Sonal S. Munsiff
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View article: Reply to Wilson <i>et al.</i>: The 4-Month Isoniazid, Rifapentine, Moxifloxacin, and Pyrazinamide Treatment Regimen for Drug-Susceptible Pulmonary Tuberculosis: A Word of Caution
Reply to Wilson <i>et al.</i>: The 4-Month Isoniazid, Rifapentine, Moxifloxacin, and Pyrazinamide Treatment Regimen for Drug-Susceptible Pulmonary Tuberculosis: A Word of Caution Open
View article: Case Report of <i>Aerococcus urinae</i> Tricuspid Valve Endocarditis, New York, USA
Case Report of <i>Aerococcus urinae</i> Tricuspid Valve Endocarditis, New York, USA Open
We report a case of a 61-year-old man in New York, USA, who had recurrent Aerococcus urinae endocarditis that first involved his native and then his bioprosthetic tricuspid valve. We demonstrate that a complicated A. urinae endocarditis ca…
View article: “Bilateral Capnocytophaga Canimorsus Periprosthetic Joint Infections in an Immunocompromised Patient: A Case Report and Literature Review”
“Bilateral Capnocytophaga Canimorsus Periprosthetic Joint Infections in an Immunocompromised Patient: A Case Report and Literature Review” Open
A 63-year-old dog owner with bilateral total knee arthroplasties developed periprosthetic joint infections bilaterally due to Capnocytophaga canimorsus (C canimorsus), a bacterium commonly found in the saliva of dogs and cats…
View article: P-1876. Implementing a Transitions-of-Care Pilot for Patient Discharge on Outpatient Parenteral Antimicrobial Therapy (OPAT): Feasibility and Impact with Focus on Social Determinants of Health (SDOH)
P-1876. Implementing a Transitions-of-Care Pilot for Patient Discharge on Outpatient Parenteral Antimicrobial Therapy (OPAT): Feasibility and Impact with Focus on Social Determinants of Health (SDOH) Open
Background Complex care coordination and requirement for rapid acquisition of advanced clinical skills at transition from inpatient settings to OPAT may lead to negative experiences and adverse outcomes for patients, with disproportionate …
View article: Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis: An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline
Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis: An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline Open
Background: On the basis of recent clinical trial data for the treatment of drug-susceptible and drug-resistant tuberculosis (TB), the American Thoracic Society, U.S. Centers for Disease Control and Prevention, European Respiratory …
View article: HepB-CpG vs HepB-Alum Vaccine in People With HIV and Prior Vaccine Nonresponse
HepB-CpG vs HepB-Alum Vaccine in People With HIV and Prior Vaccine Nonresponse Open
Importance Nonresponse to hepatitis B vaccine is common among people with HIV, resulting in vulnerability to infection with hepatitis B virus (HBV). Objective To compare the seroprotection response achieved with a 2-dose (noninferiority, 1…
View article: Corrigendum to “Tuberculosis screening for patients on biologic Medications: A Single-Center experience and Society guideline Review, Monroe County, New York, 2018–2021” [J. Clin. Tuberc. Other Mycobact. Dis. 36 (2024) 100460]
Corrigendum to “Tuberculosis screening for patients on biologic Medications: A Single-Center experience and Society guideline Review, Monroe County, New York, 2018–2021” [J. Clin. Tuberc. Other Mycobact. Dis. 36 (2024) 100460] Open
[This corrects the article DOI: 10.1016/j.jctube.2024.100460.].
View article: Effects of Respiratory Isolation for Tuberculosis to Reduce Community-based Transmission: A Systematic Review
Effects of Respiratory Isolation for Tuberculosis to Reduce Community-based Transmission: A Systematic Review Open
Background Respiratory isolation of people with pulmonary tuberculosis (TB), including after treatment initiation, is used to prevent community-based transmission; yet guidelines on duration are limited and implementation is heterogeneous.…
View article: Epidemiology of nontuberculous mycobacteria in the Finger Lakes region of New York
Epidemiology of nontuberculous mycobacteria in the Finger Lakes region of New York Open
Clinical-epidemiologic data for all nontuberculous mycobacteria isolated in the 9 County Finger Lakes region of NY from 226 patients between 04/01/2018-03/31/2020 were retrospectively analyzed. Only 51% of patients meeting diagnostic crite…
View article: Epidemiology and Clinical Characteristics of Ocular Tuberculosis in the United States, 1993–2019
Epidemiology and Clinical Characteristics of Ocular Tuberculosis in the United States, 1993–2019 Open
Background Data regarding ocular tuberculosis (OTB) in the United States have not been previously reported. We evaluated trends of OTB compared with other extrapulmonary TB (EPTB). Methods We estimated the proportion of all EPTB cases (wit…
View article: The Uncharted Patterns of Antibiotic Prescribing in Urology Ambulatory Practices: A Four-Year Analysis
The Uncharted Patterns of Antibiotic Prescribing in Urology Ambulatory Practices: A Four-Year Analysis Open
Background: Urinary tract infections (UTIs) represent a prevalent indication for outpatient antibiotic usage, yet limited data exist regarding antibiotic prescriptions within urology specialties. This study aimed to assess antibiotic presc…
View article: Tuberculosis screening for patients on biologic Medications: A Single-Center experience and Society guideline Review, Monroe County, New York, 2018–2021
Tuberculosis screening for patients on biologic Medications: A Single-Center experience and Society guideline Review, Monroe County, New York, 2018–2021 Open
View article: Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV
Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV Open
Importance Cardiovascular disease (CVD) is increased in people with HIV (PWH) and is characterized by premature noncalcified coronary plaque. In the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE), pitavastatin reduced major …
View article: Making the EHR Work for You—Modifications of an Electronic Health Record System to Improve Tracking and Management of Patients Receiving Outpatient Parenteral Antibiotic Therapy
Making the EHR Work for You—Modifications of an Electronic Health Record System to Improve Tracking and Management of Patients Receiving Outpatient Parenteral Antibiotic Therapy Open
Background Managing the complex needs of outpatient parenteral antibiotic therapy (OPAT) patients is challenging and time-consuming. We describe development of multimodal interventions to facilitate patient management within an Epic® (Epic…
View article: 342. Evaluation of Patient Satisfaction with Outpatient Parenteral Antibiotic Therapy (OPAT) at a University Medical Center
342. Evaluation of Patient Satisfaction with Outpatient Parenteral Antibiotic Therapy (OPAT) at a University Medical Center Open
Background With the expansion of OPAT care over recent years, new devices such as elastomeric balls have been added to the available drug delivery options, which also include syringe, electronic pumps and gravity bags. The primary objectiv…
View article: 357. High Rate of Adverse Events in Patients Receiving Oral Antimicrobials Under a COpAT Monitoring Protocol
357. High Rate of Adverse Events in Patients Receiving Oral Antimicrobials Under a COpAT Monitoring Protocol Open
Background Oral linezolid (LZD), trimethoprim sulfamethoxazole (SXT), voriconazole (VRC), and itraconazole (ITC) are used often for prolonged durations and are associated with an array of adverse events (AEs). Establishing specific protoco…
View article: 1890. Evaluating the effect of respiratory isolation for TB on patient- and public health-important outcomes- a systematic review
1890. Evaluating the effect of respiratory isolation for TB on patient- and public health-important outcomes- a systematic review Open
Background The duration of respiratory isolation for infectious tuberculosis (TB) is based on limited data and expert opinion. Yet the impact of isolation on persons with TB and public health programs is significant. This systematic review…
View article: 2216. Orthopedic Provider Adherence to American Academy of Orthopedic Surgeons (AAOS) Guidelines for Dental Prophylaxis in Total Joint Replacement
2216. Orthopedic Provider Adherence to American Academy of Orthopedic Surgeons (AAOS) Guidelines for Dental Prophylaxis in Total Joint Replacement Open
Background Antibiotic prophylaxis before dental procedures (DP) in patients with prosthetic joints has not been shown to decrease the risk of prosthetic joint infections (PJI). Current American Academy of Orthopedic Surgeons (AAOS) guideli…
View article: Daily fosfomycin versus levofloxacin for complicated urinary tract infections
Daily fosfomycin versus levofloxacin for complicated urinary tract infections Open
Fosfomycin, approved in the United States only for cystitis, is an attractive alternative for oral treatment of outpatient complicated urinary tract infections (cUTIs) as it has antimicrobial activity against most common uropathogens. The …
View article: Implementation of Bedaquiline, Pretomanid, and Linezolid in the United States: Experience Using a Novel All-Oral Treatment Regimen for Treatment of Rifampin-Resistant or Rifampin-Intolerant Tuberculosis Disease
Implementation of Bedaquiline, Pretomanid, and Linezolid in the United States: Experience Using a Novel All-Oral Treatment Regimen for Treatment of Rifampin-Resistant or Rifampin-Intolerant Tuberculosis Disease Open
Background Rifampin-resistant tuberculosis is a leading cause of morbidity worldwide; only one-third of persons start treatment, and outcomes are often inadequate. Several trials demonstrate 90% efficacy using an all-oral, 6-month regimen …
View article: A Case of Multiple Skin Lesions After Lipodissolve<sup>TM</sup> Injection
A Case of Multiple Skin Lesions After Lipodissolve<sup>TM</sup> Injection Open
Mycobacterium abscessus (M. abscessus) is a rapidly growing nontuberculous mycobacterium commonly found in soil and water. It can cause localized infection when inoculated during surgical or cosmetic procedures. We describe a case of a pat…
View article: 413. Cost effectiveness of rectal screening for ESBL producing organism in preventing urosepsis following transrectal prostate biopsy
413. Cost effectiveness of rectal screening for ESBL producing organism in preventing urosepsis following transrectal prostate biopsy Open
Background Urosepsis following transrectal ultrasound guided prostate biopsy (TRUS PB) occurs in 0.3-3.1% of patients. Our center gives ciprofloxacin and ceftriaxone prophylaxis. With rise in urinary pathogens resistant to fluoroquinolones…
View article: 1428. Clinical Characteristics and Management of Nontuberculous Mycobacterial Infections in the Finger Lakes Region of New York
1428. Clinical Characteristics and Management of Nontuberculous Mycobacterial Infections in the Finger Lakes Region of New York Open
Background Nontuberculous Mycobacteria (NTM) are ubiquitous in the environment and associated with pulmonary and extra-pulmonary infections. Evaluation and treatment of these infections is complex and prolonged, involving oral, intravenous…
View article: Systematic review of antibiotic stewardship interventions for urinary tract infection management in the ambulatory setting
Systematic review of antibiotic stewardship interventions for urinary tract infection management in the ambulatory setting Open
Background: Urinary tract infections (UTIs) are common indications for antibiotics in ambulatory setting, and inappropriate use is prevalent. Fluoroquinolones account for 40% of antibiotics prescribed for uncomplicated UTIs, despite clinic…
View article: Mycobacterium szulgai cavitary lung disease progression over a three year period – A case report
Mycobacterium szulgai cavitary lung disease progression over a three year period – A case report Open
View article: Safety and immunogenicity of a SARS-CoV-2 recombinant protein vaccine with AS03 adjuvant in healthy adults: interim findings from a phase 2, randomised, dose-finding, multi-centre study
Safety and immunogenicity of a SARS-CoV-2 recombinant protein vaccine with AS03 adjuvant in healthy adults: interim findings from a phase 2, randomised, dose-finding, multi-centre study Open
Summary Background This study evaluated the safety and immunogenicity of an AS03-adjuvanted SARS-CoV-2 recombinant protein candidate vaccine, CoV2 preS dTM. Methods This Phase 2, modified double-blind, parallel-group study ( NCT04762680 ) …
View article: Locally recurrent primary cutaneous coccidioidomycosis
Locally recurrent primary cutaneous coccidioidomycosis Open
View article: Simplifying outpatient antibiotic stewardship
Simplifying outpatient antibiotic stewardship Open
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View article: Rate of broad-spectrum antibiotic overuse in patients receiving outpatient parenteral antibiotic therapy (OPAT)
Rate of broad-spectrum antibiotic overuse in patients receiving outpatient parenteral antibiotic therapy (OPAT) Open
Broad-spectrum antibiotics with once-daily dosing are often chosen for outpatient parenteral antibiotic therapy (OPAT) due to convenience even when narrower-spectrum antibiotics are appropriate. At our institution, up to 50% of select broa…
View article: 217. Broad Spectrum Antibiotic use in Outpatient Parenteral Antibiotic Therapy (OPAT): Opportunities for Antibiotic Stewardship
217. Broad Spectrum Antibiotic use in Outpatient Parenteral Antibiotic Therapy (OPAT): Opportunities for Antibiotic Stewardship Open
Background Broad-spectrum antibiotics are often chosen for OPAT due to the convenience of once daily dosing. Current literature suggests that at least 20–30% of these regimens could be narrowed, but this has not been well-defined. Methods …