with renal function: a single-center study
Association of urinary dysfunction after lower rectal cancer surgery with renal function: a single-center study Open
View article: Laparoscopy-assisted partial cecum resection vs. ileocecal resection for non-malignant appendiceal neoplasms
Laparoscopy-assisted partial cecum resection vs. ileocecal resection for non-malignant appendiceal neoplasms Open
Purpose Preoperative pathological diagnosis of appendiceal tumors is difficult due to their anatomical nature. Although lymph node metastasis is rare in low-grade appendiceal mucinous neoplasms (LAMN), there is a risk of a positive surgica…
View article: Comprehensive analysis of retrograde infection of a prophylactic pelvic drain in rectal cancer surgery: a retrospective cohort study
Comprehensive analysis of retrograde infection of a prophylactic pelvic drain in rectal cancer surgery: a retrospective cohort study Open
Purpose The role of prophylactic pelvic drains in rectal surgery remains controversial. A significant concern is the risk of retrograde drain infection, a type of surgical site infection occurring at the drain insertion site. To address th…
View article: A pilot study of gut mucosal and faecal microbiota in rectal cancer: associations with histological response and adverse events following preoperative chemoradiotherapy
A pilot study of gut mucosal and faecal microbiota in rectal cancer: associations with histological response and adverse events following preoperative chemoradiotherapy Open
Aim Preoperative chemoradiotherapy (CRT) is administered for locally advanced rectal cancer (LARC); however, its efficacy and toxicity vary among patients. This study aimed to elucidate the relationship between the gut microbiota and the e…
View article: Extramammary Paget Disease in the Peristomal Skin of an Ileal Conduit Reconstructed With a Pedicled Anterolateral Thigh Flap
Extramammary Paget Disease in the Peristomal Skin of an Ileal Conduit Reconstructed With a Pedicled Anterolateral Thigh Flap Open
Summary: An ileal conduit is the most commonly used urinary diversion following radical cystectomy. Malignancy of the ileal conduit rarely occurs, and Paget disease has not been reported in the peristomal skin of an ileal conduit. Herein, …
View article: Does surgical intervention contribute to survival for patients with para‐aortic lymph node metastasis from colorectal cancer?
Does surgical intervention contribute to survival for patients with para‐aortic lymph node metastasis from colorectal cancer? Open
Aims There is a lack of compelling evidence supporting the benefit of surgical resection for para‐aortic lymph node metastasis (PALNM) from colorectal cancer (CRC). We aimed to investigate the true impact of surgical resection on survival …
View article: Knowledge-Based Planning and Multi-criteria Optimization Combination with Volumetric Modulated Arc Therapy for Patients with Laryngeal Cancer
Knowledge-Based Planning and Multi-criteria Optimization Combination with Volumetric Modulated Arc Therapy for Patients with Laryngeal Cancer Open
Purpose: This study aimed to evaluate the effectiveness of knowledge-based planning (KBP) with additional multi-criteria optimization (MCO) for the volumetric modulated arc therapy (VMAT) of the larynx. Methods: Twenty previously treated V…
View article: Preoperative chemoradiotherapy with the TEGAFIRI regimen achieves significant local control in locally advanced rectal cancer
Preoperative chemoradiotherapy with the TEGAFIRI regimen achieves significant local control in locally advanced rectal cancer Open
Purpose This study aims to evaluate both the short- and long-term outcomes of preoperative chemoradiotherapy (CRT) using the tegafur-uracil/calcium folinate/irinotecan (TEGAFIRI) regimen in patients with locally advanced rectal cancer (LAR…
View article: Performance evaluation of MVision AI Contour+ in gastric MALT lymphoma segmentation
Performance evaluation of MVision AI Contour+ in gastric MALT lymphoma segmentation Open
View article: Clinical features by disease duration in ulcerative colitis‐associated cancers
Clinical features by disease duration in ulcerative colitis‐associated cancers Open
Aim Ulcerative colitis (UC) is a known contributor to the development of colitis‐associated cancer (CAC), although the exact mechanism remains to be elucidated. CAC typically presents as a flat type macroscopically and manifests histologic…
View article: Comparative microRNA signatures based on liquid biopsy to identify lymph node metastasis in T1 colorectal cancer patients undergoing upfront surgery or endoscopic resection
Comparative microRNA signatures based on liquid biopsy to identify lymph node metastasis in T1 colorectal cancer patients undergoing upfront surgery or endoscopic resection Open
After endoscopic resection of T1 colorectal cancer (CRC) with a high risk of lymph node metastasis (LNM), additional surgery is required. However, the actual frequency of LNM based on conventional risk factors is less than 16%. There is a …
View article: Clinical significance of preoperative Glasgow prognostic score in patients with colorectal cancer and synchronous peritoneal metastases
Clinical significance of preoperative Glasgow prognostic score in patients with colorectal cancer and synchronous peritoneal metastases Open
Background Chemotherapy is the typical choice for treating colorectal cancer with synchronous peritoneal metastases. Nonetheless, surgical resection may be chosen if the metastases are resectable. Unfortunately, there is no reliable preope…
View article: Factors Affecting the Prognosis after Primary Tumor Resection for Patients with Metastatic Colorectal Cancer with Synchronous Peritoneal Metastasis: A Multi-center, Prospective, Observational Study
Factors Affecting the Prognosis after Primary Tumor Resection for Patients with Metastatic Colorectal Cancer with Synchronous Peritoneal Metastasis: A Multi-center, Prospective, Observational Study Open
In patients with mCRC-SPM, postoperative complications are infrequent for P1 with localized peritoneal dissemination, and PTR may be considered as aggressive treatment. Factors including age ≥75 years, rectal cancer, presence of liver meta…
View article: 2023 National Clinical Database Annual Report by the Japan Surgical Society
2023 National Clinical Database Annual Report by the Japan Surgical Society Open
View article: Treatment outcomes and prognostic factors in patients with colorectal cancer and synchronous lung metastases in the conversion therapy era
Treatment outcomes and prognostic factors in patients with colorectal cancer and synchronous lung metastases in the conversion therapy era Open
Purpose The Japanese Grade Classification based on the status of pulmonary and mesenteric nodal metastases and the presence of extrapulmonary metastases had a prognostic value in patients with colorectal lung metastases previously. Because…
View article: Update on the Diagnosis and Treatment of IBD-Associated Cancer
Update on the Diagnosis and Treatment of IBD-Associated Cancer Open
View article: Recurrent Tumor in Colorectal Cancer Requiring Combined Resection of Iliac or Femoral Vessels: Report of Four Cases
Recurrent Tumor in Colorectal Cancer Requiring Combined Resection of Iliac or Femoral Vessels: Report of Four Cases Open
It is difficult to accurately evaluate whether a recurrent tumor from colorectal cancer directly invades vessels using preoperative imaging. However, the combined resection of recurrent tumor and vessels may be required to achieve R0 resec…
View article: Higher Processed Blood Volume of Granulocyte and Monocyte Adsorption Apheresis Ameliorates Long-Term Disease Activity in Ulcerative Colitis Patients
Higher Processed Blood Volume of Granulocyte and Monocyte Adsorption Apheresis Ameliorates Long-Term Disease Activity in Ulcerative Colitis Patients Open
Greater processed blood volume of GMA per patient body weight may be associated with a lower 1-year exacerbation rate in UC patients.
View article: Preoperative sarcopenia negatively impacts short‐ and long‐term outcomes of rectal cancer: A propensity score‐matched analysis
Preoperative sarcopenia negatively impacts short‐ and long‐term outcomes of rectal cancer: A propensity score‐matched analysis Open
Aim Sarcopenia is associated with poor postoperative outcomes in various cancers; however, limited evidence is available for rectal cancer. Therefore, the present study examined the effects of skeletal muscle mass on the short‐ and long‐te…
View article: Role of Adjuvant Chemotherapy After Surgical Resection of Paraaortic Lymph Node Metastasis from Colorectal Cancer—A Multicenter Retrospective Study
Role of Adjuvant Chemotherapy After Surgical Resection of Paraaortic Lymph Node Metastasis from Colorectal Cancer—A Multicenter Retrospective Study Open
Background Surgical removal of metastasized paraaortic lymph nodes (PALNs) can prolong the survival of certain patients with colorectal cancer (CRC). However, the role of postoperative chemotherapy in such patients remains unknown. Patient…
View article: Nomograms Predicting Survival, Recurrence and Beneficiary Identification of Adjuvant Chemotherapy in Treatment-naïve Patients with Rectal Cancer who Underwent Upfront Curative Resection: A multi-institutional study
Nomograms Predicting Survival, Recurrence and Beneficiary Identification of Adjuvant Chemotherapy in Treatment-naïve Patients with Rectal Cancer who Underwent Upfront Curative Resection: A multi-institutional study Open
Objective: To create and validate nomograms predicting overall survival and recurrence in treatment-naïve rectal cancer (RC) patients who underwent upfront surgery. Background: Although multidisciplinary treatment is standard for locally a…
View article: Prognostic value of surgical treatment in elderly patients with ulcerative colitis‐associated colorectal cancer: A subanalysis of a nationwide Japanese multicenter study
Prognostic value of surgical treatment in elderly patients with ulcerative colitis‐associated colorectal cancer: A subanalysis of a nationwide Japanese multicenter study Open
Aim Our study aimed to examine the characteristics of elderly patients diagnosed with ulcerative colitis‐associated colorectal cancer (UAC) and evaluate the impact of surgical intervention on prognosis. Methods A total of 1086 patients dia…
View article: The Development of Volumetric Quantitative Evaluation Software for Assessing Respiratory-Induced Target Motion
The Development of Volumetric Quantitative Evaluation Software for Assessing Respiratory-Induced Target Motion Open
Purpose We developed a volumetric quantitative evaluation software called vector volume histogram (VVH) to evaluate respiratory-induced organ motion using deformable image registration (DIR). Methods The B-spline-based DIR algorithm was us…