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View article: Hierarchical materials as tissue-like phantoms for photoacoustic imaging
Hierarchical materials as tissue-like phantoms for photoacoustic imaging Open
We introduce a hierarchical manufacturing method for creating anatomical phantoms using water-in-elastomer micro-emulsions. This approach addresses the cost, ethical, and technical limitations of animal models, providing a reliable alterna…
View article: Sponges Based on Polydimethylsiloxane as Pulmonary Phantoms for Diffuse Optics
Sponges Based on Polydimethylsiloxane as Pulmonary Phantoms for Diffuse Optics Open
Diagnostic testing is evolving towards multimodal and hybrid approaches, which require accurate and dynamic phantoms for objective performance assessment. In particular, pulmonary phantoms, critical for evaluating deep penetration optical …
View article: Photomobile Polymer–Piezoelectric Composite for Enhanced Actuation and Energy Generation
Photomobile Polymer–Piezoelectric Composite for Enhanced Actuation and Energy Generation Open
In this study, we present an innovative approach to increase the quantum yield and wavelength sensitivity of photomobile polymer (PMP) films based on azobenzene by doping the polymer matrix with noble metal nanoparticles. These doped PMP f…
View article: Thermometric absorption spectroscopy through active locking of microbubble resonators
Thermometric absorption spectroscopy through active locking of microbubble resonators Open
We implemented a Microbubble Resonator (MBRs) as an opto-thermal transducer to reconstruct the absorption spectrum of a nanoparticle suspension through its temperature increase. The experimental configuration features the MBR as both the v…
View article: Paper-based genetic assays with bioconjugated gold nanorods and an automated readout pipeline
Paper-based genetic assays with bioconjugated gold nanorods and an automated readout pipeline Open
Paper-based biosensors featuring immunoconjugated gold nanoparticles have gained extraordinary momentum in recent times as the platform of choice in key cases of field applications, including the so-called rapid antigen tests for SARS-CoV-…
View article: Paper-based genetic assays with bioconjugated gold nanorods and an automated readout pipeline
Paper-based genetic assays with bioconjugated gold nanorods and an automated readout pipeline Open
BackgroundPaper-based biosensors featuring immunoconjugated gold nanoparticles have gained extraordinary momentum in recent times as the platform of choice in key cases of field applications, including the so-called rapid antigen tests for…
View article: Microbubble resonators for scattering-free absorption spectroscopy of nanoparticles
Microbubble resonators for scattering-free absorption spectroscopy of nanoparticles Open
We present a proof-of-concept experiment where the absorbance spectra of suspensions of plasmonic nanoparticles are accurately reconstructed through the photothermal conversion that they mediate in a microbubble resonator. This thermal det…
View article: Theranostic Nanoparticles: Enhanced Antitumoral Activity and Photoacoustic Imaging Properties of AuNP‐Enriched Endothelial Colony Forming Cells on Melanoma (Adv. Sci. 4/2021)
Theranostic Nanoparticles: Enhanced Antitumoral Activity and Photoacoustic Imaging Properties of AuNP‐Enriched Endothelial Colony Forming Cells on Melanoma (Adv. Sci. 4/2021) Open
In article number 2001175, Paolo Armanetti and co‐workers demonstrate the tumor‐homing efficiency and antitumoral activity of Au nanoparticles‐loaded Endothelial Colony Forming Cells (ECFCs). The image represents a cell loaded with AuNPs w…
View article: Photostability of Contrast Agents for Photoacoustics: The Case of Gold Nanorods
Photostability of Contrast Agents for Photoacoustics: The Case of Gold Nanorods Open
Plasmonic particles as gold nanorods have emerged as powerful contrast agents for critical applications as the photoacoustic imaging and photothermal ablation of cancer. However, their unique efficiency of photothermal conversion may turn …
View article: Enhanced Antitumoral Activity and Photoacoustic Imaging Properties of AuNP‐Enriched Endothelial Colony Forming Cells on Melanoma
Enhanced Antitumoral Activity and Photoacoustic Imaging Properties of AuNP‐Enriched Endothelial Colony Forming Cells on Melanoma Open
Near infrared (NIR)‐resonant gold nanoparticles (AuNPs) hold great promise in cancer diagnostics and treatment. However, translating the theranostic potential of AuNPs into clinical applications still remains a challenge due to the difficu…
View article: Inside Cover
Inside Cover Open
Cross‐polarised optical coherence tomography is a promising technique to reveal certain pathologic conditions in tissue. However, endoscopic devices with flexible small probes to detect diseased areas intraoperatively barely exist. We pres…
View article: Small Thiols Stabilize the Shape of Gold Nanorods
Small Thiols Stabilize the Shape of Gold Nanorods Open
The stabilization of the optical properties of anisotropic plasmonic particles upon thermal annealing and laser irradiation is an important issue in many biomedical applications. Here, we address the effect of small thiols on the thermal a…
View article: Microbubble Resonators for All-Optical Photoacoustics of Flowing Contrast Agents
Microbubble Resonators for All-Optical Photoacoustics of Flowing Contrast Agents Open
In this paper, we implement a Whispering Gallery mode microbubble resonator (MBR) as an optical transducer to detect the photoacoustic (PA) signal generated by plasmonic nanoparticles. We simulate a flow cytometry experiment by letting the…
View article: Hybrid organosilicon/polyol phantom for photoacoustic imaging
Hybrid organosilicon/polyol phantom for photoacoustic imaging Open
The rapid development of hardware and software for photoacoustic technologies is urging the establishment of dedicated tools for standardization and performance assessment. In particular, the fabrication of anatomical phantoms for photoaco…
View article: A Robust Design for Cellular Vehicles of Gold Nanorods for Multimodal Imaging
A Robust Design for Cellular Vehicles of Gold Nanorods for Multimodal Imaging Open
Authors Dr. Marisa Benagiano and Prof. Mario Milco D’Elios were not included when this article was originally published. The corrected list of author of this manuscript is: F. Ratto,* S. Centi, C. Avigo, C. Borri, F. Tatini, L. Cavigli, C.…
View article: A Robust Design for Cellular Vehicles of Gold Nanorods for Multimodal Imaging
A Robust Design for Cellular Vehicles of Gold Nanorods for Multimodal Imaging Open
The pursuit of more selectivity in the delivery of plasmonic particles to tumors is critical before their penetration into clinical applications as the photoacoustic imaging and the photothermal ablation of cancer. As their direct infusion…
View article: Preparation and Photoacoustic Analysis of Cellular Vehicles Containing Gold Nanorods
Preparation and Photoacoustic Analysis of Cellular Vehicles Containing Gold Nanorods Open
Gold nanorods are attractive for a range of biomedical applications, such as the photothermal ablation and the photoacoustic imaging of cancer, thanks to their intense optical absorbance in the near-infrared window, low cytotoxicity and po…