Sonja Stieb
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View article: A comprehensive multifaceted technical evaluation framework for implementation of auto-segmentation models in radiotherapy
A comprehensive multifaceted technical evaluation framework for implementation of auto-segmentation models in radiotherapy Open
The framework provides a robust method for validating automatic segmentation models in radiotherapy. However, establishing standardized benchmarks and consensus guidelines within the radiotherapy community remains essential for proper clin…
View article: Optimizing Atlas Counts for MRI-Guided Atlas-Based Autosegmentation of Swallowing Muscles in Head and Neck Radiotherapy
Optimizing Atlas Counts for MRI-Guided Atlas-Based Autosegmentation of Swallowing Muscles in Head and Neck Radiotherapy Open
Purpose Radiotherapy-induced dysphagia can significantly impair head and neck (H&N) cancer patients’ quality of life. Despite the dose-dependent relationship between radiotherapy and dysphagia, swallowing structures are not routinely conto…
View article: Neoadjuvant chemoradiotherapy in combination with deep regional hyperthermia followed by surgery for rectal cancer: a systematic review and meta-analysis
Neoadjuvant chemoradiotherapy in combination with deep regional hyperthermia followed by surgery for rectal cancer: a systematic review and meta-analysis Open
View article: Therapy-Associated Saliva and Taste change Evaluation (TASTE) in head & neck cancer patients undergoing radiotherapy: a study protocol
Therapy-Associated Saliva and Taste change Evaluation (TASTE) in head & neck cancer patients undergoing radiotherapy: a study protocol Open
Background One of the main side effects of radiation therapy to the head and neck region is altered taste sensation. This causes significant morbidity and has profound effects on the quality of life (QoL) of patients. While radiation-assoc…
View article: The influence of radiation dose on taste impairment in a prospective observational study cohort of oropharyngeal cancer patients
The influence of radiation dose on taste impairment in a prospective observational study cohort of oropharyngeal cancer patients Open
To analyze the influence of radiation dose on late radiation-associated taste impairment in oropharyngeal cancer (OPC) patients treated with intensity-modulated radiotherapy (IMRT) using the taste bud bearing tongue mucosa as organ at risk…
View article: Mixed Effect Modeling of Dose and Linear Energy Transfer Correlations With Brain Image Changes After Intensity Modulated Proton Therapy for Skull Base Head and Neck Cancer
Mixed Effect Modeling of Dose and Linear Energy Transfer Correlations With Brain Image Changes After Intensity Modulated Proton Therapy for Skull Base Head and Neck Cancer Open
Our results suggest that the LETd effect could be of clinical significance for some patients; LETd assessment in clinical treatment plans should therefore be taken into consideration.
View article: 18FDG positron emission tomography mining for metabolic imaging biomarkers of radiation-induced xerostomia in patients with oropharyngeal cancer
18FDG positron emission tomography mining for metabolic imaging biomarkers of radiation-induced xerostomia in patients with oropharyngeal cancer Open
View article: NTCP Modeling of Late Effects for Head and Neck Cancer: A Systematic Review
NTCP Modeling of Late Effects for Head and Neck Cancer: A Systematic Review Open
View article: Novel Autosegmentation Spatial Similarity Metrics Capture the Time Required to Correct Segmentations Better Than Traditional Metrics in a Thoracic Cavity Segmentation Workflow
Novel Autosegmentation Spatial Similarity Metrics Capture the Time Required to Correct Segmentations Better Than Traditional Metrics in a Thoracic Cavity Segmentation Workflow Open
View article: PleThora: Pleural effusion and thoracic cavity segmentations in diseased lungs for benchmarking chest CT processing pipelines
PleThora: Pleural effusion and thoracic cavity segmentations in diseased lungs for benchmarking chest CT processing pipelines Open
This manuscript describes a dataset of thoracic cavity segmentations and discrete pleural effusion segmentations we have annotated on 402 computed tomography (CT) scans acquired from patients with non-small cell lung cancer. The segmentati…
View article: Development and validation of a contouring guideline for the taste bud bearing tongue mucosa
Development and validation of a contouring guideline for the taste bud bearing tongue mucosa Open
View article: A Dosimetric Comparison of Oral Cavity Sparing in the Unilateral Treatment of Early Stage Tonsil Cancer: IMRT, IMPT, and Tongue-Deviating Oral Stents
A Dosimetric Comparison of Oral Cavity Sparing in the Unilateral Treatment of Early Stage Tonsil Cancer: IMRT, IMPT, and Tongue-Deviating Oral Stents Open
View article: PleThora: Pleural effusion and thoracic cavity segmentations in diseased lungs for benchmarking chest CT processing pipelines
PleThora: Pleural effusion and thoracic cavity segmentations in diseased lungs for benchmarking chest CT processing pipelines Open
This manuscript describes a dataset of thoracic cavity segmentations and discrete pleural effusion segmentations we have annotated on 402 computed tomography (CT) scans acquired from patients with non‐small cell lung cancer. The segmentati…
View article: Black bone MRI morphometry for mandibular cortical bone measurement in head and neck cancer patients: Prospective method comparison with CT
Black bone MRI morphometry for mandibular cortical bone measurement in head and neck cancer patients: Prospective method comparison with CT Open
Objectives To determine the utility of low-flip angle “black bone” magnetic resonance imaging (MRI) for cortical mandibular bone assessment by comparing interdentium cortical measurements and inter-observer morphometric variability in rela…
View article: Fully automatic classification of breast MRI background parenchymal enhancement using a transfer learning approach
Fully automatic classification of breast MRI background parenchymal enhancement using a transfer learning approach Open
Marked enhancement of the fibroglandular tissue on contrast-enhanced breast magnetic resonance imaging (MRI) may affect lesion detection and classification and is suggested to be associated with higher risk of developing breast cancer. The…
View article: Outcomes and patterns of radiation associated brain image changes after proton therapy for head and neck skull base cancers
Outcomes and patterns of radiation associated brain image changes after proton therapy for head and neck skull base cancers Open
View article: The impact of tongue-deviating and tongue-depressing oral stents on long-term radiation-associated symptoms in oropharyngeal cancer survivors
The impact of tongue-deviating and tongue-depressing oral stents on long-term radiation-associated symptoms in oropharyngeal cancer survivors Open
View article: 18FDG Positron Emission Tomography Mining for Metabolic Imaging Biomarkers of Radiation-induced Xerostomia in Patients with Oropharyngeal Cancer
18FDG Positron Emission Tomography Mining for Metabolic Imaging Biomarkers of Radiation-induced Xerostomia in Patients with Oropharyngeal Cancer Open
Purpose Head and neck cancers (HNC) radiotherapy (RT) is associated with inevitable injury to parotid glands and subsequent xerostomia. We investigated the utility of standardized uptake values (SUV) derived from routinely performed 18-flu…
View article: Novel Autosegmentation Spatial Similarity Metrics Capture the Time Required to Correct Segmentations Better than Traditional Metrics in a Thoracic Cavity Segmentation Workflow
Novel Autosegmentation Spatial Similarity Metrics Capture the Time Required to Correct Segmentations Better than Traditional Metrics in a Thoracic Cavity Segmentation Workflow Open
Introduction Automated segmentation templates can save clinicians time compared to de novo segmentation but may still take substantial time to review and correct. It has not been thoroughly investigated which automated segmentation-correct…
View article: Prospective observational evaluation of radiation-induced late taste impairment kinetics in oropharyngeal cancer patients: Potential for improvement over time?
Prospective observational evaluation of radiation-induced late taste impairment kinetics in oropharyngeal cancer patients: Potential for improvement over time? Open
Radiation-induced taste impairment may improve over an extended time interval, but becomes relatively stable from year 5 post-RT. Direct characterization of RT-induced taste impairment and the calculation of normal tissue complication prob…
View article: Radiation associated brain image changes after proton therapy for skull base head and neck cancers
Radiation associated brain image changes after proton therapy for skull base head and neck cancers Open
Background and purpose To characterize patterns and outcomes of brain MR image changes after proton therapy (PT) for skull base head and neck cancer (HNC). Material and methods 127 patients treated with PT for HNC who had received at least…
View article: Imaging for Response Assessment in Radiation Oncology
Imaging for Response Assessment in Radiation Oncology Open
View article: Correction for fast pseudo-diffusive fluid motion contaminations in diffusion tensor imaging
Correction for fast pseudo-diffusive fluid motion contaminations in diffusion tensor imaging Open
View article: Imaging for Target Delineation and Treatment Planning in Radiation Oncology
Imaging for Target Delineation and Treatment Planning in Radiation Oncology Open
View article: Xerostomia Impacts Dysgeusia in Oropharyngeal Cancer Patients Treated with Proton Therapy
Xerostomia Impacts Dysgeusia in Oropharyngeal Cancer Patients Treated with Proton Therapy Open
View article: A Randomized Phase II Translational Research Study in Patients with Advanced Head and Neck Cancer to Investigate the Effects of Standard Chemoradiation and Add-on Concurrent Epidermal Growth Factor Receptor (EGFR) Inhibitor ± Consolidation EGFR Inhibitor
A Randomized Phase II Translational Research Study in Patients with Advanced Head and Neck Cancer to Investigate the Effects of Standard Chemoradiation and Add-on Concurrent Epidermal Growth Factor Receptor (EGFR) Inhibitor ± Consolidation EGFR Inhibitor Open
View article: Radiation Associated Brain Necrosis following Proton Therapy for Head and Neck Skull Base and Intracranial Tumors
Radiation Associated Brain Necrosis following Proton Therapy for Head and Neck Skull Base and Intracranial Tumors Open
View article: Impact of Human Papillomavirus Infection And Tobacco Exposure On Oropharyngeal Squamous Cell Carcinoma Biology From A Radiomics Perspective
Impact of Human Papillomavirus Infection And Tobacco Exposure On Oropharyngeal Squamous Cell Carcinoma Biology From A Radiomics Perspective Open
View article: Prospective Observational Registry Cohort Evaluation of Oral Stents as Method to Reduce Long-term Radiation-induced Toxicity in Oropharyngeal Cancer Patients
Prospective Observational Registry Cohort Evaluation of Oral Stents as Method to Reduce Long-term Radiation-induced Toxicity in Oropharyngeal Cancer Patients Open
View article: Perfusion CT radiomics as potential prognostic biomarker in head and neck squamous cell carcinoma
Perfusion CT radiomics as potential prognostic biomarker in head and neck squamous cell carcinoma Open
Perfusion CT radiomics as potential prognostic biomarker in head and neck squamous cell carcinoma