Sierin Lim
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View article: Computations Meet Experiments to Advance the Enzymatic Depolymerization of Plastics One Atom at a Time
Computations Meet Experiments to Advance the Enzymatic Depolymerization of Plastics One Atom at a Time Open
Plastics are essential to modern life, yet poor disposal practices contribute to low recycling rates and environmental accumulation-biological degradation and by-product reuse offer a path to mitigate this global threat. This report highli…
View article: Interface‐Enhanced and Self‐Guided Growth of 2D Interlayer Heterostructure Wafers with Vertically Aligned Van Der Waals Layers
Interface‐Enhanced and Self‐Guided Growth of 2D Interlayer Heterostructure Wafers with Vertically Aligned Van Der Waals Layers Open
2D heterostructures have garnered significant interest in the scientific community owing to their exceptional carrier transport properties and tunable band alignment. The fabrication of these heterostructures on a wafer scale is crucial fo…
View article: A gender breakdown of unexpected benefits generated by work from home in STEM fields − A qualitative analysis of the WiMPBME Task Group survey
A gender breakdown of unexpected benefits generated by work from home in STEM fields − A qualitative analysis of the WiMPBME Task Group survey Open
The findings of the survey show the diversity of perceptions about remote working in STEM fields, while highlighting the importance of considering family dynamics, individual circumstances as well as gender when evaluating varied experienc…
View article: A Sustainable and Flexible Carbon Paper-Based Multifunctional Human–Machine Interface (HMI) Sensor
A Sustainable and Flexible Carbon Paper-Based Multifunctional Human–Machine Interface (HMI) Sensor Open
We have executed a cost-effective approach to produce a high-performance multifunctional human–machine interface (HMI) humidity sensor. The designed sensors were ecofriendly, flexible, and highly sensitive to variability in relative humidi…
View article: Revolutionizing healthcare: new media’s impact on public health in low and middle income countries (LMICs)
Revolutionizing healthcare: new media’s impact on public health in low and middle income countries (LMICs) Open
This book review introduces Digitalization of Medicine in Low- and Middle-Income Countries: Paradigm Changes in Healthcare and Biomedical Research, a multidisciplinary analysis of how digital technologies reshape healthcare in resource-lim…
View article: Bioengineering approach for the design of magnetic bacterial cellulose membranes
Bioengineering approach for the design of magnetic bacterial cellulose membranes Open
Biopolymer research has led to the development of novel products through innovative strategies. Their functionalization is typically achieved by physical/chemical methods that require harsh chemicals or mechanical treatments. These functio…
View article: Cellular Uptake of Phase‐Separating Peptide Coacervates (Adv. Sci. 42/2024)
Cellular Uptake of Phase‐Separating Peptide Coacervates (Adv. Sci. 42/2024) Open
Peptide Coacervates for Intracellular Therapeutic Delivery Peptide coacervate microdroplets (CMs) are promising vectors to deliver a broad range of macromolecular therapeutics inside cells, but the mechanism by which CMs enter cells has re…
View article: Cellular Uptake of Phase‐Separating Peptide Coacervates
Cellular Uptake of Phase‐Separating Peptide Coacervates Open
Peptide coacervates self‐assembling via liquid‐liquid phase separation are appealing intracellular delivery vehicles of macromolecular therapeutics (proteins, DNA, mRNA) owing to their non‐cytotoxicity, high encapsulation capacity, and eff…
View article: Modulation of<i>Ideonella sakaiensis</i>PETase active site flexibility and activity on morphologically distinct substrates by surface charge engineering
Modulation of<i>Ideonella sakaiensis</i>PETase active site flexibility and activity on morphologically distinct substrates by surface charge engineering Open
Enzymatic hydrolysis of polyethylene terephthalate (PET) waste is a compelling strategy for environmentally friendly recycling of a major pollutant. Here, we investigate the effects of surface charge point mutations both proximal and dista…
View article: Evaluating a polymicrobial biofilm model for structural components by co-culturing Komagataeibacter hansenii produced bacterial cellulose with Pseudomonas aeruginosa PAO1
Evaluating a polymicrobial biofilm model for structural components by co-culturing Komagataeibacter hansenii produced bacterial cellulose with Pseudomonas aeruginosa PAO1 Open
A polymicrobial biofilm model of Komagataeibacter hansenii and Pseudomonas aeruginosa was developed to understand whether a pre-existing matrix affects the ability of another species to build a biofilm. P. aeruginosa was inoculated onto th…
View article: Ferritin cages as building blocks for higher-order assembly through copper–sulfur bonds for HER analysis
Ferritin cages as building blocks for higher-order assembly through copper–sulfur bonds for HER analysis Open
An approach was reported for assembling higher-order protein structures on a Cu substrate using cysteine-modified Archaeoglobus fulgidus as building blocks for Cu–S bonds. Its assembly mechanism and electrochemical potential were investiga…
View article: Human antimicrobial peptide inactivation mechanism of enveloped viruses
Human antimicrobial peptide inactivation mechanism of enveloped viruses Open
This dataset provides the raw data supporting the paper: Human antimicrobial peptide inactivation mechanism of enveloped viruses. https://doi.org/10.1016/j.jcis.2023.11.055 It comprises the infectivity data (Figure 1), DLS data (Figure 2 a…
View article: Human antimicrobial peptide inactivation mechanism of enveloped viruses
Human antimicrobial peptide inactivation mechanism of enveloped viruses Open
This dataset provides the raw data supporting the paper: Human antimicrobial peptide inactivation mechanism of enveloped viruses. https://doi.org/10.1016/j.jcis.2023.11.055 It comprises the infectivity data (Figure 1), DLS data (Figure 2 a…
View article: Human antimicrobial peptide inactivation mechanism of enveloped viruses
Human antimicrobial peptide inactivation mechanism of enveloped viruses Open
LL-37 addition to Phi6 leads to curvature modification in the lipid bilayer, ultimately separating the envelope from the nucleocapsid. Additional biological assays confirm the loss of virus infectivity in the presence of LL-37, which coinc…
View article: Dataset for "Protein-Nanocage Stabilized Pickering Emulsions for Nutrient Delivery"
Dataset for "Protein-Nanocage Stabilized Pickering Emulsions for Nutrient Delivery" Open
Grant number: IZSEZ0_192944 Project title: Protein-Nanocage Stabilized Pickering Emulsions for Nutrient Delivery Beginning of the Scientific Exchange: 09-07-2022 End of the Scientific Exchange: 16-11-2022 The brief objectives of the curre…
View article: Dataset for "Protein-Nanocage Stabilized Pickering Emulsions for Nutrient Delivery"
Dataset for "Protein-Nanocage Stabilized Pickering Emulsions for Nutrient Delivery" Open
Grant number: IZSEZ0_192944 Project title: Protein-Nanocage Stabilized Pickering Emulsions for Nutrient Delivery Beginning of the Scientific Exchange: 09-07-2022 End of the Scientific Exchange: 16-11-2022 The brief objectives of the curre…
View article: Thermostability enhancement of polyethylene terephthalate degrading PETase using self‐ and nonself‐ligating protein scaffolding approaches
Thermostability enhancement of polyethylene terephthalate degrading PETase using self‐ and nonself‐ligating protein scaffolding approaches Open
Polyethylene terephthalate (PET) hydrolase enzymes show promise for enzymatic PET degradation and green recycling of single‐use PET vessels representing a major source of global pollution. Their full potential can be unlocked with enzyme e…
View article: Electron Tunneling in Ferritin and Associated Biosystems
Electron Tunneling in Ferritin and Associated Biosystems Open
Ferritin is a 12 nanometer (nm) diameter iron storage protein complex that is found in most plants and animals. A substantial body of evidence has established that electrons can tunnel through and between ferritin protein nanoparticles and…
View article: Electron tunneling in ferritin and associated biosystems
Electron tunneling in ferritin and associated biosystems Open
Ferritin is a 12 nanometer (nm) diameter iron storage protein complex that is found in most plants and animals. A substantial body of evidence has established that electrons can tunnel through and between ferritin protein nanoparticles and…
View article: Electron tunneling in ferritin and associated biosystems
Electron tunneling in ferritin and associated biosystems Open
Ferritin is a 12 nanometer (nm) diameter iron storage protein complex that is found in most plants and animals. A substantial body of evidence has established that electrons can tunnel through and between ferritin protein nanoparticles and…
View article: Electron tunneling in ferritin and associated biosystems
Electron tunneling in ferritin and associated biosystems Open
Ferritin is a 12 nanometer (nm) diameter iron storage protein complex that is found in most plants and animals. A substantial body of evidence has established that electrons can tunnel through and between ferritin protein nanoparticles and…
View article: Temperature-Dependent Coherent Tunneling across Graphene–Ferritin Biomolecular Junctions
Temperature-Dependent Coherent Tunneling across Graphene–Ferritin Biomolecular Junctions Open
Understanding the mechanisms of charge transport (CT) across biomolecules in solid-state devices is imperative to realize biomolecular electronic devices in a predictive manner. Although it is well-accepted that biomolecule-electrode inter…
View article: The Role of Structural Order in the Mechanism of Charge Transport across Tunnel Junctions with Various Iron‐Storing Proteins
The Role of Structural Order in the Mechanism of Charge Transport across Tunnel Junctions with Various Iron‐Storing Proteins Open
In biomolecular electronics, the role of structural order in charge transport (CT) is poorly understood. It has been reported that the metal oxide cores of protein cages (e.g., iron oxide and ferrihydrite nanoparticles (NPs) present in fer…
View article: Cellular Uptake of His-Rich Peptide Coacervates Occurs by a Macropinocytosis-Like Mechanism
Cellular Uptake of His-Rich Peptide Coacervates Occurs by a Macropinocytosis-Like Mechanism Open
Coacervates are dense microdroplets formed by liquid-liquid phase separation (LLPS) of macromolecules that have gained increasing attention as drug delivery vehicles. Recently, we have reported a new intracellular delivery system based on …
View article: Biomolecular control over local gating in bilayer graphene induced by ferritin
Biomolecular control over local gating in bilayer graphene induced by ferritin Open
Electrical field-induced charge modulation in graphene-based devices at the nanoscale with ultrahigh density carrier accumulation is important for various practical applications. In bilayer graphene (BLG), inversion symmetry can simply be …