2024-06-27
Exploring the role of new angiogenic tracer, 68Ga-DOTAGA-IAC and comparison of its diagnostic performance with 18F-FDG PET/CT in patients with radioiodine refractory differentiated thyroid carcinoma
2024-06-27 • Srinivas Ananth Kumar, Ashwani Sood, Rajender Kumar, Jaya Shukla, Bhagwant Rai Mittal
<title>Abstract</title> Introduction: Integrin antagonist carbamate (IAC) – a newer αvβ3 integrin antagonist peptidomimetic molecule in the pipeline, has made the molecular imaging of tumour angiogenesis amenable. The study aims to investigate the biodistribution, clinical efficacy of 68Ga DOTAGA-IAC PET/CT in the detection of radioiodine refractory differentiated thyroid carcinoma (RAIR-DTC), to compare its diagnostic performance with the most commonly used imaging tool, 18F-FDG PET/CT. Materials and methods: Thi…