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View article: Novel MAFG-METTL14-SCD1 axis regulates lipid metabolism mediating choroidal melanoma distant metastasis
Novel MAFG-METTL14-SCD1 axis regulates lipid metabolism mediating choroidal melanoma distant metastasis Open
Background Tumor invasion and metastasis are strongly influenced by cell membrane fluidity, regulated by lipid metabolism. In choroidal melanoma (CM), a highly metastatic cancer, the relationship between lipid metabolism, membrane fluidity…
View article: Flexibility Incentive Market Mechanism for Combined Frequency Regulation and Electricity Markets for the Power System with Distributed Energy Resources Aggregators via Modified Leiden Algorithm
Flexibility Incentive Market Mechanism for Combined Frequency Regulation and Electricity Markets for the Power System with Distributed Energy Resources Aggregators via Modified Leiden Algorithm Open
Distributed energy resources provide local power as a supplement on the customer side. Recent rapid development of the distributed energy source enhances the clear energy production at the terminal of the power system. Whereas the small ca…
View article: Multilevel Barriers to Perianal Condyloma Care Among Men Who Have Sex With Men in Northeast China
Multilevel Barriers to Perianal Condyloma Care Among Men Who Have Sex With Men in Northeast China Open
Importance Men who have sex with men (MSM) with perianal condyloma face compounded health care challenges within structural inequities. Current research poorly characterizes their medical experiences, including barriers to care, psychosoci…
View article: Ambient blade-coated perovskite solar cells with high reverse bias stability enabled by polymeric hole transporter design
Ambient blade-coated perovskite solar cells with high reverse bias stability enabled by polymeric hole transporter design Open
Reverse bias stability remains a critical challenge for inverted perovskite solar cells (PSCs). While self-assembled monolayers (SAMs) boost efficiency, their low breakdown voltages limit device reliability. Thick PTAA layer improves break…
View article: Short-term risks of influenza and COVID-19 following influenza infection: A self-controlled case series study
Short-term risks of influenza and COVID-19 following influenza infection: A self-controlled case series study Open
Influenza infection may temporarily increase susceptibility to COVID-19 while reducing the risk of influenza reinfection. These findings highlight the importance of targeted surveillance and preventive strategies during influenza peaks to …
View article: Massive drainage from incision after tunica vaginalis eversion: A case of patent processus vaginalis
Massive drainage from incision after tunica vaginalis eversion: A case of patent processus vaginalis Open
View article: A Nested DUAL-axis Accelerometer with Enhanced Temperature Robustness for Testing Across the Entire Operational Temperature Range
A Nested DUAL-axis Accelerometer with Enhanced Temperature Robustness for Testing Across the Entire Operational Temperature Range Open
This paper investigates a nested biaxial micro-electro-mechanical systems (MEMS) accelerometer with low coupling error, derives the kinetic model equations of the accelerometer, and performs finite element simulations of the operating mode…
View article: Effects of Functional Foods and Dietary Bioactives on Human Health
Effects of Functional Foods and Dietary Bioactives on Human Health Open
Functional foods and dietary bioactives are moving from discovery to translation because we can now engineer structure and exposure together—the two levers that largely determine real-world efficacy [...]
View article: On Accurate and Robust Estimation of 3D and 2D Circular Center: Method and Application to Camera-Lidar Calibration
On Accurate and Robust Estimation of 3D and 2D Circular Center: Method and Application to Camera-Lidar Calibration Open
Circular targets are widely used in LiDAR-camera extrinsic calibration due to their geometric consistency and ease of detection. However, achieving accurate 3D-2D circular center correspondence remains challenging. Existing methods often f…
View article: A Hybrid G-Quadruplex Structure Formed by a Sequence from the MAX Gene
A Hybrid G-Quadruplex Structure Formed by a Sequence from the MAX Gene Open
Here, we report the NMR solution structure of the G-quadruplex (G4) folded by the 24-nt guanine-rich DNA sequence d-[AG3AG4A2G4TGA2G4A]. The sequence is originated from the …
View article: An induced pluripotent stem cell-based chemical genetic approach for studying spinal muscular atrophy
An induced pluripotent stem cell-based chemical genetic approach for studying spinal muscular atrophy Open
Spinal muscular atrophy (SMA) is a genetic disease characterized by degeneration of spinal cord motor neurons and neuromuscular junctions. Despite recent development in therapies for SMA, treatment efficacy largely relies on administration…
View article: A novel long-acting C5a-blocking cyclic peptide prevents sepsis-induced organ dysfunction via effective blockade of the inflammatory cascade
A novel long-acting C5a-blocking cyclic peptide prevents sepsis-induced organ dysfunction via effective blockade of the inflammatory cascade Open
Sepsis is a life-threatening syndrome characterized by dysregulated host responses to infection, leading to severe organ dysfunction and a high mortality rate. Reducing the incidence of sepsis is of paramount importance. Given that sepsis-…
View article: Epidemiological, clinical, and molecular characteristics of coxsackievirus A2 infections during a herpangina outbreak in children on an Island in Eastern China in 2024: a surveillance-based study
Epidemiological, clinical, and molecular characteristics of coxsackievirus A2 infections during a herpangina outbreak in children on an Island in Eastern China in 2024: a surveillance-based study Open
View article: Temporal Evolution and Numerical Simulation of Water-Sensitive Reservoirs During Long-Term Waterflooding: A Case Study of the North 31 Wutonggou Formation
Temporal Evolution and Numerical Simulation of Water-Sensitive Reservoirs During Long-Term Waterflooding: A Case Study of the North 31 Wutonggou Formation Open
This study addresses the challenges of uneven recovery in strongly water-sensitive reservoirs through the development of a time-dependent two-phase flow model capturing the dynamic evolution of permeability and relative permeability. Based…
View article: Aortobronchial Fistula: A Case Report and Literature Review
Aortobronchial Fistula: A Case Report and Literature Review Open
This report details the urgent management of a life‐threatening aortobronchial fistula (ABF) in a 61‐year‐old male with a history of esophageal cancer surgery, who presented with massive hemoptysis, underscoring the critical role of rapid …
View article: Strain-level profiling reveals the impact of prolonged areca nut chewing on oral microbiome
Strain-level profiling reveals the impact of prolonged areca nut chewing on oral microbiome Open
View article: Postoperative kinesiophobia in elderly patients with femoral neck fractures: a prospective study of psychological and social determinants
Postoperative kinesiophobia in elderly patients with femoral neck fractures: a prospective study of psychological and social determinants Open
Objectives This study examined the psychosocial correlates of postoperative kinesiophobia in elderly patients with femoral neck fractures, with a focus on the roles of psychological resilience and social support in mitigating movement-rela…
View article: Correction: Effects of high-definition transcranial direct current stimulation for the treatment of chronic insomnia: a randomized, double-blind, controlled trial
Correction: Effects of high-definition transcranial direct current stimulation for the treatment of chronic insomnia: a randomized, double-blind, controlled trial Open
View article: Cultural Sustainability Through Heritage-Led Underground Development: The Case Study
Cultural Sustainability Through Heritage-Led Underground Development: The Case Study Open
The integration of cultural heritage into sustainable urban development has garnered increasing attention, with a growing recognition of its role in fostering resilient, inclusive, and identity-rich cities. While surface-level monuments of…
View article: Cellular angiofibroma of the inguinal scrotal region: A rare case report
Cellular angiofibroma of the inguinal scrotal region: A rare case report Open
Rationale: Cellular angiofibroma (CAF) is a rare benign mesenchymal tumor, which is difficult to diagnose due to its lack of specificity in clinical and imaging manifestations. This case highlights the challenges in the preoperative diagno…
View article: Cultural Soft Power Empowering Grassroots Political Mobilization
Cultural Soft Power Empowering Grassroots Political Mobilization Open
This paper aims to explore the dual effects of cultural soft power on empowering grassroots political mobilization. In the context of globalization, culture, as a core political resource, plays an increasingly prominent role in consolidati…
View article: A Fast and Lightweight Model for Causal Audio-Visual Speech Separation
A Fast and Lightweight Model for Causal Audio-Visual Speech Separation Open
Audio-visual speech separation (AVSS) aims to extract a target speech signal from a mixed signal by leveraging both auditory and visual (lip movement) cues. However, most existing AVSS methods exhibit complex architectures and rely on futu…
View article: Blood pressure levels and risk of intracerebral hemorrhage in the general population: evidence from a large prospective cohort study
Blood pressure levels and risk of intracerebral hemorrhage in the general population: evidence from a large prospective cohort study Open
In this large cohort of adults without baseline stroke and coronary heart disease, moderately lower BP levels were associated with reduced risk of incident ICH. These findings may help refine our understanding of BP thresholds relevant to …
View article: Unraveling the multidimensional association of covert bullying, abandonment, and adolescent depression: A critical review and conceptual framework
Unraveling the multidimensional association of covert bullying, abandonment, and adolescent depression: A critical review and conceptual framework Open
This critical review examines the complex relationships between covert bullying, feelings of abandonment, and adolescent depression through an integrative analysis of contemporary literature. By synthesizing evidence from empirical studies…
View article: Photodoping strategies in two‐dimensional semiconductors: Mechanisms, characterizations, and emerging applications
Photodoping strategies in two‐dimensional semiconductors: Mechanisms, characterizations, and emerging applications Open
The rapid expansion of two‐dimensional (2D) van der Waals semiconductors has enabled new possibilities for next‐generation electronic and optoelectronic technologies. However, the absence of robust, scalable, and CMOS‐compatible doping str…
View article: Current status and influencing factors of decision-making readiness among lung cancer patients during chemotherapy: a cross-sectional study based on CSM model
Current status and influencing factors of decision-making readiness among lung cancer patients during chemotherapy: a cross-sectional study based on CSM model Open
Objective This study aimed to investigate the current status of decision - making readiness (DMR) among lung cancer patients during chemotherapy and to explore its influencing factors, with the goal of informing targeted clinical intervent…
View article: Screening and verification of EmMYB5 in flavonoids biosynthesis in Elaeagnus mollis dies kernel
Screening and verification of EmMYB5 in flavonoids biosynthesis in Elaeagnus mollis dies kernel Open
Flavonoids are natural bioactive compounds with demonstrated health benefits in humans. Elaeagnus mollis Diels is a novel developing woody oil crop, and the flavonoids in E. mollis have attracted more attention. However, the composition co…
View article: APPLICATION OF <italic>BACILLUS SUBTILIS</italic> TO IMPROVE GROWTH, IMMUNITY, AND RESISTANCE TO <italic>VIBRIO PARAHAEMOLYTICUS</italic> INFECTION IN <italic>LITOPENAEUS VANNAMEI</italic>
APPLICATION OF <italic>BACILLUS SUBTILIS</italic> TO IMPROVE GROWTH, IMMUNITY, AND RESISTANCE TO <italic>VIBRIO PARAHAEMOLYTICUS</italic> INFECTION IN <italic>LITOPENAEUS VANNAMEI</italic> Open
View article: Atomic‐Level Dual‐Cation Engineering Enables High‐Performance Na<sub>4</sub>VMn(PO<sub>4</sub>)<sub>3</sub> Cathodes for Sodium‐Ion Batteries
Atomic‐Level Dual‐Cation Engineering Enables High‐Performance Na<sub>4</sub>VMn(PO<sub>4</sub>)<sub>3</sub> Cathodes for Sodium‐Ion Batteries Open
Na Super Ionic Conductor (NASICON)‐type Na 4 VMn(PO 4 ) 3 (NVMP) is a promising cathode for sodium‐ion batteries (SIBs) but suffers from sluggish Na‐ion transport and capacity fading. Here, we propose a site‐selective dual‐cation engineeri…
View article: Extrapulmonary metastases impact survival outcomes of thermal ablation for colorectal lung oligometastases: A multicenter study
Extrapulmonary metastases impact survival outcomes of thermal ablation for colorectal lung oligometastases: A multicenter study Open
BACKGROUND Colorectal cancer (CRC) frequently metastasizes to the lungs, and image-guided thermal ablation (IGTA) has emerged as a promising treatment for oligometastatic colorectal lung metastases (CRLM). However, high-quality multicenter…