Sonali D. Advani
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View article: Multisociety guidance for infection prevention and control in nursing homes
Multisociety guidance for infection prevention and control in nursing homes Open
This multisociety guidance was endorsed by SHEA, APIC, IDSA, PALTmed, and AGS. It provides recommendations for infection prevention and control (IPC) in the context of the complexity of nursing home care in the United States: increased med…
View article: Urinary tract infection in adults: gaps in current guidelines – opinions from an international multidisciplinary panel and relevance to clinical practice
Urinary tract infection in adults: gaps in current guidelines – opinions from an international multidisciplinary panel and relevance to clinical practice Open
Purpose Although urinary tract infections (UTIs) are one of the most common infections encountered in clinical practice, many challenges remain with respect to classification and management. The purpose of this report is to discuss key iss…
View article: State-of-the-Art Review: Recurrent Uncomplicated Urinary Tract Infections in Women
State-of-the-Art Review: Recurrent Uncomplicated Urinary Tract Infections in Women Open
Over 50% of adult women experience at least 1 urinary tract infection (UTI) in their lifetime, and almost one-quarter of them will experience a recurrent UTI (rUTI). Recurrent UTI is defined as ≥2 UTIs in a 6-month period or ≥3 UTIs in 12 …
View article: Use of Machine Learning to Assess the Management of Uncomplicated Urinary Tract Infection
Use of Machine Learning to Assess the Management of Uncomplicated Urinary Tract Infection Open
Importance Uncomplicated urinary tract infection (UTI) is a common indication for outpatient antimicrobial therapy. National guidelines for the management of uncomplicated UTI were published in 2011, but the extent to which they align with…
View article: P-1577. Healthcare utilization, antibiotic spectrum index, and outcomes associated with complicated urinary tract infections in the United States
P-1577. Healthcare utilization, antibiotic spectrum index, and outcomes associated with complicated urinary tract infections in the United States Open
Background Despite a recent increase in the burden of complicated urinary tract infections (cUTI), contemporary data on healthcare utilization, outcomes and antimicrobial use related to cUTIs are lacking. We describe healthcare utilization…
View article: P-884. A Scenario-Based Survey of Clinician Recommendations for Follow-up Blood Cultures in Patients with Varying Risk of Persistent Gram-Negative Bacteremia
P-884. A Scenario-Based Survey of Clinician Recommendations for Follow-up Blood Cultures in Patients with Varying Risk of Persistent Gram-Negative Bacteremia Open
Background Studies examining the impact of follow-up blood cultures (FUBCs) in patients with gram-negative bacteremia (GNB) have shown mixed results. In practice, FUBCs are variably obtained. Understanding practice variation and motivation…
View article: Assessing the burden of outpatient urinary tract infections in the United States: analysis of nationwide ambulatory data (2016–2019)
Assessing the burden of outpatient urinary tract infections in the United States: analysis of nationwide ambulatory data (2016–2019) Open
We conducted an analysis of a nationwide survey of US physician offices between 2016 and 2019 and calculated annualized prevalence rates of urinary tract infections (UTIs). During the 3-year study period, UTI was the most common infection …
View article: Implementing the Infectious Diseases Society of America Antimicrobial Stewardship Core Curriculum: Survey Results and Real-World Strategies to Guide Fellowship Programs
Implementing the Infectious Diseases Society of America Antimicrobial Stewardship Core Curriculum: Survey Results and Real-World Strategies to Guide Fellowship Programs Open
Background The Infectious Diseases Society of America (IDSA) developed the Core Antimicrobial Stewardship (AS) Curriculum to meet the increasing demand for infectious diseases (ID) providers with AS expertise. Notable diversity in implemen…
View article: A call to action: the SHEA research agenda to combat healthcare-associated infections
A call to action: the SHEA research agenda to combat healthcare-associated infections Open
View article: Performance of Urinalysis Parameters in Predicting Urinary Tract Infection: Does One Size Fit All?
Performance of Urinalysis Parameters in Predicting Urinary Tract Infection: Does One Size Fit All? Open
In a multihospital cohort study of 3392 patients, positive urinalysis parameters had poor positive predictive value for diagnosing urinary tract infection (UTI). Combined urinalysis parameters (pyuria or nitrite) performed better than pyur…
View article: ICE volume 45 issue 4 Cover and Front matter
ICE volume 45 issue 4 Cover and Front matter Open
View article: Bacteremia From a Presumed Urinary Source in Hospitalized Adults With Asymptomatic Bacteriuria
Bacteremia From a Presumed Urinary Source in Hospitalized Adults With Asymptomatic Bacteriuria Open
Importance Guidelines recommend withholding antibiotics in asymptomatic bacteriuria (ASB), including among patients with altered mental status (AMS) and no systemic signs of infection. However, ASB treatment remains common. Objectives To d…
View article: Proposing the “Continuum of UTI” for a Nuanced Approach to Diagnosis and Management of Urinary Tract Infections
Proposing the “Continuum of UTI” for a Nuanced Approach to Diagnosis and Management of Urinary Tract Infections Open
Our data suggest the need to reframe our conceptual model of UTI vs ASB to reflect the full spectrum of clinical presentations, acknowledge the diagnostic uncertainty faced by frontline clinicians, and promote a nuanced approach to diagnos…
View article: Diagnostic stewardship to improve patient outcomes and healthcare-associated infection (HAI) metrics
Diagnostic stewardship to improve patient outcomes and healthcare-associated infection (HAI) metrics Open
Diagnostic stewardship seeks to improve ordering, collection, performance, and reporting of tests. Test results play an important role in reportable HAIs. The inclusion of HAIs in public reporting and pay for performance programs has highl…
View article: Evidence gaps among systematic reviews examining the relationship of race, ethnicity, and social determinants of health with adult inpatient quality measures
Evidence gaps among systematic reviews examining the relationship of race, ethnicity, and social determinants of health with adult inpatient quality measures Open
Background: The field of healthcare epidemiology is increasingly focused on identifying, characterizing, and addressing social determinants of health (SDOH) to address inequities in healthcare quality. To identify evidence gaps, we examine…
View article: Five steps to high quality antimicrobial stewardship research
Five steps to high quality antimicrobial stewardship research Open
The escalating threat of antimicrobial resistance (AMR) necessitates impactful, reproducible, and scalable antimicrobial stewardship strategies. This review addresses the critical need to enhance the quality of antimicrobial stewardship in…
View article: Inpatient clinicians’ approach to diagnosis of urinary tract infections in older adults using the COM-B model: a qualitative assessment
Inpatient clinicians’ approach to diagnosis of urinary tract infections in older adults using the COM-B model: a qualitative assessment Open
Our interviews of inpatient clinicians (physicians, physician assistants) modeled after the Capability, Opportunity, and Motivation Model of Behavior model revealed opportunity and motivation as important drivers for overdiagnosis and over…
View article: Effect of automated identification of antimicrobial stewardship opportunities for suspected urinary tract infections
Effect of automated identification of antimicrobial stewardship opportunities for suspected urinary tract infections Open
Objective: We aimed to determine whether automated identification of antibiotic targeting suspected urinary tract infection (UTI) shortened the time to antimicrobial stewardship (AS) intervention. Design: Retrospective before-and-after stu…
View article: 2818. Investigating Urinalysis Criteria that Predict UTI: Impact of age, sex, and urine culture thresholds
2818. Investigating Urinalysis Criteria that Predict UTI: Impact of age, sex, and urine culture thresholds Open
Background Urinalysis (UA) results are used by clinicians and laboratories to aid in the diagnosis of UTI. However, optimal UA parameters have not been systematically investigated or validated for different populations. Our objectives were…
View article: 2847. Healthcare utilization among older adults hospitalized with complicated urinary tract infections in the United States
2847. Healthcare utilization among older adults hospitalized with complicated urinary tract infections in the United States Open
Background Healthcare utilization for complicated urinary tract infections (cUTI) is increasing in recent years, especially among older adults due to comorbidities and immunosuppression. However, healthcare utilization and inpatient antibi…
View article: 117P Genomic landscape of biliary tract cancers from India show distinct geographic variation
117P Genomic landscape of biliary tract cancers from India show distinct geographic variation Open
View article: Introduction to <i>A Compendium of Strategies to Prevent Healthcare-Associated Infections In Acute-Care Hospitals: 2022 Updates</i>
Introduction to <i>A Compendium of Strategies to Prevent Healthcare-Associated Infections In Acute-Care Hospitals: 2022 Updates</i> Open
Since the initial publication of A Compendium of Strategies to Prevent Healthcare-Associated Infections in Acute Care Hospitals in 2008, the prevention of healthcare-associated infections (HAIs) has continued to be a national priority. Pro…
View article: Executive Summary: A Compendium of Strategies to Prevent Healthcare-Associated Infections in Acute-Care Hospitals: 2022 Updates
Executive Summary: A Compendium of Strategies to Prevent Healthcare-Associated Infections in Acute-Care Hospitals: 2022 Updates Open
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View article: Strategies to prevent catheter-associated urinary tract infections in acute-care hospitals: 2022 Update
Strategies to prevent catheter-associated urinary tract infections in acute-care hospitals: 2022 Update Open
and purpose The intent of this document is to highlight practical recommendations in a concise format designed to assist physicians, nurses, and infection preventionists at acute-care hospitals in implementing and prioritizing their cathet…
View article: ICE volume 44 issue 8 Cover and Front matter
ICE volume 44 issue 8 Cover and Front matter Open
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
View article: Prevalence of and risk factors for bacteremic UTIs in hospitalized adults without definitive signs or symptoms of UTI
Prevalence of and risk factors for bacteremic UTIs in hospitalized adults without definitive signs or symptoms of UTI Open
Background: IDSA guidelines recommend withholding treatment in patients with asymptomatic bacteriuria in the absence of systemic signs of infection. However, some patients with bacteriuria may not be able to express symptoms either due to …
View article: Proposing the “continuum of UTI” for a nuanced approach to antimicrobial stewardship
Proposing the “continuum of UTI” for a nuanced approach to antimicrobial stewardship Open
Background: Historically, diagnosis of urinary tract infections (UTIs) has been divided into 3 categories based on symptoms and urine culture results: not UTI, asymptomatic bacteriuria (ASB), or UTI. However, some populations (eg, older ad…
View article: Disparities in central line-associated bloodstream infection and catheter-associated urinary tract infection rates: An exploratory analysis
Disparities in central line-associated bloodstream infection and catheter-associated urinary tract infection rates: An exploratory analysis Open
This retrospective review of 4-year surveillance data revealed a higher central line-associated bloodstream infection (CLABSI) rate in non-Hispanic Black patients and higher catheter-associated urinary tract infection (CAUTI) rates in Asia…
View article: Your Outpatient has Coronavirus Disease 2019: What Are the Treatment Options in the Current Severe Acute Respiratory Syndrome Coronavirus 2 Variant Climate?
Your Outpatient has Coronavirus Disease 2019: What Are the Treatment Options in the Current Severe Acute Respiratory Syndrome Coronavirus 2 Variant Climate? Open
Mutations accumulated by novel Severe Acute Respiratory Syndrome Coronavirus 2 Omicron sublineages contribute to evasion of previously effective monoclonal antibodies for treatment or prevention of Coronavirus Disease 2019 (COVID-19). Othe…
View article: Using clinical decision support to improve urine testing and antibiotic utilization
Using clinical decision support to improve urine testing and antibiotic utilization Open
Objective: Urine cultures collected from catheterized patients have a high likelihood of false-positive results due to colonization. We examined the impact of a clinical decision support (CDS) tool that includes catheter information on tes…