Sophia C. Kamran
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View article: PrecisionPro Fusion: Clinical validation of an automated, rigid, Prostate-Specific MRI-CT Fusion system for prostate radiotherapy planning
PrecisionPro Fusion: Clinical validation of an automated, rigid, Prostate-Specific MRI-CT Fusion system for prostate radiotherapy planning Open
View article: Urethra contours on MRI: Multidisciplinary consensus educational atlas and reference standard for artificial intelligence benchmarking
Urethra contours on MRI: Multidisciplinary consensus educational atlas and reference standard for artificial intelligence benchmarking Open
View article: Post-hoc Estimation of a Quantitative Restriction Spectrum Imaging Biomarker for Prostate Cancer Detection Using Conventional MRI
Post-hoc Estimation of a Quantitative Restriction Spectrum Imaging Biomarker for Prostate Cancer Detection Using Conventional MRI Open
Background Multiparametric MRI is useful for early detection of clinically significant prostate cancer (csPCa), but its standard Apparent Diffusion Coefficient (ADC) has limited utility as a quantitative metric for automated, patient-level…
View article: 3D-bioprinted bone scaffolds: redefining paediatric orthopaedics reconstruction
3D-bioprinted bone scaffolds: redefining paediatric orthopaedics reconstruction Open
View article: Urethra contours on MRI: multidisciplinary consensus educational atlas and reference standard for artificial intelligence benchmarking
Urethra contours on MRI: multidisciplinary consensus educational atlas and reference standard for artificial intelligence benchmarking Open
Introduction The urethra is a recommended avoidance structure for prostate cancer treatment. However, even subspecialist physicians often struggle to accurately identify the urethra on available imaging. Automated segmentation tools show p…
View article: First-Generation and Low-Income Students in the National Medical Student Body
First-Generation and Low-Income Students in the National Medical Student Body Open
Importance Diverse representation within the US medical student body and physician workforce is an important step to help address known pervasive health care disparities. Objective To evaluate US medical school first-year matriculants betw…
View article: PURE-MRI: An International Study Assessing Physician Accuracy in Delineating the Prostate and Urethra on Prostate MRI
PURE-MRI: An International Study Assessing Physician Accuracy in Delineating the Prostate and Urethra on Prostate MRI Open
Purpose Precise delineation of genitourinary structures during prostate cancer (PCa) care is critical to optimize treatment delivery while minimizing toxicity and injury. The Prostate and UREthra on MRI (PURE-MRI) study was an internationa…
View article: National Institutes of Health Funding to Support Radiation Oncology Research: A Comparative Trend Analysis Over a Decade, 2011-2021
National Institutes of Health Funding to Support Radiation Oncology Research: A Comparative Trend Analysis Over a Decade, 2011-2021 Open
Despite radiation therapy's essential role in multidisciplinary cancer care, NIH, and National Cancer Institute funding to support radiation oncology research has remained disproportionally low over the last decade. These data may be usefu…
View article: Multidisciplinary Consensus Prostate Contours on Magnetic Resonance Imaging: Educational Atlas and Reference Standard for Artificial Intelligence Benchmarking
Multidisciplinary Consensus Prostate Contours on Magnetic Resonance Imaging: Educational Atlas and Reference Standard for Artificial Intelligence Benchmarking Open
View article: PSO-Net: Development of an automated psoriasis assessment system using attention-based interpretable deep neural networks
PSO-Net: Development of an automated psoriasis assessment system using attention-based interpretable deep neural networks Open
Psoriasis is a chronic skin condition that requires long-term treatment and monitoring. Although, the Psoriasis Area and Severity Index (PASI) is utilized as a standard measurement to assess psoriasis severity in clinical trials, it has ma…
View article: Genomic and demographic landscape of non-small cell lung cancer within an ethnically-diverse population – The implications for radiation oncology and personalised medicine
Genomic and demographic landscape of non-small cell lung cancer within an ethnically-diverse population – The implications for radiation oncology and personalised medicine Open
View article: Summary from the NCI clinical trials planning meeting on next generation of clinical trials in non-muscle invasive bladder cancer <sup/>
Summary from the NCI clinical trials planning meeting on next generation of clinical trials in non-muscle invasive bladder cancer <sup/> Open
The National Cancer Institute organized a virtual Clinical Trials Planning Meeting (CTPM) on ‘Defining the next generation of clinical trials with combination therapies in non-muscle invasive bladder cancer (NMIBC)’ led by the Bladder Canc…
View article: Advanced Restriction Imaging and Reconstruction Technology for Prostate Magnetic Resonance Imaging (ART-Pro): A Study Protocol for a Multicenter, Multinational Trial Evaluating Biparametric Magnetic Resonance Imaging and Advanced, Quantitative Diffusion Magnetic Resonance Imaging for the Detection of Prostate Cancer
Advanced Restriction Imaging and Reconstruction Technology for Prostate Magnetic Resonance Imaging (ART-Pro): A Study Protocol for a Multicenter, Multinational Trial Evaluating Biparametric Magnetic Resonance Imaging and Advanced, Quantitative Diffusion Magnetic Resonance Imaging for the Detection of Prostate Cancer Open
View article: Deep learning AI and Restriction Spectrum Imaging for patient-level detection of clinically significant prostate cancer on MRI
Deep learning AI and Restriction Spectrum Imaging for patient-level detection of clinically significant prostate cancer on MRI Open
Background The Prostate Imaging Reporting & Data System (PI-RADS), based on multiparametric MRI (mpMRI), is widely used for the detection of clinically significant prostate cancer (csPCa, Gleason Grade Group (GG≥2)). However, its diagnosti…
View article: US Cancer Mortality Trends Among Asian and Pacific Islander Populations
US Cancer Mortality Trends Among Asian and Pacific Islander Populations Open
Importance Cancer is the leading cause of death among Asian American individuals and the second leading cause of death among Native Hawaiian and Pacific Islander people. Objective To evaluate longitudinal cancer mortality trends from 1999 …
View article: Advanced Restriction imaging and reconstruction Technology for Prostate MRI (ART-Pro): Study protocol for a multicenter, multinational trial evaluating biparametric MRI and advanced, quantitative diffusion MRI for detection of prostate cancer
Advanced Restriction imaging and reconstruction Technology for Prostate MRI (ART-Pro): Study protocol for a multicenter, multinational trial evaluating biparametric MRI and advanced, quantitative diffusion MRI for detection of prostate cancer Open
Background Multiparametric MRI (mpMRI) is strongly recommended by current clinical guidelines for improved detection of clinically significant prostate cancer (csPCa). However, major limitations of mpMRI are the need for intravenous (IV) c…
View article: Restriction Spectrum Imaging as a quantitative biomarker for prostate cancer with reliable positive predictive value
Restriction Spectrum Imaging as a quantitative biomarker for prostate cancer with reliable positive predictive value Open
Background and Objective Positive predictive value of PI-RADS for clinically significant prostate cancer (csPCa, grade group [GG]≥2) varies widely between institutions and radiologists. The Restriction Spectrum Imaging restriction score (R…
View article: PROSTATE ADVANCED RADIATION TECHNOLOGIES INVESTIGATING QUALITY OF LIFE (PARTIQOL): PHASE III RCT OF PROTONS VS. IMRT FOR LOW/INTERMEDIATE-RISK PROSTATE CANCER
PROSTATE ADVANCED RADIATION TECHNOLOGIES INVESTIGATING QUALITY OF LIFE (PARTIQOL): PHASE III RCT OF PROTONS VS. IMRT FOR LOW/INTERMEDIATE-RISK PROSTATE CANCER Open
View article: Prognostic Significance of Immune Cell Infiltration in Muscle-invasive Bladder Cancer Treated with Definitive Chemoradiation: A Secondary Analysis of RTOG 0524 and RTOG 0712
Prognostic Significance of Immune Cell Infiltration in Muscle-invasive Bladder Cancer Treated with Definitive Chemoradiation: A Secondary Analysis of RTOG 0524 and RTOG 0712 Open
View article: The Role of Radiation Therapy in the Management of Prostate Cancer and Posttreatment Imaging Appearances
The Role of Radiation Therapy in the Management of Prostate Cancer and Posttreatment Imaging Appearances Open
Prostate cancer remains a significant global health concern, necessitating continuous research and innovation in treatment modalities. This review explores the currently employed techniques in radiation dose planning and tumor irradiation …
View article: Radiation Therapy for Stage IIA/B Seminoma: Modeling Secondary Cancer Risk for Protons and VMAT versus 3D Photons
Radiation Therapy for Stage IIA/B Seminoma: Modeling Secondary Cancer Risk for Protons and VMAT versus 3D Photons Open
Radiation therapy (RT) is an effective treatment for stage IIA and select stage IIB seminomas. However, given the long life expectancy of seminoma patients, there are concerns about the risk of secondary cancers from RT. This study assesse…
View article: A Multi-Institutional Survey of Radiation Oncology Professionals’ Knowledge, Attitudes, and Practice Behaviors Toward Sexual and Gender Minority Patients With Cancer
A Multi-Institutional Survey of Radiation Oncology Professionals’ Knowledge, Attitudes, and Practice Behaviors Toward Sexual and Gender Minority Patients With Cancer Open
Most staff feel comfortable in treating SGM patients but are less confident in the distinct needs of this population. Knowledge gaps persist for both clinicians and nonclinicians, indicating a need for further training specific to oncology…
View article: Radiation Therapy Summary of the AUA/ASTRO Guideline on Clinically Localized Prostate Cancer
Radiation Therapy Summary of the AUA/ASTRO Guideline on Clinically Localized Prostate Cancer Open
View article: Incidence and survival of secondary malignancies after external beam radiotherapy for prostate cancer in the Surveillance, Epidemiology, and End Results database
Incidence and survival of secondary malignancies after external beam radiotherapy for prostate cancer in the Surveillance, Epidemiology, and End Results database Open
Introduction: The study objective was to investigate the incidence of secondary bladder (BCa) and rectal cancers (RCa) after external beam radiotherapy (EBRT) for prostate cancer (PCa) compared to radical prostatectomy (RP) alone, and to c…
View article: Data from Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer
Data from Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer Open
Purpose:There is an urgent need for biomarkers of radiation response in organ-sparing therapies. Bladder preservation with trimodality therapy (TMT), consisting of transurethral tumor resection followed by chemoradiation, is an alternative…
View article: Supplementary Figure S12 from Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer
Supplementary Figure S12 from Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer Open
DDR Mutations and association with re-modified BI-EFS.
View article: Supplementary Figure S10 from Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer
Supplementary Figure S10 from Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer Open
Comparison of Patient Eligibility based on select DNA Damage Response (DDR) gene mutations for the Alliance A031701, RETAIN-BLADDER Trials and by mBI-EFS Favorable/Unfavorable Outcomes following TMT.
View article: Supplementary Figure S11 from Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer
Supplementary Figure S11 from Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer Open
Distribution of ERCC2 mutations present in TCGA Bladder.
View article: Supplementary Figure S2 from Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer
Supplementary Figure S2 from Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer Open
Comutation plot of MIBC TCGA genes.
View article: Supplementary Figure S11 from Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer
Supplementary Figure S11 from Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer Open
Distribution of ERCC2 mutations present in TCGA Bladder.