Stacey M. Frumm
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View article: Medical student motivation in specialised contexts
Medical student motivation in specialised contexts Open
Purpose During their clinical years, medical students rotate in diverse environments, each with unique factors motivating or demotivating learning. Student motivation to learn in specialised clinical settings has not been robustly describe…
View article: Epimorphic regeneration in the mammalian tympanic membrane
Epimorphic regeneration in the mammalian tympanic membrane Open
View article: Supplementary Figures 1 -11 from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
Supplementary Figures 1 -11 from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition Open
PDF file - 326K, This file contains 11 supplementary figures with biochemistry, computational analysis, in vitro and in vivo studies to support the role of targeting MYCN in neuroblastoma with BETi.
View article: Supplementary Figure Legend from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
Supplementary Figure Legend from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition Open
PDF file - 35K
View article: Data from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
Data from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition Open
Bromodomain inhibition comprises a promising therapeutic strategy in cancer, particularly for hematologic malignancies. To date, however, genomic biomarkers to direct clinical translation have been lacking. We conducted a cell-based screen…
View article: Supplementary Figure Legend from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
Supplementary Figure Legend from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition Open
PDF file - 35K
View article: Supplementary Tables 1 - 9 from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
Supplementary Tables 1 - 9 from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition Open
PDF file - 93K, This file contains 9 supplementary tables including the full primary screening data and secondary testing of BETi in neuroblastoma, supporting tables for the expression profiling analyses, and the list of Affymetrix probes …
View article: Data from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
Data from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition Open
Bromodomain inhibition comprises a promising therapeutic strategy in cancer, particularly for hematologic malignancies. To date, however, genomic biomarkers to direct clinical translation have been lacking. We conducted a cell-based screen…
View article: Supplementary Tables 1 - 9 from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
Supplementary Tables 1 - 9 from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition Open
PDF file - 93K, This file contains 9 supplementary tables including the full primary screening data and secondary testing of BETi in neuroblastoma, supporting tables for the expression profiling analyses, and the list of Affymetrix probes …
View article: Supplementary Figures 1 -11 from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
Supplementary Figures 1 -11 from Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition Open
PDF file - 326K, This file contains 11 supplementary figures with biochemistry, computational analysis, in vitro and in vivo studies to support the role of targeting MYCN in neuroblastoma with BETi.
View article: A Hierarchy of Proliferative and Migratory Keratinocytes Maintains the Tympanic Membrane
A Hierarchy of Proliferative and Migratory Keratinocytes Maintains the Tympanic Membrane Open
View article: Rapid deployment of SARS-CoV-2 testing: The CLIAHUB
Rapid deployment of SARS-CoV-2 testing: The CLIAHUB Open
Author(s): Crawford, Emily D; Acosta, Irene; Ahyong, Vida; Anderson, Erika C; Arevalo, Shaun; Asarnow, Daniel; Axelrod, Shannon; Ayscue, Patrick; Azimi, Camillia S; Azumaya, Caleigh M; Bachl, Stefanie; Bachmutsky, Iris; Bhaduri, Aparna; Br…
View article: Development of the Mouse and Human Cochlea at Single Cell Resolution
Development of the Mouse and Human Cochlea at Single Cell Resolution Open
Summary Hearing loss is a common and disabling condition, yet our understanding of the physiologic workings of the inner ear has been limited by longstanding difficulty characterizing the function and characteristics of the many diverse, f…
View article: A hierarchy of migratory keratinocytes maintains the tympanic membrane
A hierarchy of migratory keratinocytes maintains the tympanic membrane Open
Summary Although the conductive function of the tympanic membrane (TM) is critical for hearing, it is unknown how the organ maintains cellular homeostasis. Using a combination of single-cell RNA sequencing, lineage tracing, whole-organ exp…
View article: Targeting MTHFD2 in acute myeloid leukemia
Targeting MTHFD2 in acute myeloid leukemia Open
Drugs targeting metabolism have formed the backbone of therapy for some cancers. We sought to identify new such targets in acute myeloid leukemia (AML). The one-carbon folate pathway, specifically methylenetetrahydrofolate dehydrogenase-cy…
View article: Targeting MTHFD2 in acute myeloid leukemia
Targeting MTHFD2 in acute myeloid leukemia Open
Drugs targeting metabolism have formed the backbone of therapy for some cancers. We sought to identify new such targets in acute myeloid leukemia (AML). The one-carbon folate pathway, specifically methylenetetrahydrofolate dehydrogenase-cy…