Sourav S. Patnaik
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View article: Ten-Year Follow-Up of Patients Following Craniotomies in the Sitting Position: A Real-World Data (RWD) Analysis
Ten-Year Follow-Up of Patients Following Craniotomies in the Sitting Position: A Real-World Data (RWD) Analysis Open
Background: The sitting position for craniotomies, although often surgically advantageous, can impose serious risks to patient safety. Objective(s): To evaluate long-term post-operative follow up in patients undergoing craniotomies in the …
View article: A Window into the Brain’s Microcirculation: Retinal Optical Coherence Tomography Angiography (OCTA) as Perioperative Bedside Resuscitation Guide?
A Window into the Brain’s Microcirculation: Retinal Optical Coherence Tomography Angiography (OCTA) as Perioperative Bedside Resuscitation Guide? Open
Objective Quantifying physiological flow dynamics in the brain’s microvasculature is vital for effective resuscitation management. Traditional resuscitation approaches rely on macrocirculatory flow targets, which often poorly correlate wit…
View article: Exploring nutritional supplement use for countering respiratory tract infections through an X (formerly Twitter)-based survey
Exploring nutritional supplement use for countering respiratory tract infections through an X (formerly Twitter)-based survey Open
View article: Health-promoting and medicinal properties of Zingiberaceae family plants: A minireview with a special focus on galangal, turmeric, cardamom, and ginger
Health-promoting and medicinal properties of Zingiberaceae family plants: A minireview with a special focus on galangal, turmeric, cardamom, and ginger Open
View article: In Vitro Pharmacological Modulation of PIEZO1 Channels in Frontal Cortex Neuronal Networks
In Vitro Pharmacological Modulation of PIEZO1 Channels in Frontal Cortex Neuronal Networks Open
PIEZO1 is a mechanosensitive ion channel expressed in various organs, including but not limited to the brain, heart, lungs, kidneys, bone, and skin. PIEZO1 has been implicated in astrocyte, microglia, capillary, and oligodendrocyte signali…
View article: Quantitative evaluation of ChatGPT versus Bard responses to anaesthesia-related queries
Quantitative evaluation of ChatGPT versus Bard responses to anaesthesia-related queries Open
View article: Planar Amorphous Silicon Carbide Microelectrode Arrays for Chronic Recording in Rat Motor Cortex
Planar Amorphous Silicon Carbide Microelectrode Arrays for Chronic Recording in Rat Motor Cortex Open
Chronic implantation of intracortical microelectrode arrays (MEAs) capable of recording from individual neurons can be used for the development of brain-machine interfaces. However, these devices show reduced recording capabilities under c…
View article: Isolation of the murine Glut1 deficient thalamocortical circuit: wavelet characterization and reverse glucose dependence of low and gamma frequency oscillations
Isolation of the murine Glut1 deficient thalamocortical circuit: wavelet characterization and reverse glucose dependence of low and gamma frequency oscillations Open
Glucose represents the principal brain energy source. Thus, not unexpectedly, genetic glucose transporter 1 (Glut1) deficiency (G1D) manifests with encephalopathy. G1D seizures, which constitute a prominent disease manifestation, often pro…
View article: Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC)
Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC) Open
Selective vascular access to the brain is desirable in metabolic tracer, pharmacological and other studies aimed to characterize neural properties in isolation from somatic influences from chest, abdomen or limbs. However, current methods …
View article: Comparison of ChatGPT vs. Bard to Anesthesia-related Queries
Comparison of ChatGPT vs. Bard to Anesthesia-related Queries Open
We investigated the ability of large language models (LLMs) to answer anesthesia related queries prior to surgery from a patient’s point of view. In the study, we introduced textual data evaluation metrics, investigated “hallucinations” ph…
View article: Isolation of the murine Glut1 deficient thalamocortical circuit: wavelet characterization and reverse glucose dependence of low and gamma frequency oscillations
Isolation of the murine Glut1 deficient thalamocortical circuit: wavelet characterization and reverse glucose dependence of low and gamma frequency oscillations Open
Glucose represents the principal brain energy source. Thus, not unexpectedly, genetic glucose transporter 1 (Glut1) deficiency (G1D) manifests with encephalopathy. G1D seizures, which constitute a prominent disease manifestation, often pro…
View article: Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC)
Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC) Open
Selective vascular access to the brain is desirable in metabolic tracer, pharmacological and other studies aimed to characterize neural properties in isolation from somatic influences from chest, abdomen or limbs. However, current methods …
View article: The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis
The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis Open
View article: Characterization of Active Electrode Yield for Intracortical Arrays: Awake versus Anesthesia
Characterization of Active Electrode Yield for Intracortical Arrays: Awake versus Anesthesia Open
Intracortical microelectrode arrays are used for recording neural signals at single-unit resolution and are promising tools for studying brain function and developing neuroprosthetics. Research is being done to increase the chronic perform…
View article: Experimental aortic aneurysm severity and growth depend on topical elastase concentration and lysyl oxidase inhibition
Experimental aortic aneurysm severity and growth depend on topical elastase concentration and lysyl oxidase inhibition Open
View article: Patient-Specific Computational Analysis of Hemodynamics in Adult Pulmonary Hypertension
Patient-Specific Computational Analysis of Hemodynamics in Adult Pulmonary Hypertension Open
View article: Influence of Implantation Depth on the Performance of Intracortical Probe Recording Sites
Influence of Implantation Depth on the Performance of Intracortical Probe Recording Sites Open
Microelectrode arrays (MEAs) enable the recording of electrical activity from cortical neurons which has implications for basic neuroscience and neuroprosthetic applications. The design space for MEA technology is extremely wide where devi…
View article: A Predictive Analysis of Wall Stress in Abdominal Aortic Aneurysms Using a Neural Network Model
A Predictive Analysis of Wall Stress in Abdominal Aortic Aneurysms Using a Neural Network Model Open
Rupture risk assessment of abdominal aortic aneurysms (AAAs) by means of quantifying wall stress is a common biomechanical strategy. However, the clinical translation of this approach has been greatly limited due to the complexity associat…
View article: Biomechanical properties of acellular scar ECM during the acute to chronic stages of myocardial infarction
Biomechanical properties of acellular scar ECM during the acute to chronic stages of myocardial infarction Open
View article: Animal Model Dependent Response to Pentagalloyl Glucose in Murine Abdominal Aortic Injury
Animal Model Dependent Response to Pentagalloyl Glucose in Murine Abdominal Aortic Injury Open
Abdominal aortic aneurysms (AAAs) are a local dilation of the aorta and are associated with significant mortality due to rupture and treatment complications. There is a need for less invasive treatments to prevent aneurysm growth and ruptu…
View article: Impacts of biomedical hashtag-based Twitter campaign: #DHPSP utilization for promotion of open innovation in digital health, patient safety, and personalized medicine
Impacts of biomedical hashtag-based Twitter campaign: #DHPSP utilization for promotion of open innovation in digital health, patient safety, and personalized medicine Open
View article: Ex Vivo Regional Mechanical Characterization of Porcine Pulmonary Arteries
Ex Vivo Regional Mechanical Characterization of Porcine Pulmonary Arteries Open
View article: A canonical correlation analysis of the relationship between clinical attributes and patient-specific hemodynamic indices in adult pulmonary hypertension
A canonical correlation analysis of the relationship between clinical attributes and patient-specific hemodynamic indices in adult pulmonary hypertension Open
View article: A Comparative Study of Biomechanical and Geometrical Attributes of Abdominal Aortic Aneurysms in the Asian and Caucasian Populations
A Comparative Study of Biomechanical and Geometrical Attributes of Abdominal Aortic Aneurysms in the Asian and Caucasian Populations Open
In this work, we provide a quantitative assessment of the biomechanical and geometric features that characterize abdominal aortic aneurysm (AAA) models generated from 19 Asian and 19 Caucasian diameter-matched AAA patients. 3D patient-spec…
View article: Biomechanical Restoration Potential of Pentagalloyl Glucose after Arterial Extracellular Matrix Degeneration
Biomechanical Restoration Potential of Pentagalloyl Glucose after Arterial Extracellular Matrix Degeneration Open
The objective of this study was to quantify pentagalloyl glucose (PGG) mediated biomechanical restoration of degenerated extracellular matrix (ECM). Planar biaxial tensile testing was performed for native (N), enzyme-treated (collagenase a…
View article: Mechanical Response of Porcine Liver Tissue under High Strain Rate Compression
Mechanical Response of Porcine Liver Tissue under High Strain Rate Compression Open
In automobile accidents, abdominal injuries are often life-threatening yet not apparent at the time of initial injury. The liver is the most commonly injured abdominal organ from this type of trauma. In contrast to current safety tests inv…
View article: Pentagalloyl Glucose and Its Functional Role in Vascular Health: Biomechanics and Drug-Delivery Characteristics
Pentagalloyl Glucose and Its Functional Role in Vascular Health: Biomechanics and Drug-Delivery Characteristics Open
View article: Quantitative Analysis of Tissue Damage Evolution in Porcine Liver With Interrupted Mechanical Testing Under Tension, Compression, and Shear
Quantitative Analysis of Tissue Damage Evolution in Porcine Liver With Interrupted Mechanical Testing Under Tension, Compression, and Shear Open
In this study, the damage evolution of liver tissue was quantified at the microstructural level under tensile, compression, and shear loading conditions using an interrupted mechanical testing method. To capture the internal microstructura…
View article: Infarcted rat myocardium: Data from biaxial tensile and uniaxial compressive testing and analysis of collagen fibre orientation
Infarcted rat myocardium: Data from biaxial tensile and uniaxial compressive testing and analysis of collagen fibre orientation Open
Myocardial infarction was experimentally induced in rat hearts and harvested immediately, 7, 14 and 28 days after the infarction induction. Anterior wall infarct samples underwent biaxial tensile and uniaxial compressive testing. Orientati…
View article: Functional Heart Valve Scaffolds Obtained by Complete Decellularization of Porcine Aortic Roots in a Novel Differential Pressure Gradient Perfusion System
Functional Heart Valve Scaffolds Obtained by Complete Decellularization of Porcine Aortic Roots in a Novel Differential Pressure Gradient Perfusion System Open
There is a great need for living valve replacements for patients of all ages. Such constructs could be built by tissue engineering, with perspective of the unique structure and biology of the aortic root. The aortic valve root is composed …