Soňa Smetanová
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View article: Virion content unpacked by long-read sequencing: stress-induced changes in transmitted staphylococcal mobilome due to phage-satellite interactions
Virion content unpacked by long-read sequencing: stress-induced changes in transmitted staphylococcal mobilome due to phage-satellite interactions Open
The evolution of the virulence and antibiotic resistance of staphylococci, important opportunistic pathogens, is strongly determined by their mobilome, which can spread by phage virions or small-headed particles resulting from the hijackin…
View article: Changing pattern of exposure to polycyclic aromatic hydrocarbons over time in the Central European population
Changing pattern of exposure to polycyclic aromatic hydrocarbons over time in the Central European population Open
Background Temporal trends of chemicals in the population are key to identifying changing sources of chemicals and determining the effectiveness of various legislative measures. Objective The present study focused on time comparisons to ex…
View article: Compatibility of antimicrobial preservatives with therapeutic bacteriophages of the genera Pbunavirus and Kayvirus
Compatibility of antimicrobial preservatives with therapeutic bacteriophages of the genera Pbunavirus and Kayvirus Open
Implementing bacteriophages into dosage forms is a significant step for the practical application of phage therapy. While designing a dosage form, bacteriophages as active ingredients may be exposed to excipients, guaranteeing microbial qu…
View article: Sampling frequency matters: mapping of the healthy infants' gut microbiome during the first year of life
Sampling frequency matters: mapping of the healthy infants' gut microbiome during the first year of life Open
Background Previous studies described the impact of various early life events on the developing gut environment of infants. Nevertheless, a comprehensive understanding of the time frame of the response of the healthy microbiome to specific…
View article: Fecal tryptophan metabolite profiling in newborns in relation to microbiota and antibiotic treatment
Fecal tryptophan metabolite profiling in newborns in relation to microbiota and antibiotic treatment Open
In the first days of life, the newborns’ intestinal microbiota develops simultaneously with the intestinal gut barrier and follows intestinal immunity. The mode of delivery shows significant impact on microbial development and, thus, the i…
View article: Additional file 3 of Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study
Additional file 3 of Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study Open
Additional file 3. Bacterial genera in the dust and nasopharyngeal samples. * Number of occurrences of the specific genus in the dust (n = 44)/nasopharyngeal samples (n = 44). One nasopharyngeal sample collected in the afternoon was exclud…
View article: Additional file 5 of Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study
Additional file 5 of Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study Open
Additional file 5. Results of differential abundance testing between groups. Only genera with at least unadjusted p-value ≤ 0.05 are displayed. Specific groups and statistical tests used are summarized on the Overview sheet.
View article: Additional file 8 of Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study
Additional file 8 of Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study Open
Additional file 8. ASV table nonchimeric. Np, nasopharyngeal sample; D, dust sample; Mor, morning samples; Aft, afternoon samples; NEO, maternity hospital (n = 8); ENT, pediatric hospital (n = 6); RCX, research center (n = 8).
View article: Additional file 2 of Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study
Additional file 2 of Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study Open
Additional file 2. Bacterial phyla in the dust and nasopharyngeal samples. * Number of occurrences of the specific phylum in the dust (n = 44)/nasopharyngeal samples (n = 44). One nasopharyngeal sample collected in the afternoon was exclud…
View article: Intragastric administration of low-dose rotenone post-colitis exacerbates damage to the nigrostriatal dopaminergic system in Parkinson’s disease: The pace accelerates even more
Intragastric administration of low-dose rotenone post-colitis exacerbates damage to the nigrostriatal dopaminergic system in Parkinson’s disease: The pace accelerates even more Open
Background The contribution of gastrointestinal (GI) inflammation and local exposure to neurotoxins in the gut offers the most in-depth explanation of Parkinson’s disease (PD) etiopathogenesis through abnormal accumulation and spreading of…
View article: Profiling Tryptophan Catabolites of Human Gut Microbiota and Acute-Phase Protein Levels in Neonatal Dried Blood Specimens
Profiling Tryptophan Catabolites of Human Gut Microbiota and Acute-Phase Protein Levels in Neonatal Dried Blood Specimens Open
National screening programs use dried blood specimens to detect metabolic disorders or aberrant protein functions that are not clinically evident in the neonatal period. Similarly, gut microbiota metabolites and immunological acute-phase p…
View article: High colonisation by probiotic Escherichia coli A0 34/86 strain is associated with a less diverse microbiome related to children’s age
High colonisation by probiotic Escherichia coli A0 34/86 strain is associated with a less diverse microbiome related to children’s age Open
Probiotic supplementation in childhood serves as an additional source of bacterial colonisers and represents an opportunity to beneficially manipulate the intestinal microbiome. Differences in the ability of probiotic strains to colonise t…