Souraya Sayegh
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View article: Relationship between SARC-F score and Peripheral Blood Lymphocytes in Juvenile Idiopathic Arthritis: An Observational Pilot Study
Relationship between SARC-F score and Peripheral Blood Lymphocytes in Juvenile Idiopathic Arthritis: An Observational Pilot Study Open
Background Given the relatively high prevalence of sarcopenia and immune profile abnormalities in inflammatory arthritis such as rheumatoid arthritis (RA), we investigated the relationship between exercise habits, SARC-F score and peripher…
View article: P095 Reciprocal relationship of skeletal muscle function and peripheral blood lymphocytes in juvenile idiopathic arthritis: an observational pilot study
P095 Reciprocal relationship of skeletal muscle function and peripheral blood lymphocytes in juvenile idiopathic arthritis: an observational pilot study Open
Background/Aims Chronic inflammation in ageing is associated with loss of skeletal muscle mass and function, known as sarcopenia. Sarcopenia is associated with multimorbidity. Juvenile idiopathic arthritis (JIA) is a chronic inflammatory d…
View article: Multiple outcomes of the germline <scp>p16<sup>INK4a</sup></scp> mutation affecting senescence and immunity in human skin
Multiple outcomes of the germline <span>p16<sup>INK4a</sup></span> mutation affecting senescence and immunity in human skin Open
The integrated behaviour of multiple senescent cell types within a single human tissue leading to the development of malignancy is unclear. Patients with Familial Melanoma Syndrome (FMS) have heterozygous germline defects in the CDKN2A gen…
View article: Vitamin <scp>D<sub>3</sub></scp> inhibits p38 <scp>MAPK</scp> and senescence‐associated inflammatory mediator secretion by senescent fibroblasts that impacts immune responses during ageing
Vitamin <span>D<sub>3</sub></span> inhibits p38 <span>MAPK</span> and senescence‐associated inflammatory mediator secretion by senescent fibroblasts that impacts immune responses during ageing Open
Vitamin D 3 replacement in older insufficient adults significantly improves their antigen‐specific varicella zoster virus (VZV) cutaneous immunity. However, the mechanisms involved in this enhancement of cutaneous immunity are not known. H…
View article: Evidence for tmTNF reverse signaling in vivo: Implications for an arginase-1-mediated therapeutic effect of TNF inhibitors during inflammation
Evidence for tmTNF reverse signaling in vivo: Implications for an arginase-1-mediated therapeutic effect of TNF inhibitors during inflammation Open
View article: Les cellules souches mésenchymateuses dérivées du tissu adipeux dans le traitement de la polyarthrite rhumatoïde : approches in vitro et in vivo
Les cellules souches mésenchymateuses dérivées du tissu adipeux dans le traitement de la polyarthrite rhumatoïde : approches in vitro et in vivo Open
La polyarthrite rhumatoïde (PR) est une maladie auto-immune inflammatoire caractérisée par une synovite chronique aboutissant à la dégradation du cartilage et une érosion osseuse. Malgré la présence de stratégies thérapeutiques capables de…
View article: Inhibition of Osteoclastogenesis by the RNA-Binding Protein QKI5: a Novel Approach to Protect from Bone Resorption
Inhibition of Osteoclastogenesis by the RNA-Binding Protein QKI5: a Novel Approach to Protect from Bone Resorption Open
Increased osteoclastogenesis is a common feature of bone erosion, notably in osteoporosis but also in inflammatory diseases such as rheumatoid arthritis (RA) and osteoarticular infections. Human cytomegalovirus (HCMV) infection has been de…
View article: Author response for "Inhibition of osteoclastogenesis by the RNA‐binding protein QKI5: a novel approach to protect from bone resorption"
Author response for "Inhibition of osteoclastogenesis by the RNA‐binding protein QKI5: a novel approach to protect from bone resorption" Open
View article: Corrigendum: Rheumatoid Synovial Fluids Regulate the Immunomodulatory Potential of Adipose-Derived Mesenchymal Stem Cells Through a TNF/NF-κB-Dependent Mechanism
Corrigendum: Rheumatoid Synovial Fluids Regulate the Immunomodulatory Potential of Adipose-Derived Mesenchymal Stem Cells Through a TNF/NF-κB-Dependent Mechanism Open
[This corrects the article DOI: 10.3389/fimmu.2019.01482.].
View article: Rheumatoid Synovial Fluids Regulate the Immunomodulatory Potential of Adipose-Derived Mesenchymal Stem Cells Through a TNF/NF-κB-Dependent Mechanism
Rheumatoid Synovial Fluids Regulate the Immunomodulatory Potential of Adipose-Derived Mesenchymal Stem Cells Through a TNF/NF-κB-Dependent Mechanism Open
[This corrects the article DOI: 10.3389/fimmu.2019.01482.].
View article: AB0040 JAK INHIBITORS – BARICITINIB AND TOFACITINIB – MODULATE THE IN VITRO INFLAMMATORY AND ALTERNATIVE POLARIZATIONS OF MACROPHAGES
AB0040 JAK INHIBITORS – BARICITINIB AND TOFACITINIB – MODULATE THE IN VITRO INFLAMMATORY AND ALTERNATIVE POLARIZATIONS OF MACROPHAGES Open
View article: P121 Rheumatoid synovial fluids differentially affect ADSC proliferation and immunomodulatory potential
P121 Rheumatoid synovial fluids differentially affect ADSC proliferation and immunomodulatory potential Open