Srestha Dasgupta
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View article: Satellite glial contact enhances differentiation and maturation of human iPSC-derived sensory neurons
Satellite glial contact enhances differentiation and maturation of human iPSC-derived sensory neurons Open
Sensory neurons generated from induced pluripotent stem cells (idSNs) are used to model human peripheral neuropathies; however, current differentiation protocols produce cells with an embryonic phenotype. Peripheral glia contact sensory ne…
View article: Microfluidic Cultures of Basal Forebrain Cholinergic Neurons for Assessing Retrograde Cell Death by Live Imaging
Microfluidic Cultures of Basal Forebrain Cholinergic Neurons for Assessing Retrograde Cell Death by Live Imaging Open
Neurons are highly polarized cells, with axons that may innervate distant target regions. In the brain, basal forebrain cholinergic neurons (BFCNs) possess extensive axons that project to several target regions such as the cortex, hippocam…
View article: ProNGF elicits retrograde axonal degeneration of basal forebrain neurons through p75 <sup>NTR</sup> and induction of amyloid precursor protein
ProNGF elicits retrograde axonal degeneration of basal forebrain neurons through p75 <sup>NTR</sup> and induction of amyloid precursor protein Open
Basal forebrain cholinergic neurons (BFCNs) extend long projections to multiple regions in the brain to regulate cognitive functions. Degeneration of BFCNs is seen with aging, after brain injury, and in neurodegenerative disorders. An incr…
View article: Satellite glial contact enhances differentiation and maturation of human iPSC-derived sensory neurons
Satellite glial contact enhances differentiation and maturation of human iPSC-derived sensory neurons Open
Sensory neurons generated from induced pluripotent stem cells (iSNs) are used to model human peripheral neuropathies, however current differentiation protocols produce sensory neurons with an embryonic phenotype. Peripheral glial cells con…
View article: Cortical Brain Injury Causes Retrograde Degeneration of Afferent Basal Forebrain Cholinergic Neurons via the p75NTR
Cortical Brain Injury Causes Retrograde Degeneration of Afferent Basal Forebrain Cholinergic Neurons via the p75NTR Open
Traumatic brain injury (TBI) elicits neuronal loss at the site of injury and progressive neuronal loss in the penumbra. However, the consequences of TBI on afferent neurons projecting to the injured tissue from distal locations is unknown.…