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View article: Integration of mesenchymal stem cells into islet cell spheroids improves long-term viability, but not islet function
Integration of mesenchymal stem cells into islet cell spheroids improves long-term viability, but not islet function Open
Pancreatic islets, especially the large islets (> 150µm in diameter) have poor survival rates in culture. Co-culturing with mesenchymal stem cells (MSCs) has been shown to improve islet survival and function. However, most co-culture studi…
View article: Hyaluronic Acid/Collagen Hydrogel as an Alternative to Alginate for Long-Term Immunoprotected Islet Transplantation <sup/>
Hyaluronic Acid/Collagen Hydrogel as an Alternative to Alginate for Long-Term Immunoprotected Islet Transplantation <sup/> Open
Alginate has long been the material of choice for immunoprotection of islets due to its low cost and ability to easily form microspheres. Unfortunately, this seaweed-derived material is notoriously prone to fibrotic overgrowth in vivo, res…
View article: REAGGREGATION OF PANCREATIC ISLET CELLS: IMPLICATIONS FOR ISLET HEALTH, STORAGE AND NEW DRUG DISCOVERY
REAGGREGATION OF PANCREATIC ISLET CELLS: IMPLICATIONS FOR ISLET HEALTH, STORAGE AND NEW DRUG DISCOVERY Open
Islets are clusters of cells in the pancreas that monitor and regulate blood glucose levels. In culture, single islet cells reaggregate into clusters, but the reaggregation process is random, resulting in large variation in the cluster num…