Explanipedia

A Social Media Campaign and Web-Based Survey About Prostate Cancer Genetics: Mixed Methods Study Open

Amy Leader, Stacy Loeb, Preethi Selvan, Ashley Hunter, Rebecca Hartman , et al. · 2025

Background Germline genetic variants are important for prostate cancer (PCa) management and hereditary cancer risk assessment, but testing is underused. Furthermore, patients are often unaware of the genetic connections to PCa. Social medi…

Barriers and Facilitators of Treatment Intensification in Metastatic Castration-Sensitive Prostate Cancer Open

Stacy Loeb, Neeraj Agarwal, Nader N. El-Chaar, Laura de Ruiter, Janet Kim , et al. · 2025

Importance Despite evidence of clinical benefits and guidelines recommending first-line treatment intensification (TI) for metastatic castration-sensitive prostate cancer (mCSPC), the majority of patients do not receive it. Objective To id…

Classification of Inaccurate Information About Prostate Cancer on Social Media in English and Spanish Open

Stacy Loeb, Mariana Rangel Camacho, Tatiana Sanchez Nolasco, Nataliya Byrne, Adrian Rivera , et al. · 2025

Inaccurate information about prostate cancer is widespread on online social networks in English and Spanish and spans a variety of topics from prevention and screening to treatment and survivorship. Clinicians should raise awareness that s…

Downstream Impact of Social Media Use and Variable Quality of Online Information About Prostate Cancer Open

Stacy Loeb, Mariana Rangel Camacho, Tatiana Sanchez Nolasco, Nataliya Byrne, Adrian Rivera , et al. · 2025

Social media can benefit prostate cancer care through education and empowerment, but also have the potential for exposure to misinformation, leading to adverse health and/or economic impacts for patients and damaging the patient-physician …

Diet and Prevention of Cardiovascular Disease and Cancer Open

Sarah C. Hull, Reed Mszar, Robert J. Ostfeld, Leah M. Ferrucci, Lorelei A. Mucci , et al. · 2025

Cardiovascular disease (CVD) and cancer remain the leading causes of mortality in the United States, where poor diet has surpassed smoking as the leading risk factor for death, and life expectancy has hit a plateau as CVD mortality has sta…

From launch to legacy: 10 years of The European Association of Urology Guidelines on social media Open

Clàudia Mercader, Jeremy Yuen‐Chun Teoh, Nikita Bhatt, Vito Cucchiara, Esther García‐Rojo , et al. · 2025

The Impact of the COVID-19 Pandemic on Genitourinary Cancer Care: Re-envisioning the Future Open

Christopher J.D. Wallis, James W.F. Catto, Antonio Finelli, Adam Glaser, John L. Gore , et al. · 2025

SIU-ICUD: Germline Genetic Susceptibility to Prostate Cancer: Utility and Clinical Implementation Open

James T. Kearns, Annabelle Ashworth, Elena Castro, Rosalind A. Eeles, Liesel M. FitzGerald , et al. · 2025

Background/Objectives: Prostate cancer is the most common cancer among men globally and a leading cause of cancer-related death. Germline genetic evaluation is increasingly recognized as essential for men with high-risk features such as a …

Germline testing for prostate cancer: current state and opportunities for enhanced access Open

Stacy Loeb, Susan T. Vadaparampil, Veda N. Giri · 2025

Germline Testing (GT) for prostate cancer (PCA) is now central to PCA care and hereditary cancer assessment, with a rising role in PCA screening approaches. Guidelines have significantly expanded to include testing patients with metastatic…

Disparities in tissue-based biomarker testing among US Medicare beneficiaries with prostate cancer Open

Stephan Korn, Zhiyu Qian, Hanna Zurl, Andrea Piccolini, Klara K Pohl , et al. · 2025

Background Personalized therapeutic approaches for localized prostate cancer have evolved significantly, with tissue-based biomarker tests supplementing traditional risk stratification tools. However, national testing patterns and geograph…

Prostate Cancer Foundation White Paper on Combination Therapy for Metastatic Hormone-Sensitive Prostate Cancer Open

Sigrid Carlsson, Pedro C. Barata, Alan H. Bryce, Daniel J. George, Silke Gillessen , et al. · 2025

Despite several randomized controlled trials demonstrating the benefits of combination therapies for metastatic hormone-sensitive prostate cancer (mHSPC), a significant treatment gap persists. This initiative by the Prostate Cancer Foundat…

Combating online misinformation in clinical encounters Open

Stacy Loeb, Mariana Rangel Camacho, Tatiana Sanchez Nolasco, Nataliya Byrne, Adrian Rivera , et al. · 2025

Carbon Emissions From Patient Travel for Health Care Open

Hanna Zurl, Zhiyu Qian, Daniel R. Stelzl, Filippo Dagnino, Stephan M. Korn , et al. · 2025

Importance The US health care sector accounts for about 8.5% of national greenhouse gas (GHG) emissions. Reliable estimates of emissions associated with health care–related travel are essential for informing policy changes. Objective To ge…

Quality of English‐ and Spanish‐language online content about prostate cancer genetics: Insights into potential contributors to prostate cancer disparities Open

Sophia M. Abusamra, Verónica Ochoa Cholán, Veda N. Giri, Susan T. Vadaparampil, Verónica Pérez‐Rosas , et al. · 2025

A Social Media Campaign and Web-Based Survey About Prostate Cancer Genetics: Mixed Methods Study (Preprint) Open

Amy Leader, Stacy Loeb, Preethi Selvan, Ashley Hunter, Rebecca Hartman , et al. · 2024

BACKGROUND Germline genetic variants are important for prostate cancer (PCa) management and hereditary cancer risk assessment, but testing is underused. Furthermore, patients are often unaware of the genetic connections to PCa. Social med…

Active Surveillance or Watchful Waiting for Intermediate-Risk Prostate Cancer, 2010-2020 Open

Ismail Ajjawi, Stacy Loeb, Matthew R. Cooperberg, William J. Catàlona, Cary P. Gross , et al. · 2024

This cross-sectional study evaluates trends and factors associated with selecting active surveillance or watchful waiting among individuals with intermediate-risk prostate cancer.

Can artificial intelligence evaluate the quality of <span>YouTube</span> videos on erectile dysfunction? Open

Roei Golan, Aden Swayze, Zachary M. Connelly, Justin Loloi, Kevin J. Campbell , et al. · 2024

Management of Patients with Advanced Prostate Cancer. Report from the 2024 Advanced Prostate Cancer Consensus Conference (APCCC) Open

Silke Gillessen, Fabio Turco, Ian D. Davis, Jason A. Efstathiou, Karim Fizazi , et al. · 2024

Adaptation of the socioecological model to address disparities in engagement of Black men in prostate cancer genetic testing Open

Amy Leader, Timothy R. Rebbeck, William Oh, Alpa V Patel, Eric P. Winer , et al. · 2024

Background Black men consistently have higher rates of prostate cancer (PCA)- related mortality. Advances in PCA treatment, screening, and hereditary cancer assessment center around germline testing (GT). Of concern is the significant unde…

Sleep and health improvement programme (SHIP) for patients with prostate cancer and caregivers Open

Stacy Loeb, Rebecca Robbins, Tatiana Sanchez‐Nolasco, Nataliya Byrne, Andrea Ruan , et al. · 2024

Objective The objective of this study is to determine whether a sleep and health improvement programme (SHIP) to promote healthy sleep, eating and physical activity would be feasible, acceptable and have a positive impact on lifestyle beha…

Readability and Information Quality in Cancer Information From a Free vs Paid Chatbot Open

David Musheyev, Alexander Pan, Preston W. Gross, Daniel Kamyab, Peter Kaplinsky , et al. · 2024

Importance The mainstream use of chatbots requires a thorough investigation of their readability and quality of information. Objective To identify readability and quality differences in information between a free and paywalled chatbot canc…

<i>BRCA1, BRCA2</i>, and Associated Cancer Risks and Management for Male Patients Open

Heather H. Cheng, Jeffrey Shevach, Elena Castro, Fergus J. Couch, Susan M. Domchek , et al. · 2024

Importance Half of all carriers of inherited cancer-predisposing variants in BRCA1 and BRCA2 are male, but the implications for their health are underrecognized compared to female individuals. Germline variants in BRCA1 and BRCA2 (also kno…

ChatGPT can help guide and empower patients after prostate cancer diagnosis Open

H. A. COLLIN, Kandice Keogh, Marnique Basto, Stacy Loeb, Matthew J. Roberts · 2024

Background/Objectives Patients often face uncertainty about what they should know after prostate cancer diagnosis. Web-based information is common but is at risk of being of poor quality or readability. Subjects/Methods We used ChatGPT, a …

Cancer misinformation on social media Open

Stacy Loeb, Aisha T. Langford, Marie A. Bragg, Robert Sherman, June M. Chan · 2024

Social media is widely used globally by patients, families of patients, health professionals, scientists, and other stakeholders who seek and share information related to cancer. Despite many benefits of social media for cancer care and re…

Plant-Based Diets and Disease Progression in Men With Prostate Cancer Open

Vivian N. Liu, Erin L. Van Blarigan, Li Zhang, Rebecca E. Graff, Stacy Loeb , et al. · 2024

Importance Plant-based diets are associated with many health and environmental benefits, including primary prevention of fatal prostate cancer, but less is known about postdiagnostic plant-based diet patterns in individuals with prostate c…

Engaging in Clinical Research and Practice Approaches that Reduce Environmental Impact Open

Stacy Loeb · 2024

‘It Just Makes Sense to Me’: A qualitative study exploring patient decision‐making and experiences with prostate MRI during active surveillance for prostate cancer Open

Ryan Sutherland, Cary P. Gross, Xiaomei Ma, Farah Jeong, Tyler M. Seibert , et al. · 2024

Introduction Although prostate magnetic resonance imaging (MRI) is commonly used in the diagnosis, staging and active surveillance of prostate cancer, little is known about patient perspectives on MRI. Methods We performed a qualitative st…

The Lancet Commission on prostate cancer: planning for the surge in cases Open

Nicholas D. James, Ian F. Tannock, James N’Dow, Felix Y. Feng, Silke Gillessen , et al. · 2024

PRECISE Version 2: Updated Recommendations for Reporting Prostate Magnetic Resonance Imaging in Patients on Active Surveillance for Prostate Cancer Open

Cameron Englman, Davide Maffei, Clare Allen, Alex Kirkham, Peter C. Albertsen , et al. · 2024

TARGET: A Randomized, Noninferiority Trial of a Pretest, Patient-Driven Genetic Education Webtool Versus Genetic Counseling for Prostate Cancer Germline Testing Open

Stacy Loeb, Scott W. Keith, Heather H. Cheng, Amy Leader, Laura Gross , et al. · 2024

PURPOSE Germline genetic testing (GT) is important for prostate cancer (PCA) management, clinical trial eligibility, and hereditary cancer risk. However, GT is underutilized and there is a shortage of genetic counselors. To address these g…

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