Srdjan Postic
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View article: Presenilin-1 controls glucose metabolism and identity of pancreatic beta cells
Presenilin-1 controls glucose metabolism and identity of pancreatic beta cells Open
Presenilin 1 is an endoplasmic reticulum protein, most known for its role in pathogenesis of familial Alzheimer’s Disease (AD). Presenilin 1 has been attributed roles in intracellular calcium homeostasis in the brain, as well as in the pan…
View article: Effects of Arginine Vasopressin on Islet Cells in Pancreatic Tissue Slices: Glucose-Dependent Modulation of IP3 Receptor-Specific Responses
Effects of Arginine Vasopressin on Islet Cells in Pancreatic Tissue Slices: Glucose-Dependent Modulation of IP3 Receptor-Specific Responses Open
Arginine vasopressin (AVP) is well known for regulating fluid volume, osmotic balance, and vascular tone. Its role in the regulation of pancreatic α and β cell function has been reported, yet its effects are not fully understood, particula…
View article: Effects of Arginine Vasopressin on Islet Cells in Pancreatic Tissue Slices: Glucose-Dependent Modulation of IP3 Receptor-Specific Responses
Effects of Arginine Vasopressin on Islet Cells in Pancreatic Tissue Slices: Glucose-Dependent Modulation of IP3 Receptor-Specific Responses Open
Arginine vasopressin (AVP) is well known for regulating fluid volume, osmotic balance, and vascular tone. Its role in the regulation of pancreatic α and β cell function has been reported, yet its effects are not fully understood, particula…
View article: Critical transitions in pancreatic islets
Critical transitions in pancreatic islets Open
Calcium signals in pancreatic β cell collectives show a sharp transition from uncorrelated to correlated state resembling a phase transition as the slowly increasing glucose concentration crosses the tipping point. However, the exact natur…
View article: Effects of Arginine Vasopressin on Islet Cells in Pancreatic Tissue Slices: Glucose-Dependent Modulation of IP <sub>3</sub> Receptor-Specific Responses
Effects of Arginine Vasopressin on Islet Cells in Pancreatic Tissue Slices: Glucose-Dependent Modulation of IP <sub>3</sub> Receptor-Specific Responses Open
Arginine vasopressin (AVP) is well known for regulating fluid volume, osmotic balance, and vascular tone. Its role in the regulation of pancreatic α and β cell function has been reported, yet its effects are not fully understood, particula…
View article: Optical Stereometric Analysis of Milled and Not-Milled Copings for Removable Overdentures on an Experimental Partially Edentulous Mandible
Optical Stereometric Analysis of Milled and Not-Milled Copings for Removable Overdentures on an Experimental Partially Edentulous Mandible Open
Statement of problem: The stereo-optical method can be used for assessment of strains and deformations of different fixed or removable prosthodontic constructions. Material and methods: The study used two master casts of a lower jaw with b…
View article: The laboratory investigation of the capillarity of various dental solutions at three temperature levels
The laboratory investigation of the capillarity of various dental solutions at three temperature levels Open
Introduction/Objective. Many oblong micro-spaces of less than 500 ?m exist within oral cavity, such as dentine canalicular spaces, gaps, recesses, gingival sulcus etc. Since these spaces are susceptible to food and pathogenic microbe?s acc…
View article: Tracking Ca2+ Dynamics in NOD Mouse Islets During Spontaneous Diabetes Development
Tracking Ca2+ Dynamics in NOD Mouse Islets During Spontaneous Diabetes Development Open
The mechanisms accounting for the functional changes of α- and β-cells over the course of type 1 diabetes (T1D) development are largely unknown. Permitted by our established technology of high spatiotemporal resolution imaging of cytosolic…
View article: <strong>Tracking Ca2+ dynamics in NOD mouse islets during spontaneous diabetes development</strong>
<strong>Tracking Ca2+ dynamics in NOD mouse islets during spontaneous diabetes development</strong> Open
The mechanisms accounting for the functional changes of α- and β-cells over the course of Type 1 Diabetes (T1D) development are largely unknown. Permitted by our established technology of high spatiotemporal resolution imaging of cytosol…
View article: <strong>Tracking Ca2+ dynamics in NOD mouse islets during spontaneous diabetes development</strong>
<strong>Tracking Ca2+ dynamics in NOD mouse islets during spontaneous diabetes development</strong> Open
The mechanisms accounting for the functional changes of α- and β-cells over the course of Type 1 Diabetes (T1D) development are largely unknown. Permitted by our established technology of high spatiotemporal resolution imaging of cytosol…
View article: The connection between discolored gingiva of abutment teeth and the presence of cast post
The connection between discolored gingiva of abutment teeth and the presence of cast post Open
Background/Aim. The cause of discolored gingiva (DG) is the presence of metal in the gingival tissue. DG is a relatively common case and is caused by the deposition of amalgam material in the gingival tissue during dental application or or…
View article: Collective biological computation in metabolic economy
Collective biological computation in metabolic economy Open
Presented with sensory challenges, living cells employ extensive noisy, fluctuating signaling and communication among themselves to compute a physiologically proper response. Using coupled stochastic oscillators model, we propose that biol…
View article: High-resolution analysis of the cytosolic Ca <sup>2+</sup> events in β cell collectives in situ
High-resolution analysis of the cytosolic Ca <sup>2+</sup> events in β cell collectives in situ Open
Physiological glucose or ryanodine stimulation of β cell collectives generates a large number of [Ca 2+ ] c events, which can be rapidly assessed with our newly developed automatic image segmentation and [Ca 2+ ] c event identification pip…
View article: Physiological levels of adrenaline fail to stop pancreatic beta cell activity at unphysiologically high glucose levels
Physiological levels of adrenaline fail to stop pancreatic beta cell activity at unphysiologically high glucose levels Open
Adrenaline inhibits insulin secretion from pancreatic beta cells to allow an organism to cover immediate energy needs by unlocking internal nutrient reserves. The stimulation of α2-adrenergic receptors on the plasma membrane of beta cells …
View article: pH-Dependence of Glucose-Dependent Activity of Beta Cell Networks in Acute Mouse Pancreatic Tissue Slice
pH-Dependence of Glucose-Dependent Activity of Beta Cell Networks in Acute Mouse Pancreatic Tissue Slice Open
Extracellular pH has the potential to affect various aspects of the pancreatic beta cell function. To explain this effect, a number of mechanisms was proposed involving both extracellular and intracellular targets and pathways. Here, we fo…
View article: Mandibular overdenture retained with precision balls and bar attachment
Mandibular overdenture retained with precision balls and bar attachment Open
Introduction. Milled precision bar with the lateral additions of two precision attachments could significantly contribute to the primary and secondary retention of partial denture and overdenture. This clinical case demonstrates stability …
View article: Dual Mode of Action of Acetylcholine on Cytosolic Calcium Oscillations in Pancreatic Beta and Acinar Cells In Situ
Dual Mode of Action of Acetylcholine on Cytosolic Calcium Oscillations in Pancreatic Beta and Acinar Cells In Situ Open
Cholinergic innervation in the pancreas controls both the release of digestive enzymes to support the intestinal digestion and absorption, as well as insulin release to promote nutrient use in the cells of the body. The effects of muscarin…
View article: Dual Mode of Action of Acetylcholine on Cytosolic Calcium Oscillations in Pancreatic Beta and Acinar Cells in Situ
Dual Mode of Action of Acetylcholine on Cytosolic Calcium Oscillations in Pancreatic Beta and Acinar Cells in Situ Open
Cholinergic innervation in pancreas controls both the release of digestive enzymes to support the intestinal digestion and absorption, as well as insulin release to promote nutrient use in the cells of the body. The effects of muscarinic r…
View article: High resolution analysis of the cytosolic Ca<sup>2+</sup>events in beta cell collectives in situ
High resolution analysis of the cytosolic Ca<sup>2+</sup>events in beta cell collectives in situ Open
The release of peptide hormones is predominantly regulated by a transient increase in cytosolic Ca 2+ concentration ([Ca 2+ ] c ). To trigger exocytosis, Ca 2+ ions enter the cytosol from intracellular Ca 2+ stores or from the extracellula…
View article: The OHIP-EDENT B&amp;H Questionnaire: Translation and Psychometric Properties in Treatment of Acrylic Complete Denture Wearers
The OHIP-EDENT B&H Questionnaire: Translation and Psychometric Properties in Treatment of Acrylic Complete Denture Wearers Open
Objectives. The OHIP-EDENT (the OHIP-EDENT B&H) translated from the original English language version was assessed in complete denture wearers before and after new denture manufacture and adjustments.Materials and Methods. A total of 117 a…
View article: Overdenture in terms of preparation and restoration of supporting teeth: Review report
Overdenture in terms of preparation and restoration of supporting teeth: Review report Open
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View article: Clinical Characteristics of Abutment Teeth with Gingival Discoloration
Clinical Characteristics of Abutment Teeth with Gingival Discoloration Open
Purpose The grey‐bluish discoloration of gingiva (known as “amalgam tattoo”) does not appear only in the presence of amalgam restorations. It may also be seen in cases of teeth restored with cast dowels and porcelain‐fused‐to‐metal (PFM) r…
View article: Evaluation of Helkimo anamnestic and dysfunction index in identical twins
Evaluation of Helkimo anamnestic and dysfunction index in identical twins Open
Introduction: In 1974 Marti Helkimo designed special questionnaires which were used for entering adequate contemporary data collected by medical history, analyzing the functions of the orofacial system and analyzing occlusion. Data were ev…
View article: Practical Bioremediation Course – Laboratory Exercises on Biodegradation of Cationic Surfactant
Practical Bioremediation Course – Laboratory Exercises on Biodegradation of Cationic Surfactant Open
From the perspective of the lab exercises leader and teaching assistant for the Bioremediation course, it was very difficult to design and conduct a set of exercises that would fit the course curriculum and satisfactorily demonstrate biore…
View article: Influence of the magnetic field on microorganisms in the oral cavity
Influence of the magnetic field on microorganisms in the oral cavity Open
Magnets reduce the number of microbes and might be recommended as a supplement in therapy for reduced periodontal tissues. This is important because periodontal tissues that are in good conditions provide prolonged support to the oral tiss…