Sriram Yennurajalingam
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View article: Psychological Interventions for Insomnia in Patients with Cancer: A Scoping Review
Psychological Interventions for Insomnia in Patients with Cancer: A Scoping Review Open
Background/Objectives: Insomnia is a frequent and distressing symptom with limited treatment in patients with cancer. Among the available treatments for insomnia, psychological interventions are some of the most assessed. While studies and…
View article: Putting Methylphenidate for Cancer-Related Fatigue to Rest?
Putting Methylphenidate for Cancer-Related Fatigue to Rest? Open
In the article that accompanies this editorial, Stone et al. present a randomized, double-blind, placebo-controlled trial of individually dose-titrated methylphenidate for treatment of fatigue in patients with advanced cancer, finding that…
View article: Scheduled and Breakthrough Opioid Use for Cancer Pain in an Inpatient Setting at a Tertiary Cancer Hospital
Scheduled and Breakthrough Opioid Use for Cancer Pain in an Inpatient Setting at a Tertiary Cancer Hospital Open
Background: Our aim was to examine the frequency and prescription pattern of breakthrough (BTO) and scheduled (SCH) opioids and their ratio (BTO/SCH ratio) of use, prior to and after referral to an inpatient supportive care consult (SCC) f…
View article: Access to Palliative Care in Low- and Middle-Income Countries during Coronavirus Disease-2019 Pandemic and Post-Pandemic Era: A Kenyan Experience
Access to Palliative Care in Low- and Middle-Income Countries during Coronavirus Disease-2019 Pandemic and Post-Pandemic Era: A Kenyan Experience Open
The coronavirus disease-2019 (COVID-19) pandemic emphasized the role of palliative care as an essential service to patients and families affected by life-threatening illnesses. Challenges encountered included: patients were not able to acc…
View article: Perception of subjective lived experiences of individuals with anorexia-cachexia in patients with advanced lung cancer
Perception of subjective lived experiences of individuals with anorexia-cachexia in patients with advanced lung cancer Open
View article: Management of cancer pain in pregnancy: can opioids be used?
Management of cancer pain in pregnancy: can opioids be used? Open
Cancer in pregnancy is less common, however its frequency is increasing due to delayed onset of childbearing. Pregnant patients with cancer can experience high frequency of moderate to severe cancer pain. It can be challenging to manage ca…
View article: Helpfulness of Question Prompt Sheet for Patient-Physician Communication Among Patients With Advanced Cancer
Helpfulness of Question Prompt Sheet for Patient-Physician Communication Among Patients With Advanced Cancer Open
Importance There are few robust evaluations of disease-specific question prompt sheets (QPS) in patient-physician communication among patients with advanced cancer. Objective To compare the patient perception of helpfulness, global evaluat…
View article: Decision-Making Preferences among Advanced Cancer Patients in a Palliative Setting in Jordan
Decision-Making Preferences among Advanced Cancer Patients in a Palliative Setting in Jordan Open
Understanding patients’ decision-making preferences is crucial for enhancing patients’ outcomes. The current study aims to identify Jordanian advanced cancer patients’ preferred decision-making and to explore the associated variables of th…
View article: Meta-Analysis of Pharmacological, Nutraceutical and Phytopharmaceutical Interventions for the Treatment of Cancer Related Fatigue
Meta-Analysis of Pharmacological, Nutraceutical and Phytopharmaceutical Interventions for the Treatment of Cancer Related Fatigue Open
Purpose: In this study we aimed to estimate the effectiveness of pharmacological, nutraceutical, and phytopharmaceutical treatments on CRF. Methods: Ovid MEDLINE, Ovid Embase, Ovid Psych info, CINHAHL and Cochrane Library databases were se…
View article: Open-Label Placebo for the Treatment of Cancer-Related Fatigue in Patients with Advanced Cancer: A Randomized Controlled Trial
Open-Label Placebo for the Treatment of Cancer-Related Fatigue in Patients with Advanced Cancer: A Randomized Controlled Trial Open
Background The purpose of this study was to determine the effects of an open-labeled placebo (OLP) compared to a waitlist control (WL) in reducing cancer-related fatigue (CRF) in patients with advanced cancer using Functional Assessment of…
View article: Interdisciplinary intervention for the management of nonmedical opioid use among patients with cancer pain
Interdisciplinary intervention for the management of nonmedical opioid use among patients with cancer pain Open
Background Few studies have assessed interventions aimed at managing nonmedical opioid use (NMOU) behavior among patients with cancer. The authors developed the Compassionate High‐Alert Team (CHAT) intervention to manage patients receiving…
View article: Combination Therapy of Physical Activity and Dexamethasone for Cancer-Related Fatigue: A Phase II Randomized Double-Blind Controlled Trial
Combination Therapy of Physical Activity and Dexamethasone for Cancer-Related Fatigue: A Phase II Randomized Double-Blind Controlled Trial Open
Background: Despite the high frequency of cancer-related fatigue (CRF) and its debilitating effects on the quality of life of patients with advanced cancer, there are limited treatment options available. Treatments including physical activ…
View article: Frequency and characteristics of advanced cancer patients with COVID + ve status among inpatient supportive care consults during the pandemic: experience from a tertiary cancer center
Frequency and characteristics of advanced cancer patients with COVID + ve status among inpatient supportive care consults during the pandemic: experience from a tertiary cancer center Open
View article: Impact of “race” as a social variable for screening for the risk of non-medical opioid use using nomogram
Impact of “race” as a social variable for screening for the risk of non-medical opioid use using nomogram Open
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View article: Sleep Disturbance in Cancer Patients Referred to an Ambulatory Integrative Oncology Consultation
Sleep Disturbance in Cancer Patients Referred to an Ambulatory Integrative Oncology Consultation Open
Background Sleep disturbance (SD) is highly prevalent in oncology and negatively affects quality of life and mortality. Evidence supports the use of integrative oncology (IO) practices to treat SD, but there is limited published data on th…
View article: Genetic Factors Associated With Pain Severity, Daily Opioid Dose Requirement, and Pain Response Among Advanced Cancer Patients Receiving Supportive Care
Genetic Factors Associated With Pain Severity, Daily Opioid Dose Requirement, and Pain Response Among Advanced Cancer Patients Receiving Supportive Care Open
View article: Frequency of and Factors Associated With Nonmedical Opioid Use Behavior Among Patients With Cancer Receiving Opioids for Cancer Pain
Frequency of and Factors Associated With Nonmedical Opioid Use Behavior Among Patients With Cancer Receiving Opioids for Cancer Pain Open
This prognostic study of patients with cancer taking opioids for cancer pain found that 19% of patients developed NMOU behavior within a median duration of 8 weeks after initial supportive care clinic consultation. Marital status (single o…
View article: Fixed-Dose Netupitant and Palonosetron for Chronic Nausea in Cancer Patients: A Double-Blind, Placebo Run-in Pilot Randomized Clinical Trial
Fixed-Dose Netupitant and Palonosetron for Chronic Nausea in Cancer Patients: A Double-Blind, Placebo Run-in Pilot Randomized Clinical Trial Open
View article: Random urine drug testing among patients receiving opioid therapy for cancer pain
Random urine drug testing among patients receiving opioid therapy for cancer pain Open
Background There is limited information regarding the true frequency of nonmedical opioid use (NMOU) among patients receiving opioid therapy for cancer pain. Data to guide patient selection for urine drug testing (UDT) as well as the timin…
View article: Extension for Community Healthcare Outcomes-Palliative Care in Africa Program: Improving Access to Quality Palliative Care
Extension for Community Healthcare Outcomes-Palliative Care in Africa Program: Improving Access to Quality Palliative Care Open
PURPOSE There is limited access to quality palliative care (PC) for patients with advanced cancer in sub-Saharan Africa. Our aim was to describe the development of the Project Extension for Community Healthcare Outcomes-Palliative Care in …
View article: Prokinetics and ghrelin for the management of cancer cachexia syndrome
Prokinetics and ghrelin for the management of cancer cachexia syndrome Open
Cancer cachexia (CC) is one of the most distressing syndromes for both patients and their families. CC can have an impact on patient reported quality of life and overall survival. It is often associated with symptoms such as fatigue, depre…
View article: Patterns of Opioid Prescription, Use, and Costs Among Patients With Advanced Cancer and Inpatient Palliative Care Between 2008 and 2014
Patterns of Opioid Prescription, Use, and Costs Among Patients With Advanced Cancer and Inpatient Palliative Care Between 2008 and 2014 Open
PURPOSE: An understanding of opioid prescription and cost patterns is important to optimize pain management for patients with advanced cancer. This study aimed to determine opioid prescription and cost patterns and to identify opioid presc…
View article: Predicting the risk for aberrant opioid use behavior in patients receiving outpatient supportive care consultation at a comprehensive cancer center
Predicting the risk for aberrant opioid use behavior in patients receiving outpatient supportive care consultation at a comprehensive cancer center Open
BACKGROUND Opioid misuse is a growing crisis. Patients with cancer who are at risk of aberrant drug behaviors are frequently underdiagnosed. The primary objective of this study was to determine the frequency and factors predicting a risk f…
View article: Development and validation of a prognostic nomogram for ambulatory patients with advanced cancer
Development and validation of a prognostic nomogram for ambulatory patients with advanced cancer Open
Predicting survival of advanced cancer patients (ACPs) is a difficult task. We aimed at developing and testing a new prognostic tool in ACPs when they were first referred to palliative care (PC). A total of 497 patients were analyzed in th…
View article: Perception of Curability Among Advanced Cancer Patients: An International Collaborative Study
Perception of Curability Among Advanced Cancer Patients: An International Collaborative Study Open
Background There are limited data on illness understanding and perception of cure among advanced cancer patients around the world. The aim of the study was to determine the frequency and factors associated with inaccurate perception of cur…
View article: Timing of Referral and Characteristics of Uninsured, Medicaid, and Insured Patients Referred to the Outpatient Supportive Care Center at a Comprehensive Cancer Center
Timing of Referral and Characteristics of Uninsured, Medicaid, and Insured Patients Referred to the Outpatient Supportive Care Center at a Comprehensive Cancer Center Open
View article: Palliative radiation therapy in the last 30 days of life: A systematic review
Palliative radiation therapy in the last 30 days of life: A systematic review Open
View article: Cranial Electrotherapy Stimulation for the Management of Depression, Anxiety, Sleep Disturbance, and Pain in Patients With Advanced Cancer: A Preliminary Study
Cranial Electrotherapy Stimulation for the Management of Depression, Anxiety, Sleep Disturbance, and Pain in Patients With Advanced Cancer: A Preliminary Study Open
View article: A Double-Blind, Randomized, Placebo-Controlled Trial of<i>Panax Ginseng</i>for Cancer-Related Fatigue in Patients With Advanced Cancer
A Double-Blind, Randomized, Placebo-Controlled Trial of<i>Panax Ginseng</i>for Cancer-Related Fatigue in Patients With Advanced Cancer Open
Background: Despite the high frequency, severity, and effects of cancer-related fatigue (CRF) on the quality of life (QoL) of patients with cancer, limited treatment options are available. The primary objective of this study was to …
View article: Overall Survival among Cancer Patients Undergoing Opioid Rotation to Methadone Compared to Other Opioids
Overall Survival among Cancer Patients Undergoing Opioid Rotation to Methadone Compared to Other Opioids Open
We observed no significant difference in OS in cancer patients in methadone group compared to other opioids.