Sonja Gröschel
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View article: Mortality within three months after nonfatal ischemic stroke treated by mechanical thrombectomy in routine care—data from the German Stroke Registry
Mortality within three months after nonfatal ischemic stroke treated by mechanical thrombectomy in routine care—data from the German Stroke Registry Open
Background Mechanical thrombectomy (MT) is a highly effective treatment for large vessel occlusion (LVO) ischemic stroke. However, a substantial share of patients have lethal outcome within 3 months. Individualization of outcome prognostic…
View article: Baseline characteristics of patients with acute ischaemic stroke included in the randomised controlled Find-AF 2 trial
Baseline characteristics of patients with acute ischaemic stroke included in the randomised controlled Find-AF 2 trial Open
Background In the Find-AF 2 randomised controlled trial, we investigate whether a risk-adapted intensified heart rhythm monitoring with subsequent initiation of oral anticoagulation in ischaemic stroke patients leads to a reduction of recu…
View article: Do scoring systems help us to estimate prognosis after mechanical thrombectomy? Data from the German Stroke Registry
Do scoring systems help us to estimate prognosis after mechanical thrombectomy? Data from the German Stroke Registry Open
Background Numerous scoring systems have been developed to individualize estimation of functional outcome after endovascular thrombectomy (EVT) of acute ischemic stroke. The aim of our study was to assess their utility for clinical practic…
View article: Delirium following mechanical thrombectomy for ischemic stroke – individuals at risk, imaging biomarkers and prognosis
Delirium following mechanical thrombectomy for ischemic stroke – individuals at risk, imaging biomarkers and prognosis Open
Aim Post-stroke-delirium has been linked to worse outcome in patients with acute cerebrovascular disease; identification of individuals at risk may prevent delirium and thereby improve outcome. We investigate prognosis and factors associat…
View article: Association of oral anticoagulants with risk of brain haemorrhage expansion compared to no-anticoagulation
Association of oral anticoagulants with risk of brain haemorrhage expansion compared to no-anticoagulation Open
Background The impact of direct oral anticoagulants (DOAC) on haematoma size after intracerebral haemorrhage (ICH) compared to no-anticoagulation is controversial and prospective data are lacking. Methods The investigator-initiated, multic…
View article: DSA-based perfusion parameters versus TICI score after mechanical thrombectomy in acute ischaemic stroke patients: a congruence analysis
DSA-based perfusion parameters versus TICI score after mechanical thrombectomy in acute ischaemic stroke patients: a congruence analysis Open
Background Several factors are frequently considered for outcome prediction rin stroke patients. We assessed the value of digital subtraction angiography (DSA)-based brain perfusion measurements after mechanical thrombectomy (MT) for outco…
View article: Neurologischer Notfall nach dentaler Implantation – was nun?
Neurologischer Notfall nach dentaler Implantation – was nun? Open
The following case report presents a 37-year old male patient who was referred for an emergency assessment due to suspected neurovascular damage of the inferior alveolar nerve following placement of two implants in the posterior left mandi…
View article: Strict blood pressure control following thrombectomy is associated with neuronal injury and poor functional outcome
Strict blood pressure control following thrombectomy is associated with neuronal injury and poor functional outcome Open
Objective Mechanical thrombectomy (MT) has become standard treatment in acute ischemic stroke due to large vessel occlusion (LVO). However, optimal blood pressure (BP) management following successful recanalization remains unclear. We aim …
View article: Real world data in mechanical thrombectomy: who are we losing to follow-up?
Real world data in mechanical thrombectomy: who are we losing to follow-up? Open
Background Missing outcome data (MOD) is a common problem in clinical trials and registries, and a potential bias when drawing conclusions from these data. Identifying factors associated with MOD may help to increase follow-up rates and as…
View article: Intensive heart rhythm monitoring to decrease ischemic stroke and systemic embolism—the Find-AF 2 study—rationale and design
Intensive heart rhythm monitoring to decrease ischemic stroke and systemic embolism—the Find-AF 2 study—rationale and design Open
The Find-AF 2 trial aims to demonstrate that enhanced, prolonged and intensified rhythm monitoring results in a more effective prevention of recurrent ischemic stroke and systemic embolism compared to usual care.
View article: Association of Delirium Incidence with Visitation Restrictions due to COVID-19 Pandemic in Patients with Acute Cerebrovascular Disease in a Stroke-Unit Setting: A Retrospective Cohort Study
Association of Delirium Incidence with Visitation Restrictions due to COVID-19 Pandemic in Patients with Acute Cerebrovascular Disease in a Stroke-Unit Setting: A Retrospective Cohort Study Open
Introduction: Hospitals around the world introduced considerable visitation restrictions to reduce risk of infection during epidemic spread of SARS-CoV2. Understanding of negative impacts of visitation restrictions on subgroups of patients…
View article: Sex Disparities in Re-Employment in Stroke Patients With Large Vessel Occlusion Undergoing Mechanical Thrombectomy
Sex Disparities in Re-Employment in Stroke Patients With Large Vessel Occlusion Undergoing Mechanical Thrombectomy Open
Background: Strokes in the working-age population represent a relevant share of ischemic strokes and re-employment is a major factor for well-being in these patients. Income differences by sex have been suspected a barrier for women in ret…
View article: The Bigger the Better? Center Volume Dependent Effects on Procedural and Functional Outcome in Established Endovascular Stroke Centers
The Bigger the Better? Center Volume Dependent Effects on Procedural and Functional Outcome in Established Endovascular Stroke Centers Open
Background Mechanical thrombectomy (MT) rates for the treatment of acute ischaemic stroke due to large vessel occlusion are steadily increasing, but are delivered in heterogenic settings. We aim to investigate effects of procedural load in…
View article: Long-Term Follow-up of Enhanced Holter-Electrocardiography Monitoring in Acute Ischemic Stroke
Long-Term Follow-up of Enhanced Holter-Electrocardiography Monitoring in Acute Ischemic Stroke Open
Background and Purpose Prolonged electrocardiography (ECG)-monitoring in stroke patients improves the detection of paroxysmal atrial fibrillation (pAF). However, most randomized studies only had short follow-up. We aimed to provide 3-year …
View article: Evaluation of coercive measures in different psychiatric hospitals: the impact of institutional characteristics
Evaluation of coercive measures in different psychiatric hospitals: the impact of institutional characteristics Open
View article: Health-related quality of life, anxiety and depression up to 12 months post-stroke: Influence of sex, age, stroke severity and atrial fibrillation – A longitudinal subanalysis of the Find-AFRANDOMISED trial
Health-related quality of life, anxiety and depression up to 12 months post-stroke: Influence of sex, age, stroke severity and atrial fibrillation – A longitudinal subanalysis of the Find-AFRANDOMISED trial Open
Clinical Trial Registration-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01855035.
View article: Stroke Care Within the COVID-19 Pandemic—Increasing Awareness of Transient and Mild Stroke Symptoms Needed
Stroke Care Within the COVID-19 Pandemic—Increasing Awareness of Transient and Mild Stroke Symptoms Needed Open
Background: The COVID-19 pandemic might affect health care resources and alter patient admission to hospital in case of stroke or transient ischemic attack (TIA). We aim to determine whether the COVID-19 pandemic is affecting utiliz…
View article: Software‐based analysis of 1‐hour Holter ECG to select for prolonged ECG monitoring after stroke
Software‐based analysis of 1‐hour Holter ECG to select for prolonged ECG monitoring after stroke Open
Objective Identification of ischemic stroke patients at high risk for paroxysmal atrial fibrillation (pAF) during 72 hours Holter ECG might be useful to individualize the allocation of prolonged ECG monitoring times, currently not routinel…
View article: Automatic Holter electrocardiogram analysis in ischaemic stroke patients to detect paroxysmal atrial fibrillation: ready to replace physicians?
Automatic Holter electrocardiogram analysis in ischaemic stroke patients to detect paroxysmal atrial fibrillation: ready to replace physicians? Open
Background and purpose The detection of paroxysmal atrial fibrillation (pAF) in patients presenting with ischaemic stroke shifts secondary stroke prevention to oral anticoagulation. In order to deal with the time‐ and resource‐consuming ma…
View article: Brain Natriuretic Peptide and Discovery of Atrial Fibrillation After Stroke
Brain Natriuretic Peptide and Discovery of Atrial Fibrillation After Stroke Open
Background and Purpose— Diagnosing paroxysmal atrial fibrillation (pAF) can be challenging after acute ischemic stroke. Enhanced and prolonged Holter-ECG monitoring (EPM) improves the detection rate but is not feasible for all patients. We…
View article: NfL (Neurofilament Light Chain) Levels as a Predictive Marker for Long-Term Outcome After Ischemic Stroke
NfL (Neurofilament Light Chain) Levels as a Predictive Marker for Long-Term Outcome After Ischemic Stroke Open
Background and Purpose— Ischemic stroke causes major disability as a consequence of neuronal loss and recurrent ischemic events. Biomarkers predicting tissue damage or stroke recurrence might be useful to guide an individualized stroke the…
View article: Automatic detection of paroxysmal atrial fibrillation in patients with ischaemic stroke: better than routine diagnostic workup?
Automatic detection of paroxysmal atrial fibrillation in patients with ischaemic stroke: better than routine diagnostic workup? Open
Background and purpose Prolonged electrocardiogram ( ECG) monitoring after ischaemic stroke increases the diagnostic yield of paroxysmal atrial fibrillation ( pAF ). In order to facilitate the additional workload involved in ECG analysis d…
View article: Holter-electrocardiogram-monitoring in patients with acute ischaemic stroke (Find-AF RANDOMISED ): an open-label randomised controlled trial
Holter-electrocardiogram-monitoring in patients with acute ischaemic stroke (Find-AF RANDOMISED ): an open-label randomised controlled trial Open
Boehringer Ingelheim.
View article: Safety of endovascular treatment in acute stroke patients taking oral anticoagulants
Safety of endovascular treatment in acute stroke patients taking oral anticoagulants Open
Background The endovascular treatment of acute cerebral ischemia has been proven beneficial without major safety concerns. To date, the role of endovascular treatment in patients treated with oral anticoagulants, which may be associated wi…
View article: Diagnostische Lumbalpunktion
Diagnostische Lumbalpunktion Open
The diagnostic lumbar puncture is an important diagnostic tool in various neurological diseases, such as inflammatory processes of the central nervous system. Considering relevant contraindications and performed in a standardised manner, t…