Sonja Zehetmayer
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View article: Gastrointestinal Barrier Disruption in Post‐<scp>COVID</scp> Syndrome Fatigue Patients
Gastrointestinal Barrier Disruption in Post‐<span>COVID</span> Syndrome Fatigue Patients Open
Background Post‐COVID Syndrome (PCS) is the term for a condition with persistent symptoms in a proportion of COVID‐19 patients after asymptomatic, mild, or severe disease courses. Numbers vary, but the current estimate is that after COVID‐…
View article: A randomized controlled pilot study investigating adherence to blood pressure diaries with personal pictures in stroke follow-up care
A randomized controlled pilot study investigating adherence to blood pressure diaries with personal pictures in stroke follow-up care Open
Summary Introduction Blood pressure (BP) management is essential in secondary stroke prevention. Strategies to ensure continuous home BP monitoring are needed. Few studies investigated factors influencing adherence to home BP management. T…
View article: Odontoid process type II and III fracture fixation using bone allograft screws versus cannulated screws: a biomechanical study
Odontoid process type II and III fracture fixation using bone allograft screws versus cannulated screws: a biomechanical study Open
Introduction Fractures of the odontoid process are associated with high non-union rates, challenging treatment, and high incidence of screw-related complications. The aim of this study was to compare the biomechanical competence of a singl…
View article: Assessing fatigue in myalgic encephalomyelitis/chronic fatigue syndrome patients before and after treatment with bright light therapy: A prospective randomized controlled crossover study
Assessing fatigue in myalgic encephalomyelitis/chronic fatigue syndrome patients before and after treatment with bright light therapy: A prospective randomized controlled crossover study Open
gov (NCT06635928).
View article: Comparison of usability and user-friendliness of three FeNO analyzers in a general population cohort of the LEAD study
Comparison of usability and user-friendliness of three FeNO analyzers in a general population cohort of the LEAD study Open
View article: Determination and Comparison of the Pathogen Spectrum Evaluated by Microbial Culture and Multiplex PCR During Bronchoscopy with Regard to Clinical Utility of Routine Bronchial Wash in Patients with Various Pulmonary Diseases
Determination and Comparison of the Pathogen Spectrum Evaluated by Microbial Culture and Multiplex PCR During Bronchoscopy with Regard to Clinical Utility of Routine Bronchial Wash in Patients with Various Pulmonary Diseases Open
Background/Objectives: Bronchial wash for microbiological cultivation and/or multiplex polymerase chain reaction (PCR) is often routinely performed during bronchoscopy independent of the indication for bronchoscopy. This study aimed to det…
View article: German Asthma Net: Characterisation of responders to anti-IL-5 and anti-IL-5(R) therapy
German Asthma Net: Characterisation of responders to anti-IL-5 and anti-IL-5(R) therapy Open
These results underscore that long-term anti-IL-5/IL-5(R) therapy reduces exacerbation and corticosteroid burden, especially in patients with severe disease and high type 2 inflammatory burden. Contrastingly, low baseline corticosteroid us…
View article: Why and how should we simulate platform trials? Learnings from EU-PEARL
Why and how should we simulate platform trials? Learnings from EU-PEARL Open
View article: Sex-based differences in lung cancer susceptibility and molecular genetics in the 2020s
Sex-based differences in lung cancer susceptibility and molecular genetics in the 2020s Open
Female Caucasian patients seem to have a higher susceptibility to lung cancer. Although the rate of genetic alterations is similar in both sexes, actionable driver mutations are significantly more common in women.
View article: A Serious Game for Emotion Regulation in Adolescents
A Serious Game for Emotion Regulation in Adolescents Open
Early adolescence is a major time for friendship development, and interpersonal emotion regulation (iER) is a vital skill for social interactions. Serious games are an exciting way to engage young people with psychoeducational content. The…
View article: Efficiency of multivariate tests in trials in progressive supranuclear palsy
Efficiency of multivariate tests in trials in progressive supranuclear palsy Open
View article: Frequency distribution of health disorders in primary care—its consistency and meaning for diagnostics and nomenclature
Frequency distribution of health disorders in primary care—its consistency and meaning for diagnostics and nomenclature Open
Summary RN Braun observed that frequencies of health disorders in general practice are so consistent that he called his discovery “Case Distribution Law”. Our study compares morbidity data from methodologically similar surveys in primary c…
View article: <scp>PD‐L1</scp> expression in patients with non‐small‐cell lung cancer is associated with sex and genetic alterations: A retrospective study within the Caucasian population
<span>PD‐L1</span> expression in patients with non‐small‐cell lung cancer is associated with sex and genetic alterations: A retrospective study within the Caucasian population Open
Background Programmed cell death‐ligand 1 (PD‐L1) expression is a well‐established biomarker for predicting responses to immune checkpoint inhibitors and certain targeted therapies. As a result, treatment strategies for patients vary based…
View article: Current state-of-the-art and gaps in platform trials: 10 things you should know, insights from EU-PEARL
Current state-of-the-art and gaps in platform trials: 10 things you should know, insights from EU-PEARL Open
View article: Efficiency of Multivariate Tests in Trials in Progressive Supranuclear Palsy
Efficiency of Multivariate Tests in Trials in Progressive Supranuclear Palsy Open
Measuring disease progression in clinical trials for testing novel treatments for multifaceted diseases as Progressive Supranuclear Palsy (PSP), remains challenging. In this study we assess a range of statistical approaches to compare outc…
View article: Evaluation of PD-1 T lymphocytes in bronchoalveolar lavage in lung cancer compared to benign lung diseases
Evaluation of PD-1 T lymphocytes in bronchoalveolar lavage in lung cancer compared to benign lung diseases Open
View article: Early Identification of Type 2 Diabetes Using Glycated Haemoglobin in Primary Care Medical Offices as a Proof of Feasibility in Austria
Early Identification of Type 2 Diabetes Using Glycated Haemoglobin in Primary Care Medical Offices as a Proof of Feasibility in Austria Open
Numerous studies have been carried out on determination of glycated haemoglobin to diagnose type 2 diabetes (T2D), among them the manuscript by Selvin et al [1]. They have led the American Diabetes Association (ADA) to recommend haemoglobi…
View article: MELD-Na Alterations on the Liver Transplant Waiting List and Their Impact on Listing Outcome
MELD-Na Alterations on the Liver Transplant Waiting List and Their Impact on Listing Outcome Open
Background: Dynamic MELD deterioration (Delta MELD) during waiting time was shown to have significant impact on post-transplant survival. The aim of this study was to analyze the impact of MELD-Na score alterations on waiting list outcomes…
View article: Preprocedural imaging modalities in patients undergoing iliocaval venous recanalization and stent placement
Preprocedural imaging modalities in patients undergoing iliocaval venous recanalization and stent placement Open
Purpose: To determine the diagnostic accuracy of preinterventional imaging modalities in patients being evaluated for iliocaval venous recanalization and stent placement. Methods: Consecutive patients with iliocaval postthrombotic obstruct…
View article: Supplementary Material for: Women in interventional pulmonology – results from a worldwide survey
Supplementary Material for: Women in interventional pulmonology – results from a worldwide survey Open
Background and Objectives: Gender inequality in medicine remains an issue. Despite the increasing proportion of female physicians, women still appear underrepresented in interventional pulmonology careers. To date, no data is available on …
View article: Psychiatric symptoms and comorbidities in patients with drug-resistant epilepsy in presurgical assessment—A prospective explorative single center study
Psychiatric symptoms and comorbidities in patients with drug-resistant epilepsy in presurgical assessment—A prospective explorative single center study Open
Introduction People with epilepsy (PWE) have a higher prevalence of psychiatric disorders. Some individuals with drug-resistant epilepsy might benefit from surgical interventions. The aim of this study was to perform an assessment of psych…
View article: Online control of the False Discovery Rate in group-sequential platform trials
Online control of the False Discovery Rate in group-sequential platform trials Open
When testing multiple hypotheses, a suitable error rate should be controlled even in exploratory trials. Conventional methods to control the False Discovery Rate assume that all p-values are available at the time point of test decision. In…
View article: Impact of adaptive filtering on power and false discovery rate in RNA-seq experiments
Impact of adaptive filtering on power and false discovery rate in RNA-seq experiments Open
Background In RNA-sequencing studies a large number of hypothesis tests are performed to compare the differential expression of genes between several conditions. Filtering has been proposed to remove candidate genes with a low expression l…
View article: Comparing compliance with the WHO surgical safety checklist and complication rates in gynecologic surgery between day and night shifts
Comparing compliance with the WHO surgical safety checklist and complication rates in gynecologic surgery between day and night shifts Open
View article: Comparison of pulmonary function test, diffusion capacity, blood gas analysis and CT scan in patients with and without persistent respiratory symptoms following COVID-19
Comparison of pulmonary function test, diffusion capacity, blood gas analysis and CT scan in patients with and without persistent respiratory symptoms following COVID-19 Open
Background Long-lasting symptoms following SARS-CoV2-infection have been described in several studies. However, there is only limited knowledge about the ongoing pathophysiology and the association with pathological findings in medical exa…
View article: Real‐life evaluation of molecular multiplex IgE test methods in the diagnosis of pollen associated food allergy
Real‐life evaluation of molecular multiplex IgE test methods in the diagnosis of pollen associated food allergy Open
Background Diagnosis of food allergies is challenging, as combining information from specific IgE (sIgE)‐sensitization pattern and skin prick tests (SPTs) with clinical history is necessary for a personalized management of allergic patient…
View article: SARS-CoV-2 Antibody and T Cell Response after a Third Vaccine Dose in Hemodialysis Patients Compared with Healthy Controls
SARS-CoV-2 Antibody and T Cell Response after a Third Vaccine Dose in Hemodialysis Patients Compared with Healthy Controls Open
Hemodialysis (HD) patients have an increased risk of severe SARS-CoV-2 infection. In this study, we assess the impact of a third vaccine dose (3D) on antibody levels and T cell response in HD patients and a healthy control group in a prosp…
View article: Severe Acute Respiratory Coronavirus-2 Antibody and T cell response after a third vaccine dose in hemodialysis patients compared with healthy controls
Severe Acute Respiratory Coronavirus-2 Antibody and T cell response after a third vaccine dose in hemodialysis patients compared with healthy controls Open
1. Abstract Hemodialysis patients (HD patients) have a high health risk from Severe Acute Respiratory Coronavirus-2 (SARS-CoV-2) infection. In this study, we assess the impact of a third vaccine dose (3D) on antibody levels and T cell resp…
View article: Comparative effectiveness of moderate hypofractionation with volumetric modulated arc therapy versus conventional 3D-radiotherapy after radical prostatectomy
Comparative effectiveness of moderate hypofractionation with volumetric modulated arc therapy versus conventional 3D-radiotherapy after radical prostatectomy Open
View article: Fraction of exhaled nitric oxide is associated with disease burden in the German Asthma Net severe asthma cohort
Fraction of exhaled nitric oxide is associated with disease burden in the German Asthma Net severe asthma cohort Open
In a severe asthma cohort of 1007 patients, high F(ENO) was associated with chronic rhinosinusitis/polyps, later asthma onset, poor lung function and asthma control, low quality of life, frequent exacerbations and the need for maintenance …