Songjie Liao
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View article: Corticospinal tract involvement in Spinocerebellar ataxias type 1, 2 and 3 characterized by motor evoked potential and diffusion MRI
Corticospinal tract involvement in Spinocerebellar ataxias type 1, 2 and 3 characterized by motor evoked potential and diffusion MRI Open
Background Spinocerebellar ataxia (SCA) type 1, 2, and 3 are the most frequent spinocerebellar ataxia, characterized by brainstem, basal ganglia and cerebellar damage. To date, no studies have investigated damage in the corticospinal tract…
View article: Rare Giant Cardiac Malignancy: Primary Cardiac Synovial Sarcoma
Rare Giant Cardiac Malignancy: Primary Cardiac Synovial Sarcoma Open
We present a case of a primary cardiac synovial sarcoma, surrounding the right coronary artery and leaded to accelerate the blood flow of the tricuspid valve orifice.
View article: LncRNA TUG1 contributes post-stroke NLRP3 inflammasome-dependent pyroptosis via miR-145a-5p/TLR4 axis
LncRNA TUG1 contributes post-stroke NLRP3 inflammasome-dependent pyroptosis via miR-145a-5p/TLR4 axis Open
Objective: Pyroptosis, a type of programmed cell death illuminated by inflammasomes and active caspases, is implicated in post-stroke inflammation. Our previous study showed that lncRNA taurine up-regulated gene 1 (TUG1) sponging miR-145a-…
View article: Anti-GQ1b Antibody Syndrome with Visual Impairment: A Retrospective Case Series
Anti-GQ1b Antibody Syndrome with Visual Impairment: A Retrospective Case Series Open
Background: Anti-GQ1b antibody syndrome referred to a clinical spectrum characterized by acute onset of ataxia, ophthalmoplegia and areflexia, while visual deterioration was rarely reported in terms of ocular disorders. This study aimed to…
View article: The Physiological Significance of A-Waves in Early Diabetic Neuropathy: Assessment of Motor Nerve Fibers by Neurophysiological Techniques
The Physiological Significance of A-Waves in Early Diabetic Neuropathy: Assessment of Motor Nerve Fibers by Neurophysiological Techniques Open
Objective: This study aimed to investigate how early A-waves could occur in type II diabetes, and what it implied functionally. Methods: We performed conduction velocity distribution (CVD) test in peroneal nerves of 37 type II diabetic pat…
View article: Stiff-person syndrome coexisting with critical illness polyneuropathy
Stiff-person syndrome coexisting with critical illness polyneuropathy Open
Rationale: Stiff-person syndrome (SPS) is an uncommon neurological disorder with autoimmune features. Here, we report a 60-year-old man with SPS associated with critical illness polyneuropathy (CIP). CIP was diagnosed during an episode of …
View article: Comparison of Novel Oral Anticoagulants and Vitamin K Antagonists in Patients With Cerebral Venous Sinus Thrombosis on Efficacy and Safety: A Systematic Review
Comparison of Novel Oral Anticoagulants and Vitamin K Antagonists in Patients With Cerebral Venous Sinus Thrombosis on Efficacy and Safety: A Systematic Review Open
Vitamin K antagonists (VKAs) are guideline-suggested subacute anticoagulants for cerebral venous sinus thrombosis (CVST), although there is potential hemorrhage risk in clinical use. In the last decade, novel oral anticoagulants (NOACs) ha…
View article: Author response for "Local uncoordinated gene 5H2 contributes to nerve injury‐induced mechanical allodynia associated to its role in autophagy"
Author response for "Local uncoordinated gene 5H2 contributes to nerve injury‐induced mechanical allodynia associated to its role in autophagy" Open
View article: Clinical and Physiological Significance of F-Wave in Spinocerebellar Ataxia Type 3
Clinical and Physiological Significance of F-Wave in Spinocerebellar Ataxia Type 3 Open
Objective: To evaluate the characteristics of F-wave in spinocerebellar ataxia type 3 (SCA3) patients and preclinical carriers of SCA3 gene mutation (PreSCA3), and explore the relationship between disease severity and F-wave paramet…
View article: Muscular involvement and tendon contracture in limb-girdle muscular dystrophy 2Y: a mild adult phenotype and literature review
Muscular involvement and tendon contracture in limb-girdle muscular dystrophy 2Y: a mild adult phenotype and literature review Open
Background Limb girdle muscular dystrophy type 2Y (LGMD2Y) is a rare subgroup of limb girdle muscular dystrophy featuring limb-girdle weakness, tendon contracture and cardiac involvement. It is caused by the mutation of TOR1AIP1, which enc…
View article: The rostral to caudal gradient of clinical and electrophysiological features in sporadic amyotrophic lateral sclerosis with bulbar-onset
The rostral to caudal gradient of clinical and electrophysiological features in sporadic amyotrophic lateral sclerosis with bulbar-onset Open
Objective Amyotrophic lateral sclerosis (ALS) with bulbar-onset (BO-ALS) tends to propagate to the adjacent anatomical regions symptomatically. However, the spreading pattern of clinical and electrophysiological features is not well docume…
View article: Klippel–Trenaunay and Sturge–Weber Overlap Syndrome with KRAS and GNAQ mutations
Klippel–Trenaunay and Sturge–Weber Overlap Syndrome with KRAS and GNAQ mutations Open
Patients with combined phenotypes of Sturge–Weber syndrome and Klippel–Trenaunay syndrome have been reported, though the underlying genetic spectrum in these individuals remains to be elucidated. We reported the patient presenting with Kli…
View article: Long Non-coding RNA TUG1 Sponges Mir-145a-5p to Regulate Microglial Polarization After Oxygen-Glucose Deprivation
Long Non-coding RNA TUG1 Sponges Mir-145a-5p to Regulate Microglial Polarization After Oxygen-Glucose Deprivation Open
Microglia plays a critical role in neuroinflammation after ischemic stroke by releasing diverse inflammatory cytokines. Long non-coding RNA taurine up-regulated gene 1 (lncRNA TUG1) is widely expressed in adult brain and has been reported …
View article: Netrin-1 Ameliorates Blood-Brain Barrier Impairment Secondary to Ischemic Stroke via the Activation of PI3K Pathway
Netrin-1 Ameliorates Blood-Brain Barrier Impairment Secondary to Ischemic Stroke via the Activation of PI3K Pathway Open
Secondary impairment of blood-brain barrier (BBB) occurs in the remote thalamus after ischemic stroke. Netrin-1, an axonal guidance molecule, presents bifunctional effects on blood vessels through receptor-dependent pathways. This study in…
View article: The relationship between exposure to hepatitis B virus and increased atherosclerosis-associated morbidity — a meta-analysis
The relationship between exposure to hepatitis B virus and increased atherosclerosis-associated morbidity — a meta-analysis Open
Hepatitis B virus may not be a risk factor for atherosclerosis-associated diseases, but further studies that employ more sensitive clinical parameters are needed to verify this result.
View article: Tuberous Sclerosis Complex Confirmed by Genetic Analysis: A Case Report
Tuberous Sclerosis Complex Confirmed by Genetic Analysis: A Case Report Open
Tuberous sclerosis complex (TSC), also known as Bourneville disease, is an autosomal-dominant, neurocutaneous, multisystem disorder [1]. The underlying genetic cause is mutations in the TSC1 or TSC2 gene, which leads to overactivation of t…