Sookyong Joo
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View article: Nuclear corepressors NCOR1 and NCOR2 entrain thymocyte signaling, selection, and emigration
Nuclear corepressors NCOR1 and NCOR2 entrain thymocyte signaling, selection, and emigration Open
T cell development proceeds via discrete stages that require both gene induction and gene repression. Transcription factors direct gene repression by associating with corepressor complexes containing chromatin-remodeling enzymes; the corep…
View article: Influenza infection recruits distinct waves of regulatory T cells to the lung that limit lung resident IgA+ B cells
Influenza infection recruits distinct waves of regulatory T cells to the lung that limit lung resident IgA+ B cells Open
The role of regulatory T cells (Tregs) in limiting responses to pathogens in tissues remains poorly described. We used scRNA-Seq and a newly generated Foxp3 -lineage reporter line ( Foxp3-iDTR mice) to track Tregs in the lungs and peripher…