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View article: Estimating probabilities of malaria importation in southern Mozambique through P. falciparum genomics and mobility patterns
Estimating probabilities of malaria importation in southern Mozambique through P. falciparum genomics and mobility patterns Open
Imported malaria is a critical obstacle to achieving elimination in low transmission settings. Characterising malaria importation and transmission sources using human mobility and parasite genomics has the potential to inform elimination s…
View article: Estimating probabilities of malaria importation in southern Mozambique through P. falciparum genomics and mobility patterns
Estimating probabilities of malaria importation in southern Mozambique through P. falciparum genomics and mobility patterns Open
Imported malaria is a critical obstacle to achieving elimination in low transmission settings. Characterising malaria importation and transmission sources using human mobility and parasite genomics has the potential to inform elimination s…
View article: Hybrid Immunity in a Mozambican Cohort After 1 or 2 Doses of the BBIBP-CorV Vaccine
Hybrid Immunity in a Mozambican Cohort After 1 or 2 Doses of the BBIBP-CorV Vaccine Open
Background More than half of the BBIBP-CorV vaccines, outside of Pacific Asia, were distributed in Africa. Nevertheless, there are limited data on the immunogenicity of BBIBP-CorV from Africa. We compared the antibody response, after 1 and…
View article: Estimating probabilities of malaria importation in southern Mozambique through <i>P. falciparum</i> genomics and mobility patterns
Estimating probabilities of malaria importation in southern Mozambique through <i>P. falciparum</i> genomics and mobility patterns Open
Imported malaria is a critical obstacle to achieving elimination in low transmission settings. Characterising malaria importation and transmission sources using human mobility and parasite genomics has the potential to inform elimination s…
View article: High SARS‐CoV‐2 Exposure in Rural Southern Mozambique After Four Waves of COVID‐19: Community‐Based Seroepidemiological Surveys
High SARS‐CoV‐2 Exposure in Rural Southern Mozambique After Four Waves of COVID‐19: Community‐Based Seroepidemiological Surveys Open
Background Mozambique was one of many African countries with limited testing capacity for SARS‐CoV‐2. Serosurveys, an alternative to estimate the real exposure to understand the epidemiology and transmission dynamics, have been scarce in M…
View article: Results from phase one of a hybrid effectiveness-implementation study to assess the feasibility, acceptability and effectiveness of implementing seasonal malaria chemoprevention in Nampula province, Mozambique
Results from phase one of a hybrid effectiveness-implementation study to assess the feasibility, acceptability and effectiveness of implementing seasonal malaria chemoprevention in Nampula province, Mozambique Open
Introduction Seasonal malaria chemoprevention (SMC) is a highly effective intervention for malaria prevention in high burden areas with seasonal transmission, historically implemented in the Sahel. Mozambique contributes to 4% of global ma…
View article: Targeted and whole-genome sequencing reveal a north-south divide in P. falciparum drug resistance markers and genetic structure in Mozambique
Targeted and whole-genome sequencing reveal a north-south divide in P. falciparum drug resistance markers and genetic structure in Mozambique Open
Mozambique is one of the four African countries which account for over half of all malaria deaths worldwide, yet little is known about the parasite genetic structure in that country. We performed P. falciparum amplicon and whole genome seq…
View article: Prevalence of and risk factors for microscopic and submicroscopic malaria infections in pregnancy: a systematic review and meta-analysis
Prevalence of and risk factors for microscopic and submicroscopic malaria infections in pregnancy: a systematic review and meta-analysis Open
Bill & Melinda Gates Foundation through the Worldwide Antimalarial Resistance Network.
View article: Tracking SARS-CoV-2 introductions in Mozambique using pandemic-scale phylogenies: a retrospective observational study
Tracking SARS-CoV-2 introductions in Mozambique using pandemic-scale phylogenies: a retrospective observational study Open
European and Developing Countries Clinical Trials, European Research Council, Bill & Melinda Gates Foundation, and Agència de Gestió d'Ajuts Universitaris i de Recerca.
View article: Antimalarial resistance in Mozambique: Absence of Plasmodium falciparum Kelch 13 (K13) propeller domain polymorphisms associated with resistance to artemisinins
Antimalarial resistance in Mozambique: Absence of Plasmodium falciparum Kelch 13 (K13) propeller domain polymorphisms associated with resistance to artemisinins Open
Malaria remains one of the most serious public health problem in sub-Saharan Africa and Mozambique is the world's fourth largest contributor, with 4.7% of disease cases and 3.6% of total deaths due to malaria. Its control relies on the fig…
View article: Feasibility, Acceptability, and Protective Efficacy of Seasonal Malaria Chemoprevention Implementation in Nampula Province, Mozambique: Protocol for a Hybrid Effectiveness-Implementation Study
Feasibility, Acceptability, and Protective Efficacy of Seasonal Malaria Chemoprevention Implementation in Nampula Province, Mozambique: Protocol for a Hybrid Effectiveness-Implementation Study Open
Background Seasonal malaria chemoprevention (SMC) is a highly effective community-based intervention to prevent malaria infections in areas where the malaria burden is high and transmission occurs mainly during the rainy season. In Africa,…
View article: Prospective surveillance study to detect antimalarial drug resistance, gene deletions of diagnostic relevance and genetic diversity of <i>Plasmodium falciparum</i> in Mozambique: protocol
Prospective surveillance study to detect antimalarial drug resistance, gene deletions of diagnostic relevance and genetic diversity of <i>Plasmodium falciparum</i> in Mozambique: protocol Open
Introduction Genomic data constitute a valuable adjunct to routine surveillance that can guide programmatic decisions to reduce the burden of infectious diseases. However, genomic capacities remain low in Africa. This study aims to operati…
View article: A protocol for a hybrid effectiveness-implementation study to assess the feasibility, acceptability and protective efficacy of implementing seasonal malaria chemoprevention in Nampula province, Mozambique (Preprint)
A protocol for a hybrid effectiveness-implementation study to assess the feasibility, acceptability and protective efficacy of implementing seasonal malaria chemoprevention in Nampula province, Mozambique (Preprint) Open
BACKGROUND Seasonal malaria chemoprevention (SMC) is a highly effective community-based intervention to prevent malaria infections in areas where the malaria burden is high and transmission occurs mainly during the rainy season. In Africa…
View article: In vivo efficacy and safety of artemether–lumefantrine and amodiaquine–artesunate for uncomplicated Plasmodium falciparum malaria in Mozambique, 2018
In vivo efficacy and safety of artemether–lumefantrine and amodiaquine–artesunate for uncomplicated Plasmodium falciparum malaria in Mozambique, 2018 Open
Background Artemisinin-based combination therapy (ACT) has been the recommended first-line treatment for uncomplicated malaria in Mozambique since 2006, with artemether–lumefantrine (AL) and amodiaquine–artesunate (AS–AQ) as the first choi…
View article: In vivo Efficacy and Safety of Artemether-Lumefantrine and Amodiaquine-Artesunate for Uncomplicated Plasmodium Falciparum Malaria in Mozambique, 2018
In vivo Efficacy and Safety of Artemether-Lumefantrine and Amodiaquine-Artesunate for Uncomplicated Plasmodium Falciparum Malaria in Mozambique, 2018 Open
Background : Artemisinin-based combination therapy has been the recommended treatment for uncomplicated malaria in Mozambique since 2006, with artemether-lumefantrine (AL) and amodiaquine-artesunate (AS-AQ) as first-line treatments. To ass…
View article: Assessment of the Feasibility, Acceptability, and Impact of Implementing Seasonal Malaria Chemoprevention in Nampula Province, Mozambique: Protocol for a Hybrid Effectiveness-Implementation Study
Assessment of the Feasibility, Acceptability, and Impact of Implementing Seasonal Malaria Chemoprevention in Nampula Province, Mozambique: Protocol for a Hybrid Effectiveness-Implementation Study Open
Background Malaria is a significant cause of morbidity and mortality in children aged under 5 years in Mozambique. The World Health Organization recommends seasonal malaria chemoprevention (SMC), the administration of four monthly courses …
View article: Assessment of the Feasibility, Acceptability, and Impact of Implementing Seasonal Malaria Chemoprevention in Nampula Province, Mozambique: Protocol for a Hybrid Effectiveness-Implementation Study (Preprint)
Assessment of the Feasibility, Acceptability, and Impact of Implementing Seasonal Malaria Chemoprevention in Nampula Province, Mozambique: Protocol for a Hybrid Effectiveness-Implementation Study (Preprint) Open
BACKGROUND Malaria is a significant cause of morbidity and mortality in children aged under 5 years in Mozambique. The World Health Organization recommends seasonal malaria chemoprevention (SMC), the administration of four monthly courses…
View article: Factors Associated with Prevalence of Malaria Infection among Children under 5 Years of Age in Mozambique: 2015 vs 2018
Factors Associated with Prevalence of Malaria Infection among Children under 5 Years of Age in Mozambique: 2015 vs 2018 Open
Background: Malaria is still a leading cause of morbidity and mortality among children under five years old in Mozambique. In this study we sought to determine the prevalence of malaria infection and its predictors among children six to 59…
View article: Adherence to COVID-19 Preventive Measures in Mozambique: Two Consecutive Online Surveys
Adherence to COVID-19 Preventive Measures in Mozambique: Two Consecutive Online Surveys Open
We assessed adherence to government recommendations implemented shortly after the introduction of COVID-19 in Mozambique in March 2020, through two online cross-sectional surveys in April and June 2020. We quantified adherence to preventiv…
View article: Additional file 1 of In vivo efficacy and safety of artemether–lumefantrine and amodiaquine–artesunate for uncomplicated Plasmodium falciparum malaria in Mozambique, 2018
Additional file 1 of In vivo efficacy and safety of artemether–lumefantrine and amodiaquine–artesunate for uncomplicated Plasmodium falciparum malaria in Mozambique, 2018 Open
Additional file 1: Table S1. Observed fragment lengths of neutral microsatellite loci from paired Day 0 (D0) and Day of Failure samples (D7, D14, D21, etc.) from a therapeutic efficacy study in Mozambique, 2018.
View article: HIV Prevalence and Incidence in a Cohort of Women at Higher Risk for HIV Acquisition in Chókwè, Southern Mozambique
HIV Prevalence and Incidence in a Cohort of Women at Higher Risk for HIV Acquisition in Chókwè, Southern Mozambique Open
BackgroundReliable HIV incidence estimates for Mozambique are limited. We conducted a prospective HIV incidence study as part of a clinical research site development initiative in Chókwè district, Gaza Province, southern Mozambique.Methods…
View article: Access to and use of preventive intermittent treatment for Malaria during pregnancy: A qualitative study in the Chókwè district, Southern Mozambique
Access to and use of preventive intermittent treatment for Malaria during pregnancy: A qualitative study in the Chókwè district, Southern Mozambique Open
Pregnant women face substantial barriers in terms of optimal IPTp-SP uptake. Health system barriers and poor awareness of the risks and consequences of MiP and of the measures available for its prevention were identified as the main factor…