Solomon Assefa
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View article: Nutritional, anti-nutritional, physicochemical and functional properties of raw and roasted Salvia Schimperi (Lamiaceae) seeds: Ethiopian indigenous plant
Nutritional, anti-nutritional, physicochemical and functional properties of raw and roasted Salvia Schimperi (Lamiaceae) seeds: Ethiopian indigenous plant Open
Though, Ethiopia is home to a variety of edible plants, such as Salvia schimperi (S. schimperi) seeds, which have been traditionally consumed in the community, there is a paucity of information concerning the nutritional composition of S. …
View article: Efficacy of eHealth Technologies on Medication Adherence in Patients With Acute Coronary Syndrome: Systematic Review and Meta-Analysis
Efficacy of eHealth Technologies on Medication Adherence in Patients With Acute Coronary Syndrome: Systematic Review and Meta-Analysis Open
Background Suboptimal adherence to cardiac pharmacotherapy, recommended by the guidelines after acute coronary syndrome (ACS) has been recognized and is associated with adverse outcomes. Several randomized controlled trials (RCTs) have sho…
View article: Exploring Lessons from Regional Maintenance Workshop to Enhance Medical Equipment Functionality in Ethiopia
Exploring Lessons from Regional Maintenance Workshop to Enhance Medical Equipment Functionality in Ethiopia Open
Background WHO estimates that around 50% of medical equipment in developing countries are not functional. In Ethiopia, lack of proper management of medical equipment has limited the capacity of health institutions to deliver adequate healt…
View article: Efficacy of eHealth Technologies on Medication Adherence in Patients With Acute Coronary Syndrome: Systematic Review and Meta-Analysis (Preprint)
Efficacy of eHealth Technologies on Medication Adherence in Patients With Acute Coronary Syndrome: Systematic Review and Meta-Analysis (Preprint) Open
BACKGROUND Suboptimal adherence to cardiac pharmacotherapy, recommended by the guidelines after acute coronary syndrome (ACS) has been recognized and is associated with adverse outcomes. Several randomized controlled trials (RCTs) have sh…
View article: AI for climate impacts: applications in flood risk
AI for climate impacts: applications in flood risk Open
In recent years there has been a surge of interest in the potential of Artificial Intelligence (AI) to address the global threat of climate change. Here, we consider climate change applications, and review the ability of AI technologies to…
View article: Multi-environment evaluation of malt sorghum in semi-arid areas of Northeast Ethiopia
Multi-environment evaluation of malt sorghum in semi-arid areas of Northeast Ethiopia Open
Multi-environment trials are important to identify desirable genotypes. A field experiment was carried out at four locations for two years to evaluate thirteen malt-sorghum genotypes together with two checks so as to identify stable and hi…
View article: In vivo antimalarial activity of crude fruit extract of Capsicum frutescens var. minima (Solanaceae) against Plasmodium berghei infected mice
In vivo antimalarial activity of crude fruit extract of Capsicum frutescens var. minima (Solanaceae) against Plasmodium berghei infected mice Open
Background: The alarming spread of drug resistance to current antimalarial agents is threatening malaria controlling efforts. This, consequently, urged the scientific community to discover novel antimalarial drugs. Successful and most pote…
View article: Antimalarial Activity of Aqueous and 80% Methanol Crude Seed Extracts and Solvent Fractions of <i>Schinus molle</i> Linnaeus (<i>Anacardiaceae</i>) in <i>Plasmodium berghei</i>-Infected Mice
Antimalarial Activity of Aqueous and 80% Methanol Crude Seed Extracts and Solvent Fractions of <i>Schinus molle</i> Linnaeus (<i>Anacardiaceae</i>) in <i>Plasmodium berghei</i>-Infected Mice Open
Background . Malaria is among the leading causes of mortality and morbidity. Moreover, the emergence of resistance to antimalarial drugs is a major problem in controlling the disease. This makes the development of novel antimalarial drugs …
View article: Old and Recent Advances in Life Cycle, Pathogenesis, Diagnosis, Prevention, and Treatment of Malaria Including Perspectives in Ethiopia
Old and Recent Advances in Life Cycle, Pathogenesis, Diagnosis, Prevention, and Treatment of Malaria Including Perspectives in Ethiopia Open
Malaria, caused by apicomplexan parasite, is an old disease and continues to be a major public health threat in many countries. This article aims to present different aspects of malaria including causes, pathogenesis, prevention, and treat…
View article: <i>In Vivo</i> Antimalarial Activity of 80% Methanol and Aqueous Bark Extracts of <i>Terminalia brownii</i> Fresen. (Combretaceae) against <i>Plasmodium berghei</i> in Mice
<i>In Vivo</i> Antimalarial Activity of 80% Methanol and Aqueous Bark Extracts of <i>Terminalia brownii</i> Fresen. (Combretaceae) against <i>Plasmodium berghei</i> in Mice Open
Background . Despite a substantial scientific progress over the past two decades, malaria continues to be a worldwide burden. Evergrowing resistance towards the currently available antimalarial drugs is a challenge to combat malaria. Medic…
View article: Yield stability and adaptability of lowland sorghum (<i>Sorghum bicolor</i> (L.) Moench) in moisture-deficit areas of Northeast Ethiopia
Yield stability and adaptability of lowland sorghum (<i>Sorghum bicolor</i> (L.) Moench) in moisture-deficit areas of Northeast Ethiopia Open
Genotype-environment interaction (GxE) is a common phenomenon in sorghum. The effect of GxE can be reduced by identifying stable genotypes across environments. An investigation was conducted to study yield stability and adaptability of 13 …
View article: <i>In Vivo</i> Antimalarial Activity of Crude Fruit Extract of <i>Capsicum frutescens</i> Var. Minima (Solanaceae) against <i>Plasmodium berghei</i> ‐Infected Mice
<i>In Vivo</i> Antimalarial Activity of Crude Fruit Extract of <i>Capsicum frutescens</i> Var. Minima (Solanaceae) against <i>Plasmodium berghei</i> ‐Infected Mice Open
Background . The alarming spread of parasite resistance to current antimalarial agents is threatening malaria controlling efforts. This, consequently, urged the scientific community to discover novel antimalarial drugs. Successful and most…
View article: Assessment of Magnitude and Associated Factors of Emergence Delirium in the Post Anesthesia Care Unit at Tikur Anbesa Specialized Hospital, Ethiopia
Assessment of Magnitude and Associated Factors of Emergence Delirium in the Post Anesthesia Care Unit at Tikur Anbesa Specialized Hospital, Ethiopia Open
The magnitude of emergence delirium is high and it is associated with older age, substance abuse, premedication with benzodiazepine, excessive blood loss postoperative pain and longer PACU stay.
View article: Bacteriophages and their applications: general aspects and a new insight in Ethiopia
Bacteriophages and their applications: general aspects and a new insight in Ethiopia Open
Bacteriophages, having a variety of function in different disciplines, are viruses that invade bacterial cells. Phages are enormously essential to the ecology and evolution of bacteria, and have huge impacts on global weather patterns. Due…
View article: Wheat production and breeding in Sub-Saharan Africa
Wheat production and breeding in Sub-Saharan Africa Open
Purpose This paper aims to review the current status of wheat production, farming systems, production constraints and wheat demand-supply chain analysis; the role of international and national breeding programs and their approaches in whea…
View article: Technical efficiency and yield gap of smallholder wheat producers in Ethiopia: A Stochastic Frontier Analysis
Technical efficiency and yield gap of smallholder wheat producers in Ethiopia: A Stochastic Frontier Analysis Open
Improving technical efficiency of smallholder farmers is one of the options to increase wheat yield in developing countries. This paper assesses technical efficiency, factors for inefficiency and the yield gap due to technical inefficiency…
View article: In Vitro Antibacterial Activity of Selected Medicinal Plants in the Traditional Treatment of Skin and Wound Infections in Eastern Ethiopia
In Vitro Antibacterial Activity of Selected Medicinal Plants in the Traditional Treatment of Skin and Wound Infections in Eastern Ethiopia Open
Background . External infections involving the skin and wound are the most frequent complications affecting humans and animals. Medicinal plants play great roles in the treatment of skin and wound infections. This study was aimed to evalua…
View article: Adaptability and genotype-environment interaction of finger millet (Eleusine coracana (L.) Gaertn) varieties in North Eastern Ethiopia
Adaptability and genotype-environment interaction of finger millet (Eleusine coracana (L.) Gaertn) varieties in North Eastern Ethiopia Open
An experiment was conducted to study the adaptability and genotype × environment interaction of finger millet varieties in the north eastern part of Ethiopia. Eight finger millet varieties and a local check were tested at Sirinka, Kobo, an…
View article: Drug resistance in African animal trypanosomes: A review
Drug resistance in African animal trypanosomes: A review Open
Animal African trypanosmiasis (AAT) is the most important factor contributing to the sub potential performance of livestock. AAT is caused by Trypanosoma congolense, Trypanosoma vivax and Trypanosoma brucei. Chemotherapy and chemoprophylax…
View article: Antimalarial Potential of the Leaf Exudate of Aloe macrocarpa Todaro and its Major Constituents against Plasmodium berghei
Antimalarial Potential of the Leaf Exudate of Aloe macrocarpa Todaro and its Major Constituents against Plasmodium berghei Open
Background:Aloe macrocarpa Todaro is one of the Aloe species in Ethiopia where its leaf exudate is traditionally used for the treatment of various ailments, including malaria. Methods:Two pure compounds namely aloin and aloinoside were iso…
View article: <i>In Vivo</i> Antimalarial Activity of the 80% Methanolic Root Bark Extract and Solvent Fractions of <i>Gardenia ternifolia</i> Schumach. & Thonn. (Rubiaceae) against <i>Plasmodium berghei</i>
<i>In Vivo</i> Antimalarial Activity of the 80% Methanolic Root Bark Extract and Solvent Fractions of <i>Gardenia ternifolia</i> Schumach. & Thonn. (Rubiaceae) against <i>Plasmodium berghei</i> Open
Background . Evolution of antimalarial drug resistance makes the development of new drugs a necessity. Important source in search of such drugs is medicinal plants. Gardenia ternifolia plant is used in Ethiopian traditional medicine for th…
View article: Assessment of vocational training programmes on mushroom farming and p.h.t of mushroom organized for urban women of gamaharia block in saraikela kharsawan district
Assessment of vocational training programmes on mushroom farming and p.h.t of mushroom organized for urban women of gamaharia block in saraikela kharsawan district Open
KVKs are always conducting skill oriented vocational training programmers on various topics in agriculture and in allied subjects. Through these programmes the participants acquire knowledge and skill for their self employment and income g…
View article: Phytochemical screening and toxicity profiles of crude extracts of Cissus quadrangularis L. and Solunum incanum L. in mice
Phytochemical screening and toxicity profiles of crude extracts of Cissus quadrangularis L. and Solunum incanum L. in mice Open
Plant derived bioactive molecules are always in demand and are the main focus of research. Despite the growing market demand for herbal medicines, safety of medicinal plants is still a concern. The present work aimed at generating prelimin…
View article: Analysis of wheat commercialization in Ethiopia: The case of SARD-SC wheat project innovation platform sites
Analysis of wheat commercialization in Ethiopia: The case of SARD-SC wheat project innovation platform sites Open
In Ethiopia, wheat is becoming an essential source of income for farmers even though it is still a fundamental food crop. While the major proportion is kept for consumption, farmers sell part of their wheat produce. The main objectives of …
View article: <i>In Vitro</i> Anthelmintic Activity of Crude Extracts of Aerial Parts of<i> Cissus quadrangularis</i> L. and Leaves of<i> Schinus molle</i> L. against<i> Haemonchus contortus</i>
<i>In Vitro</i> Anthelmintic Activity of Crude Extracts of Aerial Parts of<i> Cissus quadrangularis</i> L. and Leaves of<i> Schinus molle</i> L. against<i> Haemonchus contortus</i> Open
Background . Haemonchus contortus, the causative agent of Haemonchosis, is the most economically important parasite in small ruminant production. Control with chemotherapy has not been successful due to rapid emergence of drug-resistant st…