Sonya Krishnan
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View article: Untangling the Sources of HIV-related Cardiovascular Risk
Untangling the Sources of HIV-related Cardiovascular Risk Open
View article: A United States HIV provider survey of antiretroviral therapy management in people living with HIV with co-occurring conditions
A United States HIV provider survey of antiretroviral therapy management in people living with HIV with co-occurring conditions Open
Introduction Simplified HIV treatment guidelines favor integrase strand transfer inhibitors (INSTIs). However, non-infectious comorbidities and co-occurring conditions (i.e. pregnancy) often necessitate individualized antiretroviral therap…
View article: Clinical and laboratory risk factors for pulmonary tuberculosis recurrence in three pooled Indian cohorts
Clinical and laboratory risk factors for pulmonary tuberculosis recurrence in three pooled Indian cohorts Open
Some individuals with drug-susceptible pulmonary tuberculosis (PTB) experience tuberculosis recurrence. To evaluate the incidence of and risk factors for recurrence following completion of antituberculosis therapy, we pooled data from thre…
View article: Randomized Controlled Trial of Clinical Guidelines Versus Interactive Decision-Support for Improving Medical Trainees’ Confidence with Latent Tuberculosis Care
Randomized Controlled Trial of Clinical Guidelines Versus Interactive Decision-Support for Improving Medical Trainees’ Confidence with Latent Tuberculosis Care Open
View article: 1580. A national prospective HIV provider survey of antiretroviral therapy preferences for management of treatment naïve and experienced individuals with genotypic resistance
1580. A national prospective HIV provider survey of antiretroviral therapy preferences for management of treatment naïve and experienced individuals with genotypic resistance Open
Background HIV clinical practice guidelines outline broad treatment principles, but offer less explicit recommendations for complex patient situations. We hypothesize there is variability in antiretroviral (ARV) decision-making among exper…
View article: A National HIV Provider Survey of Antiretroviral Therapy Preferences for Management of Treatment-Naive and Experienced Individuals With Drug Resistance
A National HIV Provider Survey of Antiretroviral Therapy Preferences for Management of Treatment-Naive and Experienced Individuals With Drug Resistance Open
Background HIV clinical practice guidelines outline broad treatment principles but offer less explicit recommendations by permutations of encountered viral resistance. We hypothesize that there is variability in antiretroviral (ARV) regime…
View article: US Guidelines Fall Short on Short-Course Tuberculosis-Preventive Therapy
US Guidelines Fall Short on Short-Course Tuberculosis-Preventive Therapy Open
The provision of tuberculosis-preventive therapy (TPT) to vulnerable populations is critical for global control. Shorter-course TPT regimens are highly effective and improve completion rates. Despite incorporation of 1 month of rifapentine…
View article: An open label randomized controlled trial of atorvastatin versus aspirin in elite controllers and antiretroviral-treated people with HIV
An open label randomized controlled trial of atorvastatin versus aspirin in elite controllers and antiretroviral-treated people with HIV Open
Background: Residual inflammation in people with HIV (PWH) despite suppression of HIV replication is associated with many comorbidities including cardiovascular disease. Targeting inflammation may decrease the risk of cardiovascular diseas…
View article: Effect of the relationship between anaemia and systemic inflammation on the risk of incident tuberculosis and death in people with advanced HIV: a sub-analysis of the REMEMBER trial
Effect of the relationship between anaemia and systemic inflammation on the risk of incident tuberculosis and death in people with advanced HIV: a sub-analysis of the REMEMBER trial Open
National Institutes of Health.
View article: 1-Year Incidence of Tuberculosis Infection and Disease Among Household Contacts of Rifampin- and Multidrug-Resistant Tuberculosis
1-Year Incidence of Tuberculosis Infection and Disease Among Household Contacts of Rifampin- and Multidrug-Resistant Tuberculosis Open
Background Tuberculosis infection (TBI) and TB disease (TBD) incidence remains poorly described following household contact (HHC) rifampin-/multidrug-resistant TB exposure. We sought to characterize TBI and TBD incidence at 1 year in HHCs …
View article: Characterising cause of death among people treated for drug-susceptible TB in India
Characterising cause of death among people treated for drug-susceptible TB in India Open
View article: 439. Anal Dysplasia Screening Cascade within a Single-Center Outpatient HIV Clinic
439. Anal Dysplasia Screening Cascade within a Single-Center Outpatient HIV Clinic Open
Background HIV-positive men who have sex with men (MSM) are recommended to have anal Pap tests annually to screen for high-grade anal squamous intraepithelial lesions (HSIL). In this population, removal of HSIL reduces the risk of progress…
View article: Diagnostic biomarkers for active tuberculosis: progress and challenges
Diagnostic biomarkers for active tuberculosis: progress and challenges Open
View article: Isoniazid Adherence Reduces Mortality and Incident Tuberculosis at 96 Weeks Among Adults Initiating Antiretroviral Therapy With Advanced Human Immunodeficiency Virus in Multiple High-Burden Settings
Isoniazid Adherence Reduces Mortality and Incident Tuberculosis at 96 Weeks Among Adults Initiating Antiretroviral Therapy With Advanced Human Immunodeficiency Virus in Multiple High-Burden Settings Open
Background People with human immunodeficiency virus (HIV) and advanced immunosuppression initiating antiretroviral therapy (ART) remain vulnerable to tuberculosis (TB) and early mortality. To improve early survival, isoniazid preventive th…
View article: Risk factors for surgical intervention in patients with primary spinal infection on initial presentation
Risk factors for surgical intervention in patients with primary spinal infection on initial presentation Open
OBJECTIVE Treatment of primary spinal infection includes medical management with or without surgical intervention. The objective of this study was to identify risk factors for the eventual need for surgery in patients with primary spinal i…
View article: Impact of the Relationship between Anaemia and Systemic Inflammation on the Risk of Incident Tuberculosis and Death in Persons with Advanced HIV: A Sub-Analysis of the REMEMBER Trial
Impact of the Relationship between Anaemia and Systemic Inflammation on the Risk of Incident Tuberculosis and Death in Persons with Advanced HIV: A Sub-Analysis of the REMEMBER Trial Open
View article: Integrative Multi-Omics Reveals Serum Markers of Tuberculosis in Advanced HIV
Integrative Multi-Omics Reveals Serum Markers of Tuberculosis in Advanced HIV Open
Tuberculosis (TB) accounts for disproportionate morbidity and mortality among persons living with HIV (PLWH). Conventional methods of TB diagnosis, including smear microscopy and Xpert MTB/RIF, have lower sensitivity in PLWH. Novel high-th…
View article: ART in HIV-Positive Persons With Low Pretreatment Viremia: Results From the START Trial
ART in HIV-Positive Persons With Low Pretreatment Viremia: Results From the START Trial Open
Background: The benefit of immediate antiretroviral therapy (ART) at CD4 >500 cells/μL was established in the Strategic Timing of Antiretroviral Treatment (START) study. The benefits and risks of immediate ART in participants with low pret…
View article: Cosmeceutical Contact Dermatitis—Cautions To Herbals
Cosmeceutical Contact Dermatitis—Cautions To Herbals Open